Inventors list

Assignees list

Classification tree browser

Top 100 Inventors

Top 100 Assignees


PHARMA MAR, S.A.

PHARMA MAR, S.A. Patent applications
Patent application numberTitlePublished
20120107417Effective Antitumor Treatments - ET-743 is used in the preparation of a medicament for an effective treatment of a tumour by combination therapy employing ET-743 with another drug.05-03-2012
20120041063ANTITUMORAL COMPOUNDS - A compound of general formula (I) 02-16-2012
20110237520Anticancer Compounds - Compounds of general formula I:09-29-2011
20110207674ANTITUMORAL COMPOUNDS - Antitumoral compounds of Formula I, and pharmaceutically acceptable salts, derivatives, tautomers, prodrugs or stereoisomers thereof 08-25-2011
20110105409Anticancer Compounds - Anticancer compounds of general formula I:05-05-2011
20110076343Multiple Myeloma Treatments - Methods for treating cancer by using compound PM00104, in particular, for treating multiple myeloma are provided.03-31-2011
20110070232Combination Therapy with an Antitumor Alkaloid - The present invention relates to combinations of PM00104 with other anticancer drugs, and the use of these combinations in the treatment of cancer.03-24-2011
20110034549Antitumoral Compounds - A compound of general formula (I)02-10-2011
20110015135Antitumoral Treatments - The present invention relates to combinations of PM02734 with another anticancer drug selected from Cisplatin, Gemcitabine, Paclitaxel, Oxaliplatin, 5-Fluorouracil, Trabectedin, Rapamycin, and Sunitinib, and the use of these combinations in the treatment of cancer.01-20-2011
20100323021ANTITUMORAL TREATMENTS - The present invention relates to colloidal metal nanoparticles conjugated with Kahalalide F, or an analogue thereof, and their use in the treatment of cancer. The invention also relates to a method for increasing the antitumoral activity of Kahalalide F, or an analogue thereof, which comprises conjugating the Kahalalide F, on an analogue thereof, with a colloidal metal nanoparticle.12-23-2010
20100292163Antitumoral Compounds - Antitumoral compounds of Formula I, and pharmaceutically acceptable salts, derivatives, tautomers, prodrugs or stereoisomers thereof11-18-2010
20100280108Antitumoral Compounds - A compound of general formula (I)11-04-2010
20100267732Prognostic Molecular Markers for ET-743 Treatment - The present invention relates to the use of ecteinascidin 743 in human patients having certain molecular markers profile which has been associated with the outcome of ET-743 chemotherapy. In particular, the invention relates to the use of ecteinascidin 743 in patients having high expression levels of XPG mRNA or protein and/or having a “wild type” genotype for Asp1104His SNP of XPG gene.10-21-2010
20100240595Improved Antitumoral Treatments - The present invention relates to combinations of Aplidine with Gemcitabine, and the use of these combinations in the treatment of cancer.09-23-2010
20100226919Antitumoral Treatments - The present invention relates to combinations of PM02734 with EGFR tyrosine kinase inhibitors, and the use of these combinations in the treatment of cancer.09-09-2010
20100216817Antitumoral Tetrahydro-Pyrimidines - Antitumoral compounds of the formula (I) wherein X is O, S, or NRa, obtained from a maze coral of the family Meandrinidae, genus 08-26-2010
20100048690ANTITUMORAL DIHYDROPYRAN-2-ONE COMPOUNDS - Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus 02-25-2010
20100048596Indole Derivatives as Antitumoral Compounds - Antitumoural compounds of general formula (I); wherein Ar is an heterocyclic group of formula (a) and R02-25-2010
20100041594Use of Aplidine for the Treatment of Pancreatic Cancer - Aplidine is active against cancer of the pancreas, including metastatic pancreatic cancer.02-18-2010
20100009906Anticancer Treatments - A method of treating the human body for cancer comprises administering an effective therapeutic amount of docetaxel in combination with an effective therapeutic amount of ET-743.01-14-2010
20090324744Effective Antitumor Treatments - ET-743 is used in the preparation of a medicament for an effective treatment of a tumour by combination therapy employing ET-743 with another drug.12-31-2009
20090298752APLIDINE TREATMENT OF CANCERS - Aplidine demonstrates considerable promise in phase (I) clinical trials for treatment of tumors, and various dosing regimes are given. Tumor reduction has been observed in several tumor types including renal carcinoma, colorectal cancer, lung carcinoid, medullary thyroid carcinomas and melanoma. It has also been found that aplidine has a role in inhibiting angiogenesis, complementing the anti-tumor activity.12-03-2009
20090246168ANTITUMORAL TREATMENTS - The present invention relates to combinations of aplidine or aplidine analogues with other antitumoral agents, and the use of these combinations in the treatment of cancer, in particular in the treatment of lung cancer, breast cancer, colon cancer, prostate cancer, renal cancer, melanoma, multiple myeloma, leukemia and lymphoma.10-01-2009
20090197901VARIOLIN DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS - Variolin derivatives of formula (5) are provided, wherein the substituent groups defined by X08-06-2009
20090186938ANTITUMORAL DIHYDROPYRAN-2-ONE COMPOUNDS - Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus 07-23-2009
20090163507SYNTHESIS OF NATURALLY OCCURING ECTEINASCIDINS AND RELATED COMPOUNDS - Ecteinascidin compounds with a quinone ring for ring E are active as anti-cancer agents. Related processes and compounds are provided.06-25-2009
20090130675Genes Involved in the Biosynthesis of Thiocoraline and Heterologous Production of Same - The invention relates to genes involved in the biosynthesis of thiocoraline and to the heterologous production of same. According to the invention, the cluster of genes responsible for the biosynthesis of thiocoraline was identified and cloned. Said cluster of genes can be used in the heterologous production of thiocoraline which has an antitumor and antibacterial activity.05-21-2009
20090124647Indole Derivatives as Antitumoral Compounds - Antitumoural compounds of general formula (I); wherein Ar is an heterocyclic group of formula (a) and R05-14-2009
20090076016FORMULATIONS COMPRISING JORUMYCIN-, RENIERAMYCIN-, SAFRACIN- OR SAFRAMYCIN-RELATED COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES - Jorumycin, renieramycin, safracin and saframycin related compounds formulations, methods of preparing the same, articles of manufacture and kits with such formulations, and methods of treating proliferative diseases with the same formulations are provided.03-19-2009
20090030068Antitumour Compounds - The invention relates to novel antitumor compounds of general formula01-29-2009
20080318849Kahalalide F and Related Compounds - A process is provided for preparing kahalalide F and which leads to other kahalalide mimic compounds having useful biological activity.12-25-2008
20080234363Antitumoral Compounds - Compounds of general formula (I), wherein R09-25-2008

Patent applications by PHARMA MAR, S.A.