| OKLAHOMA MEDICAL RESEARCH FOUNDATION Patent applications |
| Patent application number | Title | Published |
|---|
| 20120116685 | Methods, System, And Medium For Associating Rheumatoid Arthritis Subjects With Cardiovascular Disease - The present invention relates to a system and a medium for analyzing one or more analytes in rheumatoid arthritis subjects to determine whether the subject is at increased risk of diseases such as a cardiovascular disease, the subject's current cardiovascular disease burden, and the likelihood of cardiovascular disease progression in the subject. In addition, the present invention further provides methods for analyzing data to determine risk of cardiovascular disease, current cardiovascular disease burden, and the likelihood of cardiovascular disease progression in a rheumatoid arthritis subject. | 05-10-2012 |
| 20110137851 | BIOMARKERS AND METHODS FOR MEASURING AND MONITORING INFLAMMATORY DISEASE ACTIVITY - Biomarkers useful for diagnosing and assessing inflammatory disease are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. The biomarkers include at least two biomarkers selected from the DAIMRK group and the score is a disease activity index (DAI). | 06-09-2011 |
| 20110110954 | Anthrax compositions and methods of use and production - Compositions and methods effective for eliciting an immune response for preventing or reducing infection or improving clinical outcomes caused by | 05-12-2011 |
| 20100172926 | ANTHRAX COMPOSITIONS AND METHODS OF USE AND PRODUCTION - Compositions and methods effective for eliciting an immune response for preventing or reducing infection or improving clinical outcomes caused by | 07-08-2010 |
| 20090325167 | METHOD OF USING CYTOKINE ASSAY TO DIAGNOSE, TREAT, AND EVALUATE INFLAMMATORY AND AUTOIMMUNE DISEASES - The invention provides methods for diagnosing, treating, or evaluating inflammatory and autoimmune diseases by sampling peripheral blood, serum, plasma, tissue, cerebrospinal fluit, or other bodily fluids from a human subject having a suspected diagnosis. The sample is analyzed for the presence and amount of certain cytokines, which provides the diagnosis, prognosis or evaluation of therapeutic response. | 12-31-2009 |
| 20090214554 | TRUNCATED MEMAPSIN 2 COMPOSITIONS AND TREATMENTS - The present invention provides novel methods of reducing memapsin 2 β-secretase activity in a subject, decreasing levels of β-amyloid peptide in the brain of a subject, treating Alzheimer's disease and/or reducing the size and/or number of β-amyloid plaques in the brain of a subject. The methods may include the step of administering an effective amount of truncated memapsin 2 protein, anti-truncated memapsin 2 antibody, and/or nucleic acid encoding a truncated memapsin 2 protein or anti-truncated memapsin 2 antibody. The present invention also provides related pharmaceutical compositions and uses thereof. | 08-27-2009 |
| 20090176246 | ASSAY FOR MEASURING FACTOR VIIa-ANTITHROMBIN COMPLEXES - A method for determining the concentration of factor VIIa-antithrombin complexes is disclosed which has application to estimating the level of intravascular exposure of tissue factor, assessing patient risk for hypercoagulation or other coagulopathies, and monitoring patients for factor VIIa-antithrombin complexes over time which can reveal changes in risk for hypercoagulation or other coagulopathies and/or effectiveness of anticoagulant therapy. Antibodies suitable for use in an in vitro assay for determining the concentration of factor VIIa-antithrombin complexes and methods for making the same are also disclosed. | 07-09-2009 |
| 20080207527 | Bicyclic Compounds Which Inhibit Beta-Secretase Activity and Methods of Use Thereof - The present invention provides bicyclic beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease. | 08-28-2008 |
