| 20090304667 | Method of Regulating Mammalian Target-of-Rapamycin Activity by Interaction Between Phospholipase D and RHEB - The present invention relates to method of regulating mammalian target-of-rapamycin (mTOR) based on a novel finding of a regulating mechanism of mTOR by a phospholipase D (PLD), and Ras homolog enriched in brain (Rheb). Further, the present invention also relates to a method of screening inhibitors of mTOR, and a method and a composition for treating mTOR-related metabolic diseases by inhibitin mTOR. | 12-10-2009 |
