| NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE Patent applications |
| Patent application number | Title | Published |
| 20120039926 | Compositions and Methods for Modulating Immunogenic Responses by Activating Dendritic Cells - The conjugated peptide constructs described herein can be used to induce production of dendritic cells that generate cytokines. The vaccine-bearing dendritic cells can be administered to induce T cell mediated immune modulating responses. | 02-16-2012 |
| 20100047920 | DEVICE IMPROVING THE DETECTION OF A LIGAND - A device and method is disclosed for improving the detection of a ligand by a receptor by concentrating microbes by removing particulates from fluid-borne samples and/or causing selective aggregation of concentrated microbes. The device may be configured as a multipath valve capable purifying/concentrating a sample in one orientation and delivering the concentrated sample in another orientation. In one embodiment, the device includes a body that defines a plurality of chambers and pathways and supports a pathogen capture unit that houses a receptor that exhibits specificity for a ligand. In another embodiment, the capture unit houses a plurality of antibody coated generally spherical particles capable of binding to a ligand. | 02-25-2010 |
| 20090143457 | POLYCYCLIC COMPOUNDS FOR USE IN TREATING OCULAR NEURODEGENERATIVE DISEASES - Described herein are various compounds for treatment of ocular neurodegenerative diseases, including but not limited to glaucoma and diabetic retinopathy. The compounds described herein can act to attenuate and/or block calcium release from external neuronal environments as well as intracellular stores. | 06-04-2009 |