| Philadelphia Health & Education Corporation d/b/a Drexel University College of Medicine Patent applications |
| Patent application number | Title | Published |
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| 20110277618 | METHOD AND APPARATUS FOR BRAIDING MICRO STRANDS - A method and apparatus for fabricating microbraided structures is provided. A microbraiding device includes first and second carrier members that are movable with respect to each other. Each carrier includes a plurality of shelters. Spool-less strands of microfiber are retained in shuttles that are movable between the first and second shelters under magnetic forces. The microbraid structure is fabricated as the shuttles move between the first shelters, and as the first carrier member moves relative to the second carrier member. | 11-17-2011 |
| 20110264117 | TISSUE JOINING DEVICE AND INSTRUMENT FOR ENABLING USE OF A TISSUE JOINING DEVICE - A tissue joining device and a surgical instrument for employing the tissue joining device are provided. The tissue joining device may be designed such that a first member may be inserted into a second member in discrete increments so that two lumen structures can properly be combined. | 10-27-2011 |
| 20110256538 | EPIGENOMIC DNA MODIFICATIONS FOR TISSUE TYPING, EARLY CANCER DETECTION, AND DISEASE MANAGEMENT - Provided herein is a suitable method for detecting the presence or absence of a cancer in an individual, by determining the level of methylation of the sense strand of a selected regulatory region of a tumor suppressor gene. Also provided herein is a method of detecting the presence or absence a cancer in an individual by determining if there is an apparent 100% methylation by assay of the CpG sites in the anti-sense strand of a selected regulatory region of a tumor suppressor gene. Also provided herein is a method of tissue typing by determining the level of methylation of the anti-sense strand of a selected regulatory region of a tumor suppressor gene indicating an enhanced likelihood that a tissue is liver. | 10-20-2011 |
| 20110226610 | SYNTHESIS OF NITRODIBENZYLFURAN CHROMOPHORE FOR PHOTODEPROTECTION OF ORGANIC MOLECULES - Inventors have developed a chromophore (nitrodibenzylfuranyl, or NBDF) for ultra efficient uncaging of a caged substrate (e.g., an organic molecule such as, for example, an amino acid, a biological molecules, such as, for example, second messengers inside cells). Photolysis of a NBDF derivative of EGTA (i.e. caged calcium) is about 50 times more efficient than others calcium cages (the quantum yield of photolysis is 0.6 and the extinction coefficient is 18,400. NDBF-EGTA has a 2-photon cross section of about 0.3-0.6 GM). | 09-22-2011 |
| 20110171203 | METHODS FOR TREATING NEOPLASTIC DISEASE TARGETING O-LINKED N-ACETYLGLUCOSAMINE MODIFICATIONS OF CELLULAR PROTEIN - Methods for treating a neoplastic disease in a mammalian subject are provided. The method provides administering an inhibitor of O-GlcNAc transferase in an amount effective to reduce or eliminate the neoplastic disease in the mammalian subject. Method for diagnosing a risk factor for a neoplastic disease in a mammalian subject and methods for identifying a test compound which inhibits a hexosamine signaling pathway in a cell or tissue are provided. | 07-14-2011 |
| 20100317127 | DIAGNOSIS OF LIVER PATHOLOGY THROUGH ASSESMENT OF PROTEIN GLYCOSYLATION - Methods for diagnosing pathology of the liver in a subject suspected of having such pathology are disclosed. The methods comprise quantifiably detecting lectin binding on proteins in biological fluids, and comparing the detected lectin binding with reference values for the binding of lectin of such proteins in healthy or disease states. | 12-16-2010 |
| 20100216721 | Inhibition of HIV-1 Infection by Potent Metallocene Conjugated Peptide Through Conformational Entrapment of Envelope GP120 - The invention provides a peptide triazole conjugate and derivatives thereof, and methods of its use. | 08-26-2010 |
| 20100094149 | Noninvasive Ultrasound Cardiac Pacemaker and Defibrillator - A device for providing extracorporeal cardiac pacing. The device includes an ultrasound transducer mountable to the external thorax of a patient and an ultrasound generator for transmitting ultrasound pulses to the ultrasound transducer. The heart rate of a patient is monitored by the device. A controller evaluates the heartbeat as compared with threshold criteria for stimulation of the heart and causes the ultrasound generator to deliver ultrasound pulses to the ultrasound transducer at a prescribed intensity, frequency, and pulse duration. | 04-15-2010 |
| 20090099441 | BRAIDED ELECTRODES - Electrodes for intracorporeal and other uses are provided. The invention features sterilizable, braided electrodes which are formed of or include conductive elements in electronic communication with a plurality of sites for electrical stimulation or sensing. Other active elements may be included in the braided electrodes. | 04-16-2009 |
| 20080319247 | Method of local therapy using magnetizable thermoplastic implant - A method for local therapies using heat generating implants comprising magnetic or magnetizable features or objects distributed in a solidified moldable matrix to treat bone infection or loosening of implants by the mechanism of hyperthermia or thermoablation. | 12-25-2008 |
| 20080318247 | Biomarker for cardiac transplant rejection - The invention provides a method of diagnosing a disease or disorder featuring an abnormal level of a ring-containing molecule in a tissue. In one embodiment, a method of diagnosing organ transplant rejection is provided. | 12-25-2008 |
| 20080220181 | Method of loading a nanotube structure and loaded nanotube structure - Nanotubes loaded with materials, such as active species, and methods to load materials into nanotubes are disclosed. The method includes flowing a medium containing the material to be loaded through the interior volume of the nanotube, wherein it is retained, optionally by a crosslinking or polymerization reaction. Flowing the medium occurs under different conditions and processes, including centrifuging and size exclusion methods. | 09-11-2008 |
