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PHARMAAWARE SEPSIS B.V.

PHARMAAWARE SEPSIS B.V. Patent applications
Patent application numberTitlePublished
20110142817MEANS AND METHOD FOR TREATING AND/OR PREVENTING NECROTIZING ENTEROCOLITIS - Compositions comprising a source of alkaline phosphatase that prevent or reduce toxic influx of lipopolysaccharide (LPS) through mucosal layers of a mamalian body cavity and methods of using these compositions for those purposes are disclosed. Such a source of alkaline phosphatase, preferably in a medical food such as infant milk formula, is eaten, drunk or otherwise administered for prophylaxis or treatment of LPS-mediated or LPS-exacerbated disease.06-16-2011
20090010912Use of Alkaline Phosphatase for the Detoxification of Lps Present at Mucosal Barriers - The present invention provides a use for alkaline phosphatase for the manufacture of a medicament for the prevention or reduction of toxic LPS influx through a mucosal lining of a mammalian body cavity. A source of alkaline phosphatase is administered for the prophylaxis or treatment of LPS mediated or exacerbated diseases. The invention also provides compositions comprising a source of alkaline phosphatase for the prevention or reduction of (toxic) LPS influx or passage through mucosal layers.01-08-2009