PAION Deutschland GmbH Patent applications |
Patent application number | Title | Published |
20140256640 | TREATMENT OF COAGULOPATHY WITH HYPERFIBRINOLYSIS - The present invention relates to the use of thrombomodulin analogues for the manufacture of a medicament for the treatment of coagulopathy with hyperfibrinolysis, such as haemophilia disorders. These thrombomodulin analogs exhibit at therapeutically effective dosages an antifibrinolytic effect. Novel protein modifications together with methods for their identification are disclosed. | 09-11-2014 |
20130058939 | TREATMENT OF NEUROLOGICAL OR NEURODEGENERATIVE DISORDERS - The invention relates to a protein or peptide consisting of a kringle protein or peptide and its use for the treatment of neurological or neurodegenerative disorders, in particular stroke. The invention relates also to an isolated antibody of fragment thereof which binds to the N-terminal domain of the NMDA receptor subunit NR1 (anti-NR1 antibody), whereas binding of the antibody or the fragment thereof prevents the cleavage of the extracellular domain of the NR1 subunit, or the fragment and its use for the treatment of neurological or neurodegenerative disorders, in particular stroke. The invention relates further to a pharmaceutical composition containing said kringle protein or peptide or anti-NR1 antibody. | 03-07-2013 |
20120270789 | TREATMENT OF COAGULOPATHY WITH HYPERFIBRINOLYSIS - The present invention relates to the use of thrombomodulin analogues for the manufacture of a medicament for the treatment of coagulopathy with hyperfibrinolysis, such as haemophilia disorders. These thrombomodulin analogs exhibit at therapeutically effective dosages an antifibrinolytic effect. Novel protein modifications together with methods for their identification are disclosed. | 10-25-2012 |
20110144024 | PREVENTION AND TREATMENT OF RADIATION INJURY - The invention relates to the field of radiation injury. More particularly, this invention relates to the protection against/prevention of and treatment of diseases caused by ionizing radiation by the use of thrombomodulin. | 06-16-2011 |