| PROTAFFIN BIOTECHNOLOGIE AG Patent applications |
| Patent application number | Title | Published |
|---|
| 20120046218 | GLYCOSAMINOGLYCAN-ANTAGONISING MCP-I MUTANTS AND METHODS OF USING SAME - Novel mutants of human monocyte chemoattractant protein 1 (MCP-1) with increased glycosaminoglycan (GAG) binding affinity and knocked-out or reduced GPCR activity compared to wild type MCP-1, and their use for therapeutic treatment of inflammatory diseases. | 02-23-2012 |
| 20110229433 | USE OF MODIFIED INTERLEUKIN-8 PROTEINS FOR TREATING REPERFUSION INJURY OR TRANSPLANT REJECTION - The present invention relates to the use of a modified interleukin 8 (IL-8) having increased GAG binding affinity and further inhibited or down-regulated biological activity compared to the respective wild type IL-8 for preparing a medicament for the prevention and/or treatment of ischemia reperfusion injury and/or transplant rejection in patients. | 09-22-2011 |
| 20110144305 | GAG BINDING PROTEIN - A method is provided for introducing a GAG binding site into a protein comprising the steps:
| 06-16-2011 |
| 20100331237 | GAG BINDING PROTEINS - A method is provided for introducing a GAG binding site into a protein comprising the steps:
| 12-30-2010 |
| 20100298203 | SDF-I-BASED GLYCOSAMINOGLYCAN ANTAGONISTS AND METHODS OF USING SAME - The present invention relates to novel mutants of human stromal cell-derived factor-1 which exhibit increased glycosaminoglycan (GAG) binding affinity and inhibited or down-regulated GPCR activity compared to wild type SDF-1, methods for producing these mutants and to their use for preparing medicaments for the treatment of cancer. | 11-25-2010 |
| 20100197583 | Glycosaminoglycan-antagonising MCP-1 Mutants and Methods of Using Same - Novel mutants of human monocyte chemoattractant protein 1 (MCP-1) with increased glycosaminoglycan (GAG) binding affinity and knocked-out or reduced GPCR activity compared to wild type MCP-1, and their use for therapeutic treatment of inflammatory diseases. | 08-05-2010 |
| 20100035294 | SYSTEM TO ASSESS THE BIOLOGICAL ACTIVITY OF CHEMOATTRACTANTS - The present invention relates to a system for measuring the biological activity of chemoattractants comprising at least two units separated by a semipermeable carrier wherein biologically active carbohydrate structures, preferably glycosaminoglycan (GAG) structures, are immobilized on the surface of said carrier. According to the invention, this system can be used for fast and economic measurement of the degree of cell mobility and chemotactic activity. | 02-11-2010 |
| 20090005541 | GAG BINDING PROTEIN - A method is provided for introducing a GAG binding site into a protein comprising the steps:
| 01-01-2009 |
