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President and Fellow of Harvard College

President and Fellow of Harvard College Patent applications
Patent application numberTitlePublished
20100242124COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF ULCERATIVE COLITIS AND COLON CANCER AND SCREENING METHODS TO IDENTIFY SAME - The instant invention is based, at least in part, on the discovery that T-bet maintains host commensal relationships in the gastrointestinal tract. Accordingly, this invention provides methods of treating and/or preventing ulcerative colitis, and/or colon cancer, and/or preventing colonization of a subject's gastrointestinal tract with commensal bacteria that promote ulcerative colitis as well as methods of identifying agents that treat and prevent the same.09-23-2010
20080234498Pyrovalerone Analogues and Therapeutic Uses Thereof - New compounds that bind to monoamine transporters are described. The compounds of the present invention can be racemic or pure R— or S-enantiomers. Certain preferred compounds of the present invention have a high selectively dopamine transporter versus the serotonin transporter. Preferred monoamine transporters for the practice of the present invention include the dopamine transporter, the serotonin transporter and the norepinephrine transporter.09-25-2008