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Old Dominion University Research Foundation

Old Dominion University Research Foundation Patent applications
Patent application numberTitlePublished
20120109263Medical Instrument for Delivery of High Voltage Pulses and Method of Delivering the Same - An instrument 05-03-2012
20120097539NANOPORE-BASED NANOPARTICLE TRANSLOCATION DEVICES - A nanoparticle translocation device includes a first reservoir having a first reservoir electrode, a second reservoir having a second reservoir electrode, and at least one nanopore providing fluid communication between the first and second reservoirs. The device also includes one or more inner electrode portions on an inner wall of the nanopore and one or more outer electrode portions disposed on an outer wall of the nanopore. The device further includes at least one DC voltage supply for selectively applying a DC voltage to each of the first reservoir electrode, the second reservoir electrode, and the outer electrode layer, where the inner electrode portions, the outer electrode portions, and the nanopore are in a substantially coaxial arrangement.04-26-2012
20120089209Method and System for Treating a Biological Target Region Using Pulsed Electromagnetic Radiation - A method of treating a patient is described herein. The method can include the steps of identifying a target that contains biological tissue and directing one or more pulses of electromagnetic radiation at the target. The pulses of electromagnetic radiation can cause a temperature increase per unit of time in the biological tissue. Additionally, the temperature increase per unit of time can cause the change in the cell function in the biological tissue and can be within a range of approximately one degree Celsius per second to approximately one degree Celsius per microsecond.04-12-2012
20120080313ELECTROOSMOTIC DEVICES - Electroosmotic (EO) devices are provided which are not subject to mechanical wear and tear and with no moving parts, and having improved flow rates and electrical properties. Atomic layer deposition can be used to prepare three electrical terminal active zeta potential modulated EO devices from porous membranes. First, second, and further thin layers of materials can be formed with the pores. Thus, embedded electrodes can be formed along the length of the pores. The zeta potential in the pores can be modified by use of a voltage potential applied the embedded electrode, thereby achieving active control of surface zeta potential within the pores and active control of flow through the pores.04-05-2012
20120035511SYSTEM AND METHODS OF TREATMENT USING ELECTROMAGNETIC ILLUMINATION - A method of inducing local cell death in patient tissue is provided. The method includes generating first and second radiation, conveying the radiation to a focusing element, and focusing the radiation on a target with the focusing element. A system for inducing local cell death in patient tissue is also provided. The system includes a power source for generating narrow-band and/or ultra-wideband radiation, and a focusing element for focusing the radiation on a target.02-09-2012
20120034410MULTIPLE WALLED NESTED COAXIAL NANOSTRUCTURES - Multiple walled nested coaxial nanostructures, methods for making multiple walled nested coaxial nanostructures, and devices incorporating the coaxial nanostructures are disclosed. The coaxial nanostructures include an inner nanostructure, a first outer nanotube disposed around the inner nanostructure, and a first annular channel between the inner nanostructure and the first outer nanotube. The coaxial nanostructures have extremely high aspect ratios, ranging from about 5 to about 1,200, or about 300 to about 1200.02-09-2012
20110314881Process for the Selective Production of Hydrocarbon Based Fuels from Algae Utilizing Water at Subcritical Conditions - Disclosed herein is the production of hydrocarbon based fuel from micro-organisms and algae that comprise algaenan without requiring prior removal of water, as well as the production of hydrocarbon based fuel directly from the algaenan itself. Also disclosed herein are feed material for the processes disclosed herein comprising modified algae and algaenan that selectively produce hydrocarbon of desired chain lengths, along with the process of modifying the algae and algaenan. Also disclosed herein is the production of both hydrocarbon and organic fertilizer from algae without the need to remove the water from the algae prior to processing.12-29-2011
20110311639Facile Route to the Synthesis of Resorcinarene Nanocapsules - Described is a direct method for the fabrication of resorcinarene nanocapsules by photopolymerization of compounds of formula (I), such as resorcinarene tetraalkene tetrathiol (RTATT), in the absence of any template or preorganization. Further, by varying the polymerization media, a variety of other polymeric architectures like lattices, fibrous networks, and nanoparticles were obtained. The morphology and structure were characterized by transmission electron microscopy, energy dispersive spectroscopy, scanning electron microscopy, dynamic light scattering, infrared and nuclear magnetic resonance spectroscopy. These morphologically distinct resorcinarene polymeric architectures contain residual thiol and ene functional groups offering potential functionalization opportunities.12-22-2011
20110306962Method and Device for Treatment of Conditions Aggravated by Amyloid Fibrils - A method and device for treating a condition aggravated by the presence of amyloid fibrils is disclosed. The method includes applying a plurality of ultra-short pulses to target tissue comprising amyloid fibrils. The plurality of ultra-short pulses produce an electric field in the target tissue sufficient to change a molecular structure of the amyloid fibrils without causing the death, destruction, or serious injury of healthy cells surrounding the target tissue. For example, the plurality of ultra-short pulses can be sufficient to change the molecular structure of amyloid fibrils without causing apoptosis or necrosis of surrounding cells. The ultra-short pulses can be applied using an electrode device or a wideband antenna. The ultra-short pulses can have a duration ranging from 1 ps to 10 ns, an amplitude ranging from 100 V to 1 MV, and can apply an electrical field to the target tissue ranging from 1 kV/cm to 1 MV/cm.12-15-2011
20110292208HIGH-RESOLUTION URBAN TRUE ORTHOIMAGE CREATION - A method, system, and computer readable medium for producing orthoimages of the images of a (typically) high-resolution imager of an urban area, the orthoimages of high buildings being imaged with improved accuracy by increasing constraint conditions on the building edges, such as perpendicularity, collinearity. These constraint conditions are merged into an orthorectification model for orthorectifying the images captured at a predetermined elevation, whether by airborne or spaceborne. Constraint conditions may be formed by the building edge points, such as corners, and may be used with a digital building model. Thus, an aspect of embodiments is that the constraint conditions may be directly formed from the building themselves. The higher the buildings, the more effective the constraint controls.12-01-2011
20110289830Production of Glycerol-Related Products from a High Temperature Reaction - Disclosed are processes for producing glycerol related products. One process comprises introducing a biomass and an alkylation reagent to a substantially oxygen free environment, hydrolyzing at a temperature at or above 200° C. one or more lipid glycerides in the biomass, methylating one or more fatty acids in the biomass with methyl groups from the alkylation reagent, wherein the hydrolyzing and methylating occur contemporaneously and separating resulting biodiesel and methylated glycerol-related products from a residue of the biomass by condensation.12-01-2011
20110288545Method and Device for Ablation of Cancer and Resistance to New Cancer Growth - Methods and devices designed to eliminate and/or ablate cancer or other abnormal growths of cells or tissues or eliminate and/or ablate cells or tissue with abnormal functions. In particular, using sub-microsecond electric pulses to treat cancer cells by, inter alia, inducing programmed cell death or other type of cell death. These methods and devices are expected to greatly improve the prevention, treatment and management of cancer by increasing the effectiveness of cancer treatments and development of resistance to new cancer growth.11-24-2011
20110184411SURGICAL TOOL FOR PECTUS BAR EXTRACTION - A pectus bar extraction tool for removing a pectus bar having posterior and anterior sides includes a handle, an engagement member fixed to and extending from the handle for extending from the anterior to the posterior sides of the pectus bar to engage the posterior side of the pectus bar, and a lever arm fixed to and extending from the handle opposite to the engagement member for engaging the pectus bar on the anterior side of the pectus bar. A system and method for removing a pectus bar are also disclosed.07-28-2011
20110003350SYSTEM AND METHOD FOR HIGH-VOLTAGE PULSE ASSISTED AGGREGATION OF ALGAE - A method and device for aggregating algae in an aqueous solution is disclosed. The method can include providing an algae feed comprising a liquid and algae dispersed therein. The algae feed can be aggregated by applying a nanosecond pulsed electric field to the algae feed. The nanosecond pulsed electric field can include a plurality of electric pulses having a pulse duration ranging from 1 to 1,000 nanoseconds. The method can also include separating an aggregated algae stream from the algae feed and feeding the aggregated algae stream to a lipid extraction operation.01-06-2011
20100286573SYSTEM AND METHODS OF TREATMENT USING ULTRA-WIDEBAND, HIGH POWERED FOCUSING EMITTERS - A method of inducing local hyperthermia in patient tissue is provided. The method includes generating ultra-wide-band radiation, conveying the ultra-wideband radiation to a focusing element, and focusing the ultra-wideband radiation on a target with the focusing element. A system for inducing local hyperthermia in patient tissue is also provided. The system includes a power source for generating ultra-wideband radiation, and a focusing element for focusing the ultra-wideband radiation on a target.11-11-2010
20100280513SYSTEM AND METHOD FOR APPLYING PLASMA SPARKS TO TISSUE - A pulse delivery system for producing a spark in tissue is disclosed. The system can include at least two electrodes having sharp surface features, where the at least two electrodes are electrically isolated from one another. The sharp features of the electrodes can be separated by a distance of about 2 to 20 mm. The system can also include a pulse generator for delivering pulsed voltage differences between the at least two electrodes. The pulsed voltage differences can producing a voltage difference ranging from about 2.5 kV to about 35 kV for a duration of about 50 ns to 3 μs. The system can include a controller for determining whether the plurality of pulsed voltage differences produced a spark between the at least two electrodes. A method of producing a spark in tissue for both therapeutic and cosmetic, i.e., non-therapeutic, applications is also disclosed.11-04-2010
20100278401WIDEBAND BIO-IMAGING SYSTEM AND RELATED METHODS - An imaging and recordation system is provided. The system includes a high-power, focusing antenna for illuminating biological tissue. The system further includes a power source for powering the antenna. The system further includes a data acquisition module, for recording the dielectric properties of tissues illuminated by the high-power, focusing antenna. The system illuminates the tissues using ultrashort electrical pulses.11-04-2010
20100211331DEVICE FOR MEASURING LOAD AND DEFLECTION OF MATERIALS - A system for measuring normal load and deflection of a material that includes a portable load deflection device and a method of using the same is disclosed. The system includes a support arm having a first end and a second end opposite said first end. The first end can be attached to a base surface. The support arm can provides at least three degrees of freedom of movement and includes at least one sensor for determining a position of the second end. A uniaxial load cell can be operably attached to the second end. The system can also include a processing system operable to receive position data and corresponding force data when the support arm is used to apply a non-normal compression force to the test surface. The data can be used to calculate normal force versus deflection data for the test surface.08-19-2010
20100031561Raceways for Cultivating Algae - A raceway for cultivating algae in a liquid medium, comprising one or more precipitators positioned along the raceway, and at which precipitators the algal biomass produced in the raceway is precipitated from the liquid medium and concentrated.02-11-2010
20090158638Direct Conversion of Biomass to Biodiesel Fuel - Disclosed is the direct conversion process for producing biodiesel from a biomass. The direct conversion process for producing biodiesel from a biomass comprises reacting a feed stock comprising a biomass and an alkylation reagent in a substantially oxygen free environment at a temperature sufficient to hydrolyze one or more lipid glycerides in the biomass and alkylated one or more fatty acids in the reaction. The process may comprise reacting a feed stock comprising an algal biomass and tetramethylammonium hydroxide in a substantially oxygen free environment at a temperature between 250° C. and 500° C. The direct conversion process for producing biodiesel may further comprise reacting oil containing lipid glycerides with an alkylation reagent at a sufficient temperature to esterify the oil. The fatty acid alkyl esters produced from the reacted feed stock are recovered. The recovered fatty acid alkyl esters, as an essential component of biodiesel, may be formulated into biodiesel.06-25-2009

Patent applications by Old Dominion University Research Foundation