Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Promedior, Inc.
| Promedior, Inc. Patent applications | ||
| Patent application number | Title | Published |
|---|---|---|
| 20100323970 | SAP VARIANTS AND THEIR USE - Polypeptides are susceptible to denaturation or enzymatic degradation in the blood, liver or kidney. Due to the low stability of some polypeptides, it has been required to administer polypeptide drugs in a sustained frequency to a subject in order to maintain an effective plasma concentration of the active substance. Furthermore, pharmaceutical compositions of therapeutic peptides preferably have a shelf-life of several years in order to be suitable for common use. However, peptide compositions are inherently unstable due to sensitivity towards chemical and physical degradation. In part, the invention provides SAP variant proteins, compositions, pharmaceutical preparations and formulations having a prolonged in vivo half-life, prolonged shelf-life, or rather increased in vitro stability, or increased manufacturing efficiency compared to human SAP. Advantages of increased plasma half-life include, but are not limited to, reducing the amount and/or frequency of dosing. | 12-23-2010 |
| 20100111898 | CONJOINT THERAPY FOR TREATING FIBROTIC DISEASES - The present invention relates to improved methods of treating fibrotic or fibroproliferative disorders. Conjoint therapies are provided comprising the combination of one or more fibrocyte suppressors and one or more profibrotic factor antagonists or anti-fibrotic agents. | 05-06-2010 |
| 20090202520 | Treatment and diagnostic methods for fibrosis related disorders - Compositions and methods are provided for the treatment of fibrosis related disorders utilizing the ratio of the concentration of serum amyloid P(SAP) to C-reactive protein (CRP) in a patient. The methods may further comprise determining the R131/H131 polymorphism of FcγRIIA. Diagnostic methods are also provided. | 08-13-2009 |
| 20090074754 | Methods and compositions useful in the treatment of mucositis - In certain aspects, the present invention provides compositions and methods for treating mucositis. | 03-19-2009 |