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NYCOMED GmbH

NYCOMED GmbH Patent applications
Patent application numberTitlePublished
20120129817COMBINATION TREATMENT FOR DIABETES MELLITUS - The subject matter of this application is directed to combinations of (2R,4aR,10bR)-6-(2,6-Dimethoxy-pyridin-3-yl)-9-ethoxy-8-methoxy-1,2,3,4,4a,10b-hexahydrophenanthridin-2-ol with other active compounds for the treatment of diabetes mellitus type 2 and/or type 1.05-24-2012
20120090606 APPARATUS FOR THE AEROSOLIZATION OF LARGE VOLUMES OF DRY POWDER - The claimed subject matter relates to a device for dosing and aerosolization of aerosolizable material. The device comprises: a body with an aerosolization channel with a distal attachment portion connectable to a source of carrier gas which provides pressure pulses to the aerosolization channel; a proximal attachment portion for outputting aerosolized material and a reservoir for receiving aerosolizable material. The reservoir comprises walls and is connected in a gas-tight manner to the body and in fluid connection with the aerosolization channel. At least part of the walls of the device are self-exciting membranes that can be put into oscillation by the pressure pulses.04-19-2012
20120083512PHARMACEUTICAL PRODUCT FOR INJECTION - The claimed subject matter is related to a pharmaceutical product for injection comprising a container including a closure suitable for preparations for injection, the container containing an acid labile proton pump inhibitor, a salt thereof, a solvate of the acid labile proton pump inhibitor or a salt thereof, wherein the container and closure are made of material which essentially does not release zinc ions.04-05-2012
20110313005TOPICALLY APPLICABLE PHARMACEUTICAL PREPARATION - A topical pharmaceutical preparation for administering a slightly soluble PDE4 inhibitor is described. A surprisingly good systemic bioavailability is observed with this dosage form.12-22-2011
20110308975STABILIZED PHARMACEUTICAL PRODUCT - Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.12-22-2011
20110269750ROFLUMILAST FOR THE TREATMENT OF DIABETES MELLITUS - The application relates to specific combinations of Roflumilast and/or Roflumilast N-Oxide and a PPAR-agonist, as well as their use in the treatment of diabetes mellitus type 2.11-03-2011
20110257221NOVEL HYDROXY-6-HETEROARYLPHENANTHRIDINES AND THEIR USE AS PDE4 INHIBITORS - Compounds of the formula Ia*****10-20-2011
20110257169NOVEL HYDROXY-6-HETEROARYLPHENANTHRIDINES AND THEIR USE AS PDE4 INHIBITORS - Compounds of the formula Ia*****10-20-2011
20110251244Oral Dosage Form Containing A PDE 4 Inhibitor As An Active Ingredient And Polyvinylpyrrolidone As Excipient - Dosage forms for oral administration of a PDE 4 inhibitor whose solubility is slight are described. They contain PVP as binder.10-13-2011
20110218201NOVEL PYRAZOLONE-DERIVATIVES AND THEIR USE AS PDE-4 INHIBITORS - The compounds of Formula (I),09-08-2011
20110171303DOSAGE FORM CONTAINING (S)-PANTOPRAZOLE AS ACTIVE INGREDIENT - Dosage forms for oral administration of the magnesium salt of (S)-pantoprazole are described.07-14-2011
20110136803Triazolophthalazines - The compounds of formula (I)06-09-2011
20110108027FILTERING DEVICE, METHOD FOR FILTERING OF A FLUID, AND USE OF THE FILTERING DEVICE - A filtering device comprises a filtering means (05-12-2011
20110092471USE OF THE COMBINATION OF CICLESONIDE AND ANTIHISTAMINES FOR THE TREATMENT OF ALLERGIC RHINITIS - The subject matter of this application relates to the combination of ciclesonide with an antihistamine.04-21-2011
20110086827COMBINATION MEDICAMENT - The subject matter of this application relates to the combination of ciclesonide or an epimer thereof with R,R-formoterol or a salt, or a hydrate of a salt thereof.04-14-2011
20110064814STABLE PHARMACEUTICAL PRODUCTS - Provided herein is a stable pharmaceutical product comprising a dry powder inhalation device, and a pharmaceutical composition that comprises R,R-Formoterol L-tartrate salt, in particular crystalline R,R-formoterol L-tartrate; and ciclesonide.03-17-2011
20110060016Oral dosage form containing a pde 4 inhibitor as an active ingredient and polyvinylpyrrolidon as excipient - Disclosed is a method of treatment of COPD by oral administration of roflumilast.03-10-2011
20110044938TETRAHYDROBENZOTHIOPHENE DERIVATIVES - Compounds of a certain formula I, in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.02-24-2011
20110021479PYRROLOPYRIMIDINECARBOXAMIDES - The compounds of Formula (I),01-27-2011
20100317650IMIDAZOPYRIDINE DERIVATIVES USEFUL AS INOS INHIBITORS - The compounds of formula (I)12-16-2010
20100286140TRIAZOLOPHTHALAZINES - The compounds of formula I11-11-2010
20100247585STABILIZED PHARMACEUTICAL PRODUCT - Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.09-30-2010
20100234382COMPOSITION COMPRISING A PDE4 INHIBITOR AND A PDE5 INHIBITOR - The invention relates to the combined administration of a PDE4 inhibitor and a PDE5 inhibitor for the treatment of a disease in which phosphodiesterase 4 (PDE4) and/or phosphodiesterase 5 (PDE5) is detrimental.09-16-2010
20100190818Novel salts of 6-heterocycle substituted hexahydrophenanthridine derivatives - The invention relates to salts of 6-heteroaryl substituted hexahydrophenanthridine PDE4 inhibiting compounds, which can be used in the pharmaceutical industry for the production of pharmaceutical composition for use, e.g., in treatment of airway disorders.07-29-2010
20100179152Novel use for PDE5 inhibitors - The present invention is concerned with the use of PDE5 inhibitors in medicine.07-15-2010
20100179131Combination treatment for diabetes mellitus - The invention relates to combinations of (2R,4aR,10bR)-6-(2,6-Dimethoxy-pyridin-3-yl)-9-ethoxy-8-methoxy-1,2,3,4,4a,10b-hexahydrophenanthridine-2-ol with other active compounds for the treatment of diabetes mellitus type 2 and/or type 1.07-15-2010
20100120757PYRAZOLONE DERIVATIVES AS PDE4 INHIBITORS - The compounds of a certain formula 1,05-13-2010
201001207306-BENZYL-2,3,4,7-TETRAHYDRO-INDOLO [2,3-C] QUINOLINE COMPOUNDS USEFUL AS PDE5 INHIBITORS - The compounds of formula (I)05-13-2010
20100069392Combination of HMG-COA Reductase Inhibitors with Phosphodiesterase 4 Inhibitors for the Treatment of Inflammatory Pulmonary Disease - The invention relates to the combined use of a PDE4 inhibitor with a HMG-CoA reductase inhibitor for the preventive and curative treatment of an inflammatory pulmonary disease.03-18-2010
20100035913Novel guanidinyl-substituted hydroxy-6-phenylphenanthridines as effective phosphodiestrase (PDE) 4 inhibitors - The compounds of a certain formula (1),02-11-2010
20100034696Ciclesonide-containing sterile aqueous suspension - The present invention provides methods of manufacturing a sterile ciclesonide-containing aqueous suspension comprising the step of sterilization by autoclaving a ciclesonide-containing aqueous suspension.02-11-2010
20100022779Isotopically substituted proton pump inhibitors - The invention relates to compounds of formula 101-28-2010
20090297473Sulphonylpyrrole Hydrochloride Salts as Histone Deacetylases Inhibitors - Compounds of a certain formula 1,12-03-2009
20090270378NOVEL TETRAHYDROPYRIDOTHIOPHENES - Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and/or apoptosis inducing activity.10-29-2009
20090263353Novel Sulphonylpyrroles as Inhibitors of Hdac S Novel Sulphonylpyrroles - Compounds of a certain formula I,10-22-2009
20090239895Novel 3-thia-10-aza-phenanthrene derivatives - The compounds of formula I09-24-2009
20090215836Roflumilast for the Treatment of Pulmonary Hypertension - The invention relates to the use of Roflumilast, Roflumilast N-Oxide or a pharmaceutically acceptable salt of either for the treatment of pulmonary hypertension. The invention additionally relates to the use of Roflumilast, Roflumilast N-oxide or a pharmaceutically acceptable salt of either in combination with a PDE5 inhibitor or a pharmaceutically acceptable salt thereof for the treatment of pulmonary hypertension.08-27-2009
20090211577Device for Dosing and Dry Nebulization - The invention relates to a device 08-27-2009
20090209591Pharmaceutical product for injection - The present invention is related to a pharmaceutical product for injection comprising a container including a closure suitable for preparations for injection, the container containing an acid labile proton pump inhibitor, a salt thereof, a solvate of the acid labile proton pump inhibitor or a salt thereof, wherein the container and closure are made of material which essentially does not release zinc ions.08-20-2009
20090208571Dosage form containing pantoprazole as active ingredient - Dosage forms for the oral administration of the magnesium salt of pantoprazole are described.08-20-2009
20090171096Novel process for the preparation of roflumilast - The invention relates to novel processes for the preparation of high-purity roflumilast.07-02-2009
200901708923-Hydroxy-6-phenylphenanthridines as pde4 inhibitors - The compounds of formula I07-02-2009
20090170125Cellular assay method for identifying pkc-0 inhibitors - The invention relates to a method for investigating the modulating effect of a test substance on a PKCθ-dependent signal transduction pathway or for finding a PKCθ modulator in a human or animal cell, including the steps 07-02-2009
20090134211Method - The present invention relates to a method for the provision of clinical trial products in the context of clinical trials.05-28-2009
200901314482-(Piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors - The compounds of a certain formula (1),05-21-2009
20090131399Imidazopyridine Derivatives Useful as iNOS Inhibitors - The compounds of formula (I)05-21-2009
20090117074Sulfonylpyrroles as Histone Deacetylase Inhibitors - The invention relates to compounds of formula (I)05-07-2009
20090030065Use of Pde1c and Inhibitors Thereof - The present invention relates to the use of PDE1C as a novel target for the identification of compounds, which can be used for the treatment of pulmonary hypertension, fibrotic lung diseases or other fibrotic diseases outside the lung. The present invention further relates to the use of PDE1C inhibitors in the manufacture of pharmaceutical compositions for use in the therapy of those diseases.01-29-2009
20090020442Method for the Provision of Clinical Trial Products - The present invention relates to a method for the provision of clinical trial products and packaging of clinical trial products using RFID units in the context of clinical trials.01-22-2009
20090000615Device for Dosing and Dry Nebulization - The invention relates to a device (01-01-2009
200803190672-Hydroxy-6-phenylphenanthridines as PDE-4 inhibitors - The compounds of formula I12-25-2008
20080312225Triazolophthalazines - The compounds of formula (I)12-18-2008
20080280958Topically applicable pharmaceutical preparation - A topical pharmaceutical preparation for administering a slightly soluble PDE4 inhibitor is described. A surprisingly good systemic bioavailability is observed with this dosage form.11-13-2008
20080280855Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles - The invention relates to a process for the synthesis of compounds of the formula 1-a and compounds of the formula 1-b.11-13-2008
20080260749Novel Tetrahydropyridothiophenes - Compounds of a certain formula (I)10-23-2008
20080257339Aerosol Container - The present invention relates to an aerosol container with an RFID unit applied to a spacer connected to the base of the aerosol container.10-23-2008
20080255209Combination of a NSAID and a PDE-4 inhibitor - The invention relates to the combined use of a PDE4 inhibitor and a conventional NSAID in the treatment of an inflammatory disease and/or an inflammation-associated disorder while minimizing gastrointestinal side effects, such as gastric erosions and ulcer, which are frequently associated with the use of conventional NSAIDs. A preferred PDE 4 inhibitor for this combination is roflumilast or a derivative thereof. A preferred conventional NSAID for this combination is diclofenac or a derivative thereof.10-16-2008
20080226712Oral administration form for pyridin-2-ylmethylsulfinyl-1H benzimidazoles - The invention relates to an oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles and their salts, which comprises the active compound together with tablet disintegrants and is provided with a film coating customary per se for sustained-release compositions.09-18-2008
20080221111Combination of a Pd4 Inhibitor and a Tetrahydrobiopterin Derivative - The invention describes the use of a PDE4 inhibitor in combination with BH4 or a BH4 derivative for the prevention and/or treatment of respiratory diseases.09-11-2008
20080214536Amido-Substituted 6-Phenylphenanthridines - Compounds of a certain formula (I)09-04-2008

Patent applications by NYCOMED GmbH