O2 MEDTECH, INC.
|O2 MEDTECH, INC. Patent applications|
|Patent application number||Title||Published|
|20120095305||Spectrophotometric Monitoring Of Multiple Layer Tissue Structures - Methods, systems, and related computer program products for the non-invasive spectrophotometric monitoring of a biological volume having multiple tissue layers are described. Aggregate absorption and scattering properties are measured for each of a plurality of predetermined source-detector separation distances along a surface of the biological volume, the measurement being based on a model of the biological volume as a single-layer, semi-infinite, homogeneous volume. A predetermined multi-layer tissue model is retrieved that characterizes a mathematical relationship among (a) absorption and scattering properties of each layer of a multi-layer tissue structure, and (b) aggregate absorption and scattering properties of the multi-layer tissue structure as would be measured at selected source-detector separation distances along a surface thereof. The measured aggregate absorption and scattering properties are processed in conjunction with the predetermined multi-layer tissue model to compute therefrom a deep-layer-specific absorption property corresponding to the relatively deep tissue layer.||04-19-2012|
|20110190613||HYBRID SPECTROPHOTOMETRIC MONITORING OF BIOLOGICAL CONSTITUENTS - Systems, methods, and related computer program products for non-invasive NIR spectrophotometric (NIRS) monitoring of total blood hemoglobin levels and/or other blood constituent levels based on a hybrid combination of phase modulation spectrophotometry (PMS) and continuous wave spectrophotometry (CWS) are described. PMS-based measurements including both amplitude and phase information used in the determination of a non-pulsatile component of an absorption property for each of at least three distinct wavelengths are processed to compute PMS-derived intermediate information at least partially representative of a scattering characteristic. CWS-based measurements including amplitude information is processed in conjunction with the PMS-derived intermediate information to compute a pulsatile component of the absorption property. A metric representative of at least one chromophore level, such as the total blood hemoglobin level, is computed from the pulsatile component of the absorption property at the at least three wavelengths and displayed on an output display.||08-04-2011|
|20110060197||NEAR INFRARED SPECTROPHOTOMETRY WITH ENHANCED SIGNAL TO NOISE PERFORMANCE - Methods, systems, and related computer program products for the non-invasive spectrophotometric monitoring of an optical property of a tissue volume are described. Multiple optical signals having different modulation frequencies are introduced into the tissue volume simultaneously and on a continuous basis throughout the monitoring session. Multiple optical signal portions incident upon each of a plurality of optical detectors are detected and separated based on their modulation frequency. Amplitude and phase signals corresponding to each optical signal portion are extracted and processed to determine the optical property of the tissue volume. In one preferred embodiment, a first optical detector includes an aperture having a central area, a first edge positioned nearer to a first optical source than the central area, and a second edge positioned farther from the first optical source than the central area. The first and second edges are each curved concavely toward the first optical source.||03-10-2011|
|20110046459||Non-Invasive Patient Monitoring Using Near Infrared Spectrophotometry - Methods, systems, and related computer program products for non-invasive spectrophotometric monitoring of an optical property of a medium are described. Respective light portions are propagated through respective at least partially non-overlapping subregions of the medium during each of a calibration interval and a subsequent monitoring interval. Detections of the light portions acquired during the calibration interval are processed to compute at least one algorithm compensation that causes a first result related to the optical property for the first subregion to be substantially equal to a second result related to the optical property for the second subregion. Subsequently, detections of respective light portions acquired during the monitoring interval are processed in conjunction with the at least one algorithm compensation to compute a monitoring result for the optical property. Advantages can include a reduction in the number of sources/detectors required and/or an obviation of symmetry requirements in source/detector layout.||02-24-2011|
|20100198029||Patient Monitoring Using Combination of Continuous Wave Spectrophotometry and Phase Modulation Spectrophotometry - Non-invasive spectrophotometric monitoring of oxygen saturation levels based on a combination of continuous wave spectrophotometry (CWS) and phase modulation spectrophotometry (PMS) is described. First information representative of absolute oxygen saturation levels in relatively shallow regions of a patient tissue volume are acquired from PMS-based monitoring thereof during a reference interval. Second information representative of non-absolute oxygen saturation levels in relatively deep regions of the tissue volume are acquired from CWS-based monitoring thereof during the reference interval. Based on the first and second information acquired during the reference interval, a mapping is automatically determined between the second information and estimated absolute oxygen saturation metrics for the relatively deep regions. On a continuing basis during a monitoring interval subsequent to the reference interval, the second information continuously acquired from CWS-based monitoring of the tissue volume are continuously mapped into estimated absolute oxygen saturation metrics, which are continuously displayed on a display output.||08-05-2010|
|20090234245||NON-INVASIVE MONITORING OF INTRACRANIAL PRESSURE - Methods, systems, and related computer program products for are described for non-invasive detection of intracranial pressure (ICP) variations in an intracranial compartment of a patient. Optical radiation is propagated transcranially into the intracranial compartment, and optical radiation that has migrated through at least a portion of the intracranial compartment and back out of the cranium is detected. At least one signal representative of the detected optical radiation is processed to extract therefrom at least one component signal that varies in time according to at least one of an intrinsic physiological oscillation and an externally driven oscillation in the patient. Examples of suitable intrinsic physiological oscillations include intrinsic respiratory and cardiac oscillations. Examples of suitable externally driven oscillations include ventilated respiratory oscillations and externally mechanically induced oscillations. The extracted component signal is then processed to generate an output signal representative of the ICP variations in the intracranial compartment.||09-17-2009|
Patent applications by O2 MEDTECH, INC.