| OHIO STATE UNIVERSITY RESEARCH FOUNDATION Patent applications |
| Patent application number | Title | Published |
| 20110251240 | Dosing Regimen of Flavopiridol for Treating Cancer - A dosing regimen comprising a therapeutically effective amount of flavopiridol or a pharmaceutically acceptable salt thereof optionally in combination with a pharmaceutically acceptable carrier suitable for bolus infusion and subsequently for infusion is disclosed and claimed. Also disclosed and claimed is a method of treating a variety of cancers in a patient comprising administering to said patient the dosing regimen of the invention. | 10-13-2011 |
| 20100060457 | ELONGATED TWIN FEED LINE RFID ANTENNA WITH DISTRIBUTED RADIATION PERTURBATIONS - An RFID antenna comprising an elongated structure existing along an axis that is long compared to the signal wavelength and including twin ribbon-like feed lines of electrically conductive material, the feed lines being in a common plane and being uniformly laterally spaced from one another, and a plurality of radiating perturbations associated with the feed lines at a plurality of locations spaced along the feed lines, at each location each feed line has its own individual perturbation or portion of a perturbation. | 03-11-2010 |
| 20100035849 | NOVEL METHYLENEDIOXY PHENOLIC COMPOUNDS AND THEIR USE TO TREAT DISEASE - The present invention provides novel methylenedioxy phenolic compounds and their derivatives, methods of making them and methods of using them to treat or prevent cardiovascular disease, vascular disease and/or inflammatory disease, as well as Type I and Type II Diabetes and Dyslipidemia patients at risk for hypertension, stroke, cardiovascular and renal disease. | 02-11-2010 |
| 20090326020 | COMPOUNDS FOR TREATMENT OF CANCER - Compounds according to formula (I) are disclosed | 12-31-2009 |
| 20090305423 | Methods for Monitoring Composition and Flavor Quality of Cheese Using a Rapid Spectroscopic Method - Methods for evaluating cheese comprising using a rapid extraction method and an IR spectra analysis of the cheese are disclosed. | 12-10-2009 |
| 20090252741 | HUMAN MONOCLONAL ANTI-CTLA4 ANTIBODIES IN CANCER TREATMENT - Although results from preclinical studies in animal models have proven the concept for use of anti-CTLA-4 antibodies in cancer immunotherapy, two major obstacles have hindered their successful application for human cancer therapy. First, the lack of in vitro correlates of the anti-tumor effect of the antibodies makes it difficult to screen for the most efficacious antibody by in vitro analysis. Second, significant autoimmune side-effects have been observed In a recent clinical trial. In order to address these two issues, we have generated human CTLA-4 gene knock-in mice and used them to compare a panel of anti-human CTLA-4 antibodies for their ability to induce tumor rejection and autoimmunity. Surprisingly, while all antibodies induced protection against cancer and demonstrated some autoimmune side effects, the antibody that induced the strongest protection also induced the least autoimmune side effects. These results demonstrate that autoimmune disease does not quantitatively correlate with cancer immunity. Our approach may be generally applicable to the development of human therapeutic antibodies. | 10-08-2009 |
| 20090143446 | THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, METHODS OF MAKING, AND USES THEREOF - Substituted thiazolidinone carboxylic acid amides and substituted thiazolidine carboxylic acid amides according to formulae (I) and (II) are disclosed | 06-04-2009 |
| 20080255213 | THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, AND SERINE AMIDES, INCLUDING POLYAMINE CONJUGATES THEREOF, AS SELECTIVE ANTI-CANCER AGENTS - Substituted thiazolidinone carboxylic acid amides and substituted thiazolidine carboxylic acid amides having a structure | 10-16-2008 |