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of Health and Human Services Office of Technology Transfer

Rockville, MD US

of Health and Human Services Office of Technology Transfer Patent applications
Patent application numberTitlePublished
20090263365Methods and compositions for transforming dendritic cells and activating cells - Recombinant dendritic cells are made by transforming a stem cell and differentiating the stem cell into a dendritic cell. The resulting dendritic cell is an antigen presenting cell which activates T cells against MHC class I-antigen targets. Kits, assays and therapeutics are based upon the activation of T cells by the recombinant dendritic cell. Cancer, viral infections and parasitic infections are all ameliorated by the recombinant dendritic cells, or corresponding activated T cells. Therapeutic compositions and pharmaceutical compositions are provided.10-22-2009