| PARI PHARMA GMBH Patent applications |
| Patent application number | Title | Published |
|---|
| 20120118991 | CONCENTRATED MAST CELL STABILIZING PHARMACEUTICAL FORMULATIONS - Liquid aqueous pharmaceutical solutions, containing a mast cell stabilizing active agent for application to the upper and lower respiratory tract or in the eye are provided. The solutions comprise both a non-ionic and an ionic tonicity-adjusting excipient. They are particularly useful for the aerosol treatment of respiratory diseases such as asthma. Furthermore, methods for nebulization of these solutions and methods of packaging the solutions are provided. | 05-17-2012 |
| 20120085344 | METHOD FOR OPERATING AN AEROSOL INHALATION DEVICE AND AEROSOL INHALATION DEVICE - In a first aspect, the invention relates to a method for operating an aerosol inhalation device ( | 04-12-2012 |
| 20120060833 | INHALATION THERAPY DEVICE - The invention relates to an inhalation therapy device having an aerosol generator ( | 03-15-2012 |
| 20120037154 | AEROSOL THERAPY DEVICE - The invention relates to an aerosol therapy device comprising: a housing; an aerosol generator, which is arranged in the housing; an air inlet ( | 02-16-2012 |
| 20110155768 | FLUID DROPLET PRODUCTION APPARATUS AND METHOD - A fluid dispersion device comprises a substrate having an outer section and an inner section, said inner section of the substrate having an aperture, a dispersion element positioned at said aperture of said substrate, and an actuator arranged to coaxially surround said aperture of said substrate, wherein the outer edge of said inner section of said substrate is coupled to said outer section of said substrate by a plurality of resilient members. | 06-30-2011 |
| 20110146670 | NEBULISER FOR VENTILATION MACHINES AND A VENTILATION MACHINE COMPRISING SUCH A NEBULISER - Atomizer for a ventilation machine with a ventilator ( | 06-23-2011 |
| 20110139150 | AEROSOL GENERATING MEANS FOR INHALATION THERAPY DEVICES - The invention describes an aerosol generator for inhalation therapy devices, in which an oscillatable assembly, consisting of at least a membrane and an oscillation generator, is mounted in an encapsulating means such that at least the membrane is exposed for the supply of liquid and the generation of an aerosol, whereas the remaining parts of the oscillatable assembly are protected. Mounting occurs by means of a flexible passage such that the oscillatory motions of the oscillatable assembly are not negatively affected. | 06-16-2011 |
| 20100316576 | AEROSOLS FOR SINUNASAL DRUG DELIVERY - A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterised in that it exhibits a low effective flow rate of less than about 5 litres per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis. | 12-16-2010 |
| 20090304604 | PULMONARY DELIVERY OF ALPHA-1 PROTEINASE INHIBITOR - The present invention relates to a system that includes a pharmaceutical composition of a purified, stable, active alpha-1 proteinase inhibitor (API) in a form of a ready to use sterile solution and an inhalation nebulizer, and to methods of use thereof for treating pulmonary diseases. | 12-10-2009 |
| 20090293868 | Inhalation Therapy Device Comprising an Ampoule for Storing a Medicament To Be Nebulized - An inhalation therapy device includes an atomizer for atomizing a drug which is advantageously present in the form of a fluid into an atomization chamber so that an aerosol or mist is provided in the atomization chamber. The patient or user can inhale the aerosol produced by the atomizer from the atomization chamber via a mouthpiece. The ampoule is inserted into an ampoule holder holding the fluid-containing ampoule. The inhalation therapy device also includes an opening unit for opening the fluid-containing ampoule. The ampoule holder advantageously includes a first part, disposed displaceably in relation to the opening unit, thereby allowing an ampoule present in the ampoule holder to be displaced in the direction of the opening unit. | 12-03-2009 |
| 20090232744 | Macrolide compositions having improved taste and stability - The invention provides an aqueous pharmaceutical composition for administration as an aerosol to the respiratory tract, nose or oropharyngeal region comprising (i) a macrolide having a poor taste and poor chemical stability in aqueous solution; (ii) at least one salt selected from the group consisting of sodium gluconate, sodium aspartate, sodium acetate, sodium lactate, sodium succinate, sodium maleate, magnesium gluconate, magnesium aspartate, magnesium citrate, magnesium acetate, magnesium lactate, magnesium succinate, and magnesium maleate; or mixtures thereof and (iii) a taste-masking agent different from said salt; wherein (a) the concentration of said macrolide in the composition is in the range of about 0.25 wt.-% to about 15 wt.-%; (b) the molar ratio of said macrolide:said salt is in the range from about 1:0.5 to about 1:100; (c) the pH of the composition is in the range of about 3 to 9; and (d) the osmolality of the composition is in the range of about 150 mOsmol/kg to about 1500 mOsmol/kg. The invention further provides a method of generating an aerosol, preferably by means of a nebuliser, which uses such an aqueous pharmaceutical composition. The macrolide may be used alone or in combination with other drugs. The composition is suitable to treat inflammatory disorders and/or infections of the respiratory tract. It has an improved taste and stability. | 09-17-2009 |
| 20090169607 | Pharmaceutical Compositions Comprising Cyclosporin - The invention relates to liquid pharmaceutical compositions containing: a) a therapeutically effective dose of a cyclosporin; b) an aqueous carrier liquid; c) a first solubilizing substance selected among the group of phospholipids; and d) a second solubilizing substance selected among the group of non-ionic surfactants. Preferably, the cyclosporin is liposome solubilized. The inventive composition is suitable for oral, parenteral, nasal, mucosal, topical, and particularly pulmonary application in the form of an aerosol. | 07-02-2009 |
| 20090137950 | DISPOSABLE AMPOULE FOR AN AEROSOL GENERATING DEVICE - Disposable ampoule for use in an aerosol generating device, comprising: a medicament container that contains a medicament and is formed of a container body ( | 05-28-2009 |
| 20090120431 | Inhalation Treatment Device and Method for the Operation Thereof - The invention relates to an inhalation nebulizer ( | 05-14-2009 |
| 20090025713 | Nebulised Antibiotics for Inhalation Therapy - The present invention provides pharmaceutical aerosols which are useful for the prevention or treatment of infectious diseases of the airways, such as the lungs, the bronchi, or the sinunasal cavities. The aerosols comprise an active agent selected from the group of quinolone antibiotics. Also disclosed are liquid and solid compositions suitable for being converted into the aerosols, and kits comprising such compositions. | 01-29-2009 |
| 20080308096 | Aerosol Generating Device and Inhalation Therapy Unit Provided with This Device - An aerosol generating device includes a membrane for atomizing a liquid; an actuating device, which is coupled to the membrane so that this membrane is set in oscillatory motion when activated by electric signals; and a flexible substrate, which has electric lines for supplying electric signals to the actuating device and is designed for fastening the aerosol generating device to a fastening area of an inhalation therapy unit, and on which the membrane and the actuating device are held. | 12-18-2008 |
| 20080299049 | Inhalation nebulizer - The aerosol generator of an inhalation therapy device according to a preferred embodiment of the invention continuously produces an aerosol at a generation rate of about 0.2 ml/min to about 1.5 ml/min, preferably 0.4 ml/min to about 1.2 ml/min and the mixing chamber has a volume of about 60 ml to about 150 ml, preferably about 80 ml to about 120 ml, and even more preferably about 90 to about 110 ml. While the patient inhales through the inhalation therapy device, the generated aerosol is inhaled by the patient. While the patient exhales into the inhalation therapy device, the generated aerosol is collected in the mixing chamber. Due to the specific size of the mixing chamber, the continuously generated aerosol can accumulate therein without losses even when the exhalation phase is longer than the inhalation phase like in the case of emphysema. | 12-04-2008 |
