ORTHOX LIMITED Patent applications |
Patent application number | Title | Published |
20140277452 | IMPLANTABLE REPAIR DEVICE - An implantable repair device for the repair, augmentation or replacement of tissue, uses silk fibroin and has a smooth surface and a porous surface. The smooth surface has a measured Sa value of less than approximately 0.1 μm when using Atomic Force Microscopy when samples of the repair device are fully hydrated by imaging through fluid in peak force tapping mode. A method of preparing such an implantable repair device includes preparing a gel from a fibroin solution in a mould, preparing a material by subjecting the gel to one or more steps of freezing and thawing the gel, and creating at least a porous surface on the device, wherein a portion of the mould is adapted to provide at least one smooth surface. | 09-18-2014 |
20110172394 | IMPLANTABLE MATERIAL FOR THE REPAIR, AUGMENTATION, OR REPLACEMENT OF BONE AND A METHOD FOR THE PREPARATION THEREOF - A method for the preparation of an implantable material for the repair, augmentation or replacement of bone from a fibroin solution, the method comprising the steps of: preparing a gel from the fibroin solution; preparing a material by subjecting the gel to one or more steps of freezing and thawing the gel, wherein the step of preparing the gel from the fibroin solution is performed in the presence of phosphate ions. The material may be treated with calcium ionstoform a fibroin-apatite. A further method comprises the step of treating the material with an isocyanate. The invention also extends to a method for the preparation of an implantable material, wherein a regenerated fibroin solution is used. Also, there is an implantable material and an implant. | 07-14-2011 |