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Novartis Forschungsstiftung, Zweigniederlassung Friedrich Mischer Institute for Biomedical Researc

Novartis Forschungsstiftung, Zweigniederlassung Friedrich Mischer Institute for Biomedical Researc Patent applications
Patent application numberTitlePublished
20110097731NOVEL MITOCHONDRIAL DYE - The present invention relates to the use of single-barrel genetically encoded GFP-based calcium indicator as an intramitochondrial dye and to nucleic acid molecules coding for said indicators, as well as to methods using said indicators. Examples of single-barrel genetically encoded GFP-based calcium indicator is a GCaMP, Case16 and/or Case12. In a particular embodiment, the single-barrel genetically encoded GFP-based calcium indicator is GCaMP2 or Case16.04-28-2011