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Philadelphia Health & Education Corporation D/B/A

Philadelphia Health & Education Corporation D/B/A Patent applications
Patent application numberTitlePublished
20100104580Altered Immunogenic Landscape in HIV-1 Envelope Proteins - The present invention provides compositions and methods useful in the prevention and treatment of HIV-1 infection in a host subject. High affinity binding of an allosteric dual antagonist to HIV-1 gp120 induces a conformational change in the gp 120 protein that traps the gp 120 protein in a three-dimensional structure that suppresses its function and exposes novel antigenic epitopes to host immune surveillance.04-29-2010