NOVA Southeastern University Patent applications |
Patent application number | Title | Published |
20140314890 | COMBINATION ANTI-CANCER THERAPY - Discloses herein is a combination therapy for treating cancer by administration of a phycocyanin and a chemotherapeutic. | 10-23-2014 |
20140242177 | EPINEPHRINE NANOPARTICLES, METHODS OF FABRICATION THEREOF, AND METHODS FOR USE THEREOF FOR TREATMENT OF CONDITIONS RESPONSIVE TO EPINEPHRINE - The invention provides compositions including epinephrine nanoparticles and methods for therapeutic use of the compositions in the treatment of conditions responsive to epinephrine such as a cardiac event or an allergic reaction, particularly anaphylaxis. The epinephrine nanoparticles can be incorporated into orally-disintegrating and fast-disintegrating tablet pharmaceutical formulations and can significantly increase the sublingual bioavailability of epinephrine, and thereby reduce the epinephrine dose required. Additionally, the invention provides methods for fabrication of stabilized epinephrine nanoparticles for use in the described compositions. | 08-28-2014 |
20140214712 | METHOD FOR ADMITTING AN ADMISSIONS APPLICANT INTO AN ACADEMIC INSTITUTION - A method for admitting applicants into an academic institution can include the steps of: compiling a list of standardized test takers who have applied for admission to at least one academic institution, but have not received an offer of admission to any one of the at least one academic institutions; conditionally admitting selected ones of the test takers to an abbreviated academic program; subjecting the conditionally admitted test takers to at least one examination during the abbreviated academic program, each conditionally admitted test taker achieving a score on the at least one examination; and, admitting into the academic institution those conditionally admitted test takers who achieve a score on said at least one examination which satisfies an admissions criteria. | 07-31-2014 |
20140067707 | METHOD FOR ADMITTING AN ADMISSIONS APPLICANT INTO AN ACADEMIC INSTITUTION - A method for admitting applicants into an academic institution can include the steps of: compiling a list of standardized test takers who have applied for admission to at least one academic institution, but have not received an offer of admission to any one of the at least one academic institutions; conditionally admitting selected ones of the test takers to an abbreviated academic program; subjecting the conditionally admitted test takers to at least one examination during the abbreviated academic program, each conditionally admitted test taker achieving a score on the at least one examination; and, admitting into the academic institution those conditionally admitted test takers who achieve a score on said at least one examination which satisfies an admissions criteria. | 03-06-2014 |
20140059675 | BIOMETRIC AUTHENTICATION - A method of authenticating a user includes using at least one computer and connected scanner to obtain biometric measurements of a plurality of biometric parameters of the user. The parameters are stored as templates for comparison, as well as a sequence in which the plurality of biometric parameters are to be scanned in order to perform a valid authentication. Authentication is determined by comparing each biometric parameter submitted with the stored biometric templates, to determine if each biometric parameter matches a stored template. In addition, the sequence with which each matched template was presented is identified, and this sequence is compared with the stored sequence. If a predetermined number of biometric parameters match, and a predetermined number of elements in a sequence match, the user is authenticated. | 02-27-2014 |
20130302284 | MODULATING ONCOLYTIC VSV AND UPREGULATING RAE1 AND NUP98 WITH STATINS - Simvastatin is used to modulate VSV infection at the level of viral replication. Both lipid-lowering and pleiotropic cellular effects of simvastatin are exploited in the modulation. Simvastatin upregulates the expression of Rae1 and Nup98, therefore altering normal cellular mRNA distribution and reverting VSV's mRNA export block. Furthermore, simvastatin causes redistribution of Flotillin-1, which affects VSV replication/budding. Simvastatin is further used as a neoadjuvant for the selective modulatory control of live VSV oncolytic therapy. | 11-14-2013 |
20130274191 | METHODS AND COMPOSITIONS FOR THERAPEUTIC MODULATION OF ALDOSTERONE LEVELS IN HEART DISEASE - The disclosure describes the contribution of elevated levels of circulating alsosterone to heart disease and other hyperaldosteronic conditions. Since activation of beta-arrestin I (beta.arr-1) by the Angiotensin II (AngII) type 1 receptor (AT1R) mediates AngII-induced aldosterone production, beta-arrestin I (beta.arr-1) is a therapeutic target for heart disease. Specifically, the disclosure provides a beta.arr-1 protein fragment comprising the C-terminus of beta.arr-1 (beta.arr1ct; SEQ ID NO:3), compositions containing this protein fragment, and methods of using this protein fragment to reduce elevated levels of aldosterone in heart disease and other hyperaldosteronic conditions by inhibition of beta-arrestin (beta.arr-1). These compositions and methods are of therapeutic benefit in chronic heart failure and progression to heart failure after myocardial infarction (MI). Additionally, the invention provides an AngII peptide analog (SEQ ID NO:4), compositions containing this analog, and methods of using this analog for stimulation of beta.arr-1 activity and aldosterone production. | 10-17-2013 |
20120322884 | EPINEPHRINE NANOPARTICLES, METHODS OF FABRICATION THEREOF, AND METHODS FOR USE THEREOF FOR TREATMENT OF CONDITIONS RESPONSIVE TO EPINEPHRINE - The invention provides a composition including epinephrine nanoparticles and methods for therapeutic use of the composition in the treatment of conditions responsive to epinephrine such as a cardiac event or an allergic reaction, particularly anaphylaxis. The epinephrine nanoparticles can be incorporated into orally-disintegrating and fast-disintegrating tablet pharmaceutical formulations and can significantly increase the sublingual bioavailability of epinephrine, and thereby reduce the epinephrine dose required. Additionally, the invention provides methods for fabrication of stabilized epinephrine nanoparticles for use in the described compositions. | 12-20-2012 |
20120308548 | METHIONINE GAMMA LYASE-2-AMINOBUTYRATE DEAMINASE (MEGL-2ABD) AND THERAPEUTIC USES THEREOF - The invention relates to a methionine gamma lyase-2-aminobutyrate deaminase (MEGL-2ABD) enzyme and provides an isotopic assay for quantitatively measuring activity of the enzyme. The MEGL-2ABD is a therapeutic target for cancer, particularly in cancer stem cells and their lineages. The invention additionally provides a protein, MEGL-2ABD (SEQ ID NO:2), compositions/formulations containing this protein, and methods/assays for using this protein in therapeutic applications allowing progress toward prevention, diagnosis, treatment, and cure of cancer. | 12-06-2012 |
20120262672 | DOUBLE PASS DEVICE FOR RETINAL IMAGE QUALITY MEASUREMENT - An optical system for measuring retinal-image quality has a light system constructed and arranged to provide light to be directed onto a retina of a subject's eye, a detection system arranged to receive at least a portion of the light after being reflected or scattered back from the retina of the subject's eye, and an afocal optical system arranged in an optical path of the light between the light system and the detection system. The afocal optical system is constructed and arranged to correct a refractive error of the subject's eye. | 10-18-2012 |
20110236356 | METHODS OF ISOLATING AND USING STEM CELLS - Methods of isolating and using stem cells from neural crest, e.g. periodontal ligament, isolated stem cell and therapeutic cell cultures, and therapeutic applications for a variety of conditions. The cells and cell cultures are especially useful for autologous administration. | 09-29-2011 |
20110086868 | SPECIFIC INHIBITORS FOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTORS - The present application describes isoindoles and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful inhibitors of VEGFR. | 04-14-2011 |
20110082672 | STATISTICAL MODEL FOR PREDICTING FALLING IN HUMANS - Dependent variables believed to contribute to a likelihood of falling are analyzed using a latent class analysis. The dependent variables are biomedical factors, which may include, for example, arthritis, high blood pressure, diabetes, foot disorders, Parkinson's Disease, stroke, eye disorder, limb disorder, or proprioceptive disorder. Data pertaining to the biomedical factors is gathered from a population of individuals at risk of falling. Covariate data, including for example age and the number of prescriptions taken, is further analyzed against latent class data. For a particular group of at risk individuals, a set of five classes produced useful results broadly corresponding to groups representing individuals who have: good health; a range of diseases; Parkinson's Disease; arthritis; and high blood pressure. A probability of falling is determined, relative to the group of individuals with good health. | 04-07-2011 |
20100203481 | METHOD AND KIT FOR DELIVERING ENDODONTIC REGENERATIVE TREATMENT - The present invention provides novel methods and kits for removing unhealthy or necrotic pulp tissue from inside the root canals of a tooth, and to replace it with new vascularized tissue created by regenerative endodontic treatment. The present invention provides alternatives to current root canal therapies, as well as obturation of the root canal with dental materials. | 08-12-2010 |