| OPTINOSE AS Patent applications |
| Patent application number | Title | Published |
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| 20120090608 | DELIVERY DEVICES - A delivery device for and method of delivering substance, the delivery device comprising: a delivery outlet from which substance is in use delivered; a gas chamber containing a gas and being of reducible volume, wherein a reduction in the volume of the gas chamber to a predeterminable volume acts to pressurize the contained gas to a predeterminable pressure; a seal element disposed between the gas chamber and the delivery outlet; and an opening mechanism configured, on reduction of the volume of the gas chamber to a predeterminable volume, to open the seal element, whereupon a gas flow from the gas chamber acts to deliver substance from the delivery outlet. | 04-19-2012 |
| 20120073571 | NASAL DELIVERY DEVICE - A breath-actuated nasal delivery device, comprising: a mouthpiece through which a user in use exhales to actuate the delivery device; a nosepiece for fitting to a nostril of the user through which a substance is in use delivered; a substance supply unit actuatable to deliver a dose of a substance through the nosepiece; a loading unit operable to load the substance supply unit with an actuation force; and a release mechanism for enabling actuation of the substance supply unit in response to exhalation by the user through the mouthpiece; wherein the release mechanism comprises a locking unit which is movable: between a locking configuration in which the substance supply unit is locked in a non-actuated position when loaded by the loading unit and a release configuration in which the substance supply unit is actuatable by the loading unit, and a trigger member for releasing the locking unit from the locking configuration to the release configuration in response to exhalation by the user through the mouthpiece and thereby enabling actuation of the substance supply unit. | 03-29-2012 |
| 20120006323 | NASAL DEVICES - A nasal delivery device for and a method of delivering a substance, in particular one of a liquid, as a suspension or solution, or a powder containing a medicament, especially systemic or topical pharmaceuticals, or a vaccine to the nasal airway of a subject. | 01-12-2012 |
| 20110318345 | NASAL DELIVERY - substances and the nasal administration thereof, in particular as one of a liquid, as a suspension or solution, or a powder, to the nasal airway of a subject, in particular the posterior region of the nasal airway, and in particular the upper posterior region of the nasal airway, which includes the olfactory bulb, in particular in the treatment of neurological conditions and disorders. | 12-29-2011 |
| 20110259329 | DELIVERY DEVICES - A breath-actuated delivery device includes a mouthpiece through which a subject in use exhales, an air channel which is in fluid communication with the mouthpiece, and a flexible diaphragm which is disposed in the air channel. The diaphragm provides for at least a restricted air flow through the air channel until a predeterminable actuation pressure is developed in the mouthpiece, and, on generation of the predeterminable actuation pressure in the mouthpiece, provides for an air flow through the air channel. | 10-27-2011 |
| 20110126830 | DELIVERY DEVICES - A delivery device for delivering a metered amount of substance, the delivery device comprising: a mouthpiece ( | 06-02-2011 |
| 20110088690 | NASAL DELIVERY DEVICES - A nasal delivery device for and a method of delivering substance to a nasal airway of a subject, the nasal delivery device comprising : a mouthpiece ( | 04-21-2011 |
| 20110053827 | INTRANASAL ADMINISTRATION - Intranasal administration of proteins, such as insulin and insulin analogues, in particular immunogenic proteins to the upper posterior region of a nasal cavity of a subject, and in particular the olfactory bulb region. | 03-03-2011 |
| 20110023869 | DELIVERY DEVICES - A delivery device for delivering a metered amount of substance (L) in response to exhalation by a user, the delivery device comprising: a mouthpiece ( | 02-03-2011 |
| 20100300439 | NASAL DELIVERY DEVICES - A nasal delivery device for and method of delivering particulate substance to the nasal airway of a subject, the delivery device comprising: a body assembly ( | 12-02-2010 |
| 20100288275 | NASAL ADMINISTRATION - A delivery device for and method of delivering a powdered substance, in particular a triptan, such as sumatriptan, to the posterior region of a nasal cavity of a subject, in particular for the treatment of headaches, for example, cluster headaches and migraine, and neuropathic pain, the delivery device comprising: a nosepiece ( | 11-18-2010 |
| 20100282246 | NASAL DELIVERY - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece ( | 11-11-2010 |
| 20100057047 | DELIVERY DEVICE AND METHOD - A nasal delivery device for and method of delivering substance to the middle meatus in a nasal cavity of a subject in the treatment of a condition, in particular an inflammatory or infectious condition, thereof, the delivery device comprising: a nosepiece unit ( | 03-04-2010 |
| 20100051022 | DELIVERY DEVICE AND METHOD - A delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: at least one nosepiece unit ( | 03-04-2010 |
| 20100035805 | NON-AQUEOUS LIQUID FORMULATION FOR NASAL OR BUCCAL ADMINISTRATION - A formulation for administration to a nasal or buccal cavity of a subject which comprises a non-aqueous liquid environment, preferably an emollient oil base, and at least one active molecule, preferably a dopamine agonist and especially apomorphine, in solution or suspension therein, wherein in one embodiment the formulation has such a viscosity as to be delivered as a liquid jet from a spray pump which is capable of delivering an aerosol spray of an aqueous formulation. | 02-11-2010 |
| 20090320832 | NASAL DELIVERY - A delivery device for and method of delivering a dose of substance for systemic uptake to a nasal cavity of a subject, the delivery device comprising: a nosepiece unit for insertion into a nasal cavity of a subject and comprising an outlet unit which includes at least one nozzle for delivering substance for systemic uptake substantially only to surfaces in one or both of the anterior region and an anterior section of the posterior region of the nasal cavity of the subject; and a substance supply unit which is operable to deliver a dose of substance to the at least one nozzle. | 12-31-2009 |
| 20090314293 | NASAL DELIVERY - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece unit ( | 12-24-2009 |
| 20090304802 | NASAL DELIVERY - A sustained release nasal formulation for delivery to a nasal cavity of a subject, wherein the formulation provides for sustained release of a substance, in particular nitric oxide (NO), to nasal mucosa within the nasal cavity so as to provide one or both of a therapeutic effect and promote normal nasal function, and a nasal delivery device and method relating thereto. | 12-10-2009 |
| 20090293873 | POWDER DELIVERY DEVICES - A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising: a substance supply unit for supplying a dose of substance to be delivered to the nasal cavity of the subject, she substance supply unit including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the substance supply unit; and a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the substance supply unit and through which the subject in use exhales such as to entrain substance from the container chamber and deliver the same through the nosepiece, and at least one temperature modifier for reducing a temperature of the exhaled air flow such as to reduce the absolute humidity thereof. | 12-03-2009 |
| 20080289629 | Nasal Delivery Devices - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and moisture-mitigation means for mitigating an effect of moisture in an exhaled breath on the entrainment of substance from the container, which means are provided, for example, by providing the container in a replaceable container-containing member, by a pressure-sensitive valve which normally closes the fluid connection between the container chamber and the mouthpiece, and a temperature regulator upstream of the container chamber. | 11-27-2008 |
| 20080223363 | Nasal Delivery Devices - An exhalation breath-actuated nasal delivery device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece ( | 09-18-2008 |
