| ONCOTECH, INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20090280508 | Methods and Reagents for Preparing and Using Immunological Agents Specific for P-Glycoprotein - This invention relates to immunological reagents and methods specific for a mammalian, transmembrane protein termed Pgp, having a non-specific efflux pump activity established in the art as being a component of clinically-important multidrug resistance in cancer patients undergoing chemotherapy. The invention provides methods for developing and using immunological reagents specific for certain mutant forms of Pgp and for wild-type Pgp in a conformation associated with substrate binding or in the presence of ATP depleting agents. The invention also provides improved methods for identifying and characterizing anticancer compounds. | 11-12-2009 |
| 20080280768 | Reagents and Methods for Predicting Drug Resistance - The invention provides methods for prognosis, diagnosis, staging and determining disease progression in human cancer patients related to amplification levels of one or a plurality of genetic loci that are differentially amplified in chemotherapeutic drug resistant tumor cells. | 11-13-2008 |
