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PHARMACIA & UPJOHN CO.

PHARMACIA & UPJOHN CO. Patent applications
Patent application numberTitlePublished
20090075316Alzheimer's Disease Secretase, APP Substrates Therefor and Uses Therefor - The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. The invention further provides a modified APP protein and associated nucleic acids, peptides, vectors, cells, and cell isolates, and assays that are particularly useful for identifying candidate therapeutics for treatment or prevention of Alzheimer's disease.03-19-2009