Nottingham Trent University Patent applications |
Patent application number | Title | Published |
20160083795 | BIOMARKERS - The present invention relates to novel biomarkers for determining the Alzheimer's disease status of a subject, and to uses of novel panels of biomarkers. AD is currently clinically diagnosed using tests of cognitive function. Studies have shown that the accuracy of the clinical diagnosis is between 65 and 90% using cognitive techniques. The present invention provides a method of determining the Alzheimer' s disease status of a subject comprising providing a sample of material obtained from the subject and determining the expression level of one or more genes selected from the group consisting of: TUBB, NEAT1, CENPB, AA482221 and CPSF3 in the sample. | 03-24-2016 |
20150185219 | Biomarker SPAG5 - There has been a recent shift in cancer therapy from one size fits all to a personalized and tailored treatment for individual patients to increase efficiency and avoid unnecessary toxicity. This invention relates to a method of determining the prognosis and suitable treatment of cancer in a subject by measuring the level of expression of SPAG5. In particular, it relates to a method where high expression of SPAG5 in tumour cells correlates with aggressive tumours. | 07-02-2015 |
20140300978 | SURFACE PLASMON RESONANCE IN THIN FILMS - A thin film comprising a layer of dielectric material having electrically conductive inclusions, wherein the thin film has a first reflectivity due to surface plasmon resonance, and wherein the thin film is configured to provide one or more selected regions having a second reflectivity due to surface plasmon resonance. | 10-09-2014 |
20120066163 | TIME TO EVENT DATA ANALYSIS METHOD AND SYSTEM - A time to event data analysis method and system. The present invention relates to the analysis of data to identify relationships between the input data and one or more conditions. One method of analysing such data is by the use of neural networks which are non-linear statistical data modelling tools, the structure of which may be changed based on information that is passed through the network during a training phase. A known problem that affects neural networks is the issue of overtraining which arises in overcomplex or overspecified systems when the capacity of the network significantly exceeds the needed parameters. The present invention provides a method of analysing data, such as bioinformatics or pathology data, using a neural network with a constrained architecture and providing a continuous output that can be used in various contexts and systems including prediction of time to an event, such as a specified clinical event. | 03-15-2012 |
20110282819 | DATA ANALYSIS METHOD AND SYSTEM - The present invention relates to the analysis of data to identify relationships between the input data and one or more conditions. One method of analysing such data is by the use of neural networks which are non-linear statistical data modelling tools, the structure of which may be changed based on information that is passed through the network during a training phase. A known problem that affects neural networks is the issue of overtraining which arises in overcomplex or overspecified systems when the capacity of the network significantly exceeds the needed parameters. The present invention provides a method of analysing data using a neural network with a constrained architecture that mitigates the problems associated with the prior art. | 11-17-2011 |
20100254514 | DETECTION OF X-RAY SCATTERING - A radiation detecting apparatus includes a collimator and a detector, the collimator having a material for blocking radiation and a region that is a sector of an annulus or multiple regions in a configuration in the shape of a sector of an annulus for allowing transmission of the radiation. The detector is spaced a distance from the collimator such that when a radiation source and sample crystal material are positioned at suitable positions, the radiation is collimated by the collimator and contacts the sample a predetermined distance from the detector at multiple of locations corresponding to the region or regions of the collimator. The Bragg diffracted radiation from the crystal material at two or more and preferably all of the locations overlap at the detector. | 10-07-2010 |
20100216908 | Antimicrobial Polymer Nanocomposites - A method of preparing a polymer nanocomposite having antimicrobial properties, comprises (i) contacting a polymeric antimicrobial agent with a clay to form an organoclay; and (ii) subsequently dispersing the organoclay in a polymeric matrix. Polymer nanocomposites prepared by the method of the invention are not prone to leaching of the polymeric antimicrobial agent from the composite, and have many applications. | 08-26-2010 |