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OMT, Inc.

OMT, Inc. Patent applications
Patent application numberTitlePublished
20120090041Compositions and Methods for Inhibiting Endogenous Immunoglobulin Genes and Producing Transgenic Human Idiotype Antibodies - The invention relates to transgenic animals lacking endogenous Ig and capable of producing transgenic antibodies, as well as methods of making the same. The invention further relates to methods for producing transgenic antibodies in such animals, and transgenic antibodies so produced.04-12-2012
20100212035Compositions and Methods for Producing Transgenic Mammals Having Recombinant Immunoglobulin Loci - The invention provides methods for the production of transgenic animals comprising a recombinant Ig locus, as well as transgenic antibodies derived therefrom. The methods involve meganuclease cleavage-stimulated homologous recombination in mammalian embryos.08-19-2010
20090098134COMPOSITIONS AND METHODS FOR INHIBITING ENDOGENOUS IMMUNOGLOBULIN GENES AND PRODUCING TRANSGENIC HUMAN IDIOTYPE ANTIBODIES - The invention relates to transgenic animals lacking endogenous Ig and capable of producing transgenic antibodies, as well as methods of making the same. The invention further relates to methods for producing transgenic antibodies in such animals, and transgenic antibodies so produced.04-16-2009