| Piramal Life Sciences Limited Patent applications |
| Patent application number | Title | Published |
|---|
| 20110312970 | PYRIDINE DERIVATIVES FOR THE TREATMENT OF METABOLIC DISORDERS RELATED TO INSULIN RESISTANCE OR HYPERGLYCEMIA - The present invention provides novel compounds represented by the general formula (I): | 12-22-2011 |
| 20110274695 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS - The invention provides the compounds of formula (I) or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutical compositions comprising one or more compounds of formula I or intermediates thereof and one more of pharmaceutically acceptable carriers, vehicles or diluents. The invention further provides methods of preparation and methods of use of prodrugs including NO-releasing prodrugs, double prodrugs and mutual prodrugs comprising the compounds of formula I. | 11-10-2011 |
| 20110269709 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS - The invention provides the compounds of formula (I) or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutical compositions comprising one or more compounds of formula I or intermediates thereof and one more of pharmaceutically acceptable carriers, vehicles or diluents. The invention further provides methods of preparation and methods of use of prodrugs including NO-releasing prodrugs, double prodrugs and mutual prodrugs comprising the compounds of formula I. | 11-03-2011 |
| 20110263526 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents - The present invention relates to nitric oxide releasing prodrugs of known drugs or therapeutic agents which are represented herein as compounds of formula (I) wherein the drugs or therapeutic agents contain one or more functional groups independently selected from a carboxylic acid, an amino, a hydroxyl and a sulfhydryl group. The invention also relates to processes for the preparation of the nitric oxide releasing prodrugs (the compounds of formula (I)), to pharmaceutical compositions containing them and to methods of using the prodrugs. | 10-27-2011 |
| 20110177180 | HERBAL COMPOSITION AND METHOD FOR THE TREATMENT OF VIRAL INFECTION - The present invention relates to a herbal composition comprising extract of the plant | 07-21-2011 |
| 20110151469 | INTERFERON EPSILON (IFNE1) AS A MARKER FOR TARGETED CANCER THERAPY - The present invention relates to a method employing Interferon Epsilon (IFNE1) as a therapeutic response, prognostic, or pharmacodynamic marker for cancer chemotherapeutic treatment involving the use of cyclin dependent kinase (CDK) inhibitors. The inventors have identified IFNE1 as a biomarker transcript that is upregulated when cancer cells are treated with CDK inhibitors. In an embodiment, the method of the invention includes measuring a level of IFNE1 mRNA or IFNE1 protein in a subject's tumor, blood or other tissue. An increase in the level of IFNE1 compared to control level can indicate that the CDK inhibitor has produced a therapeutic response or can determine whether a tumor is sensitive to a CDK inhibitor. | 06-23-2011 |
| 20110111067 | ORAL HERBAL COMPOSITION FOR THE TREATMENT OF ORAL CANDIDIASIS - An oral herbal composition comprising a therapeutically effective amount of an extract derived from the berries of a plant, | 05-12-2011 |
| 20100324026 | FUSED TRICYCLIC COMPOUNDS AS INHIBITORS OF TUMOR NECROSIS FACTOR-ALPHA - Compounds of formula 1: | 12-23-2010 |
| 20100305094 | FUSED TRICYCLIC COMPOUNDS AS INHIBITORS OF TUMOR NECROSIS FACTOR-ALPHA - Compounds of formula 1: | 12-02-2010 |
| 20100305057 | SYNERGISTIC PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF CANCER - A novel pharmaceutical combination comprising a cytotoxic antineoplastic agent selected from a the group consisting of paclitaxel, docetaxel, doxorubicin and gemcitabine or a pharmaceutically acceptable salt thereof and at least one cyclin dependent kinase (CDK) inhibitor; wherein the said combination exhibits synergistic effects when used in the treatment of cancer. The invention also relates to a method for the treatment of cancer, using a therapeutically effective amount of the said combination. | 12-02-2010 |
| 20100267690 | TRICYCLIC GUANIDINE DERIVATIVES AS SODIUM-PROTON EXCHANGE INHIBITORS - Guanidine derivatives having a condensed tricyclic ring of formula 1: | 10-21-2010 |
| 20100168008 | METHOD OF USE OF EPIREGULIN PROTEIN AND NUCLEIC ACID ENCODING THE SAME IN INFLAMMATORY CONDITIONS - The present invention relates to nucleotide and protein sequences of epiregulin and epiregulin like proteins and nucleotides and methods employing them as a drug response marker in inflammatory conditions. The invention also provides epiregulin protein for treatment of inflammatory conditions like psoriasis and rheumatoid arthritis alone or in combination with one or more anti-inflammatory compounds. | 07-01-2010 |
| 20100034746 | ANIMAL MODEL, SYSTEM, AND METHOD FOR SCREENING COMPOUNDS FOR ANTITHROMBOTIC AND/OR THROMBOLYTIC ACTIVITY - The present invention relates to a method for evaluating a test compound for antithrombotic activity, thrombolytic activity, or a combination thereof. This method can include providing or employing a donor test animal and a recipient test animal. The donor and recipient test animals can have been pretreated with test compound. The donor test animal can be configured to provide oxygenated blood to the recipient test animal through a thrombus inducing system. This method also includes initiating transport of blood from the donor test animal to the recipient test animal through the thrombus inducing system. The method can include interrupting respiration of the recipient test animal and determining the length of time that the recipient test animal survives. In this method, a survival time longer than a predetermined threshold time indicates that the test compound has antithrombotic activity, thrombolytic activity, or a combination thereof. | 02-11-2010 |
| 20100028472 | HERBAL COMPOSITION AND PROCESS FOR ITS PREPARATION - A herbal composition comprising a therapeutically effective amount of the extract of | 02-04-2010 |
| 20100010002 | ANTICANCER USE OF CAFFEIC ACID AND ITS DERIVATIVES - The present invention relates to the use of caffeic acid or a derivative thereof represented by the following general formula (1) | 01-14-2010 |
| 20090297644 | HERBAL COMPOSITIONS FOR THE TREATMENT OF DISEASES OF THE ORAL CAVITY - The present invention relates to bioadhesive compositions for oral application, which comprise a curcuminoid substance as an active ingredient. The present invention also relates to method of using said bioadhesive composition for the prevention and treatment of periodontal diseases such as gingivitis and other periodontal diseases. | 12-03-2009 |
| 20090291155 | Herbal Composition - The present invention relates to a novel herbal composition comprising extract of leaves of | 11-26-2009 |
| 20090269427 | HERBAL COMPOSITION FOR INFLAMMATORY DISORDERS - This invention relates to a novel herbal composition comprising an extract of flowering and fruiting heads of the plant, | 10-29-2009 |
| 20090104297 | HERBAL COMPOSITION FOR TREATMENT OF INFECTIONS CAUSED BY DERMATOPHYTES - The present invention relates to a novel herbal composition comprising extract of roots of the plant | 04-23-2009 |
| 20090076094 | NOVEL ANTIBACTERIAL COMPOUNDS - This invention relates to a novel purified compound PM181104, of formula: | 03-19-2009 |
| 20080254157 | Herbal composition for inflammatory disorders - This invention relates to a novel herbal composition comprising an extract of flowering and fruiting heads of the plant, | 10-16-2008 |
