| NORTH CAROLINA STATE UNIVERSITY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120131710 | Pearlbush shrub named 'Blizzard' - ‘Blizzard’ is a new pearlbush plant particularly distinguished by its compact habit, smaller plant height and width, larger flower diameter, and larger genome size. | 05-24-2012 |
| 20120131709 | Weigela shrub named 'Sunset' - ‘Sunset’ is a new | 05-24-2012 |
| 20120118308 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 05-17-2012 |
| 20120117933 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 05-17-2012 |
| 20120077948 | Methods - The invention relates to a method of making a polypeptide comprising an orthogonal functional group, said orthogonal functional group being comprised by an aliphatic amino acid or amino acid derivative, said method comprising providing a host cell; providing a nucleic acid encoding the polypeptide of interest; providing a tRNA-tRNA synthetase pair orthogonal to said host cell; adding an amino acid or amino acid derivative comprising the orthogonal functional group of interest, wherein said amino acid or amino acid derivative is a substrate for said orthogonal tRNA synthetase, wherein said amino acid or amino acid derivative has an aliphatic carbon backbone; and incubating to allow incorporation of said amino acid or amino acid derivative into the polypeptide of interest via the orthogonal tRNA-tRNA synthetase pair. The invention also relates to certain amino acids, and to polypeptides comprising same. | 03-29-2012 |
| 20120075069 | REVERSIBLY DEFORMABLE AND MECHANICALLY TUNABLE FLUIDIC ANTENNAS - A method of manufacturing a fluidic structure is disclosed. A cavity that defines a shape of an element of the fluidic structure within a material is formed. The cavity is filled with liquid metal. The cavity is sealed. The fluidic structure behaves as an antenna. A fluidic antenna includes a material that defines a shape of the fluidic antenna by a cavity filled with liquid metal formed within the material, where the material further defines at least one mechanical property of the fluidic antenna. | 03-29-2012 |
| 20120034512 | LITHIUM ALLOY-CARBON COMPOSITE NANOFIBERS AND METHODS OF FABRICATION - A carbon/nanoparticle nanofiber includes a carbon base structure and a plurality of nanoparticles that include a lithium alloy or a lithium alloy precursor. One or more nanofibers may be formed into a nonwoven fabric. The fabric may be utilized as an electrode, such as for example in a battery. The carbon/nanoparticle composite nanofiber may be fabricated by forming a polymer/nanoparticle nanofiber, such as for example by a spinning technique, and carbonizing the polymer/nanoparticle nanofiber. | 02-09-2012 |
| 20120015020 | BIODEGRADABLE DRUG OR OTHER ACTIVE DELIVERY SYSTEM - A nonwoven fabric has been developed as a delivery system for drugs or other actives which includes biodegradable and biocompatible fibers with plant virus nanoparticles. The plant virus nanoparticles are pre-loaded with one or more actives. | 01-19-2012 |
| 20110294668 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES - Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator. | 12-01-2011 |
| 20110268911 | CONFORMAL COATING OF POLYMER FIBERS ON NONWOVEN SUBSTRATES - The present invention describes a novel process for the conformal coating of polymer fibers on nonwoven substrates. This process is based on the modification of polymer fiber surfaces by controlling the degree of etching and oxidation, which improves adhesion of initiators to the surface and facilitates subsequent conformal polymer grafting. The modified fiber surfaces render new functionalities to the surface, such as increasing hydrophilicity, attaching ligands or changing surface energy. The invention includes the modified polymer fibers produced by the process described herein. | 11-03-2011 |
| 20110183380 | POROUS, CARBOHYDRATE-BASED FOAM STRUCTURES AND ASSOCIATED METHODS - Porous, carbohydrate-based foam structures and associated methods are disclosed. According to an aspect, a method can include using a starch solution. The starch solution can be precipitated to form starch nanoparticles having a predefined void structure. | 07-28-2011 |
| 20110174322 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 07-21-2011 |
| 20110151053 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE - Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 06-23-2011 |
| 20110147764 | TRANSISTORS WITH A DIELECTRIC CHANNEL DEPLETION LAYER AND RELATED FABRICATION METHODS - A metal-insulator-semiconductor field-effect transistor (MISFET) includes a semiconductor layer with source and drain regions of a first conductivity type spaced apart therein. A channel region of a first conductivity type extends between the source and drain regions. A gate contact is on the channel region. A dielectric channel depletion layer is between the gate contact and the channel region. The dielectric channel depletion layer provides a net charge having the same polarity as the first conductivity type charge carriers, and which may deplete the first conductivity type charge carriers from an adjacent portion of the channel region when no voltage is applied to the gate contact. | 06-23-2011 |
| 20110081707 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR - Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 04-07-2011 |
| 20110079725 | APPARATUS AND METHOD TO ACHIEVE HIGH-RESOLUTION MICROSCOPY WITH NON-DIFFRACTING OR REFRACTING RADIATION - An imaging system employing a coded aperture mask having multiple pinholes is provided. The coded aperture mask is placed at a radiation source to pass the radiation through. The radiation impinges on, and passes through an object, which alters the radiation by absorption and/or scattering. Upon passing through the object, the radiation is detected at a detector plane to form an encoded image, which includes information on the absorption and/or scattering caused by the material and structural attributes of the object. The encoded image is decoded to provide a reconstructed image of the object. Because the coded aperture mask includes multiple pinholes, the radiation intensity is greater than a comparable system employing a single pinhole, thereby enabling a higher resolution. Further, the decoding of the encoded image can be performed to generate multiple images of the object at different distances from the detector plane. Methods and programs for operating the imaging system are also disclosed. | 04-07-2011 |
| 20110020900 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE - Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 01-27-2011 |
| 20110008292 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS ENCODING FRUCTO-OLIGOSACCHARIDE UTILIZATION COMPOUNDS AND USES THEREOF - Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed. | 01-13-2011 |
| 20110005499 | FUEL INJECTION DEVICE FOR AN INTERNAL COMBUSTION ENGINE, AND ASSOCIATED METHOD - A fuel injection device and associated method are provided. An injector body defines an axial bore and has a nozzle exit extending into the combustion chamber. The injector body receives fuel within the bore and channels the fuel through the nozzle exit into the combustion chamber. A flow rate control member is movably disposed within the injector body bore and is actuatable by a first actuator to move with respect to and to interact with the nozzle exit to control a flow rate of the channeled fuel. A pintle member is movably disposed within a flow rate control member bore and is actuatable by a second actuator, independently of the flow rate control member, to move with respect to the flow rate control member and to interact with the nozzle exit to control a spray angle of the channeled fuel. The flow rate and spray angle are thereby independently controllable. | 01-13-2011 |
| 20100331202 | NANOTUBE STRUCTURES HAVING A SURFACTANT BILAYER INNER WALL COATING - Nanotubes and nanotube array structures comprise (a) a nanotube having an inner wall portion; and (b) a bilayer coating formed on the inner wall portions, with the bilayer coating comprised of surfactants. A secondary compound such as a protein, peptide or nucleic acid may be associated with the bilayer coating. The structures are useful for, among other things, affinity purification, catalysis, and as biochips. | 12-30-2010 |
| 20100322859 | ORAL DRUG COMPLIANCE MONITORING USING MAGNETIC-FIELD SENSORS - A method to measure compliance with a pharmaceutical regimen, by the steps of: (a) ingesting a dose of a medication ( | 12-23-2010 |
| 20100279349 | NUCLEIC ACIDS ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR - Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 11-04-2010 |
| 20100261983 | IMPLANTABLE DEVICES FOR DYNAMIC MONITORING OF PHYSIOLOGICAL AND BIOLOGICAL PROPERTIES OF TUMORS - Biocompatible sensors configured for implantation include a first body in communication with a plurality of remote sensor bodies to detect physiological parameters in vivo. | 10-14-2010 |
| 20100205703 | Cercis plant named 'Ruby Falls' - ‘Ruby Falls’ is a new and distinct variety of redbud that has the following unique combination of desirable features that are outstanding in a new variety.
| 08-12-2010 |
| 20100205702 | Cercis plant named 'Merlot' - ‘Merlot’ is a new and distinct variety of redbud that has the following unique combination of desirable features that are outstanding in a new variety.
| 08-12-2010 |
| 20100190703 | PEPTIDES SPECIFIC FOR HUMAN BLOOD OUTGROWTH ENDOTHELIAL CELLS - Provided herein are compositions and methods for binding outgrowth endothelial cells (OEC). The compositions consist of peptide ligands capable of binding OEC with high affinity and specificity. The compositions of the invention include peptides set forth in SEQ ID NO: 1-38 and variants and derivatives thereof. Compositions also include the nucleotide sequences encoding the peptides of the invention. The compositions find use in methods for the isolation of OEC and for the recruitment and retention of OEC to sites of therapeutic interest. Methods for the identification and isolation of other peptides capable of binding OEC are also provided. | 07-29-2010 |
| 20100037942 | COMPOSITIONS AND PROCESSES FOR FORMING PHOTOVOLTAIC DEVICES - Photovoltaic cells, including silicon solar cells, and methods and compositions for making such photovoltaic cells are provided. A silicon substrate having an n-type silicon layer is provided with a silicon nitride layer, a reactive metal in contact with said silicon nitride layer, and a non-reactive metal in contact with the reactive metal. This assembly is fired to form a low Shottky barrier height contact comprised of metal nitride, and optionally metal silicide, on the silicon substrate, and a conductive metal electrode in contact with said low Shottky barrier height contact. The reactive metal may be titanium, zirconium, hafnium, vanadium, niobium, and tantalum, and combinations thereof, and the non-reactive metal may be silver, tin, bismuth, lead, antimony, arsenic, indium, zinc, germanium, nickel, phosphorus, gold, cadmium, berrylium, and combinations thereof. | 02-18-2010 |
| 20100037941 | COMPOSITIONS AND PROCESSES FOR FORMING PHOTOVOLTAIC DEVICES - Methods and compositions for making photovoltaic devices are provided. A metal that is reactive with silicon is placed in contact with the n-type silicon layer of a silicon substrate. The silicon substrate and reactive metal are fired to form a silicide contact to the n-type silicon layer. A conductive metal electrode is placed in contact with the silicide contact. A silicon solar cell made by such methods is also provided. | 02-18-2010 |
| 20100028945 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING STRESS-RELATED PROTEINS AND USES THEREFOR - Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 02-04-2010 |
| 20090270475 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES - Disclosure is provided for imidazole-phenyl derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same. | 10-29-2009 |
| 20090263438 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES - Disclosure is provided for imidazole-triazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same. | 10-22-2009 |
| 20090220969 | Identifying and quantifying small RNAs - One-step RT-PCR methods, compositions and kits for the detection and quantification of small RNAs in a sample are disclosed. The one-step RT-PCR approach involves polyadenylation of a small RNA followed by reverse transcription with a first primer containing a poly(T) sequence and at least two 3′ nucleotides complementary to the 3′ terminal end nucleotides of the small RNA, to produce a cDNA. This may be followed by PCR amplification using the same first primer as the revere primer and a second, forward primer in which a portion of its sequence is complementary to the 3′ terminal end of the cDNA. This may be then followed by detection and/or quantification of the amplified product. | 09-03-2009 |
| 20090205072 | ALTERATION OF TOBACCO ALKALOID CONTENT THROUGH MODIFICATION OF SPECIFIC CYTOCHROME P450 GENES - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 08-13-2009 |
| 20090198049 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS - A method of making a porphyrin is carried out by: (a) condensing (i) a 1,9-bis(N,N-)dialkylaminomethyl)dipyrromethane of Formula II: | 08-06-2009 |
| 20090183287 | Raspberry named 'Nantahala' - Linnaeus ‘Nantahala’ is a new and distinct variety of raspberry that has the following unique combination of desirable features that are outstanding in a new variety.
| 07-16-2009 |
| 20090178591 | Carbohydrate-gypsum composite - A carbohydrate-gypsum composite for use as a bonding agent in manufacturing gypsum construction materials is disclosed. The composite includes a carbohydrate substituted with sulfate moieties such as cellulose sulfate and a crystalline calcium sulfate dihydrate. The composite may be used in bonding paper cover sheets to a gypsum core to form a gypsum wallboard. Also disclosed are methods of making the composite and methods of making gypsum wallboard with the composite. | 07-16-2009 |
| 20090155913 | COMPOSITIONS COMPRISING PROMOTER SEQUENCES AND METHODS OF USE - Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided. | 06-18-2009 |
| 20090155213 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS AND USES THEREOF - NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided. | 06-18-2009 |
| 20090148673 | DEVICES CONTAINING CHIROPTICAL SWITCHING MATERIALS AND METHODS OF MAKING AND USING THE SAME - A polycarbodiimide polymer that is reversibly switchable between two distinct optical orientations is described. The polymer is useful in forming devices such as filters, storage media, actuators, and displays. Methods of making and using such polymers are also described. | 06-11-2009 |
| 20090143230 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES - Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator. | 06-04-2009 |
| 20090139990 | Portable Box for Carrying Items - A telescoping box includes a lid. The upper section of the box includes lids which are frictionally engagable therewith. The lids include speaker assemblies as part of each lid. The lids are removable and include connection points for audio signal sources such as MP3 players. | 06-04-2009 |
| 20090137795 | NEW ROUTE TO FORMYL-PORPHYRINS - A method of making a 5-formylporphyrin, comprises the steps of: condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin. Products and intermediates useful in such methods, along with methods of making such intermediates, are also described. | 05-28-2009 |
| 20090118356 | NEO-TANSHINLACTONE AND ANALOGS AS POTENT AND SELECTIVE ANTI-BREAST CANCER AGENTS - Compounds of Formulas I-II are described, | 05-07-2009 |
| 20090093021 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR - Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 04-09-2009 |
| 20090082576 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS - A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting group, with (ii) a metal salt under basic conditions to produce the metalloporphyrin. Products produced by such methods and intermediates useful for carrying out such methods are also described. | 03-26-2009 |
| 20090069558 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS - A method of making chlorins comprises the steps of reacting (e.g. condensing) a dipyrrin western half intermediate with an eastern half intermediate to form a tetrahydrobilene, and then cyclizing the tetrahydrobilene to form a chlorin. Intermediates including tetrahydrobilenes useful in such reactions are also described. | 03-12-2009 |
| 20090055981 | Buddleja plant named 'Blue Chip' - ‘Blue Chip’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety. 1. Moderate vigor resulting in compact growth habit. 2. Ease of asexual propagation using softwood or semi-hardwood cuttings. 3. Spreading growth habit with multi-branched stems. 4. Male sterility, and low female fertility and reduced seed set, resulting in less opportunity for seedlings to originate in the landscape setting. 5. Blue flower color. | 02-26-2009 |
| 20090055980 | Buddleja plant named 'Miss Ruby' - ‘Miss Ruby’ is a new and distinct variety of butterfly bush that has the following unique combination of desirable features that are outstanding in a new variety. 1. Moderate vigor resulting in compact growth habit. 2. Ease of asexual propagation using softwood or semi-hardwood cuttings. 3. Upright growth habit with flowers borne stiffly on upright shoots. 4. Low female fertility and reduced seed set, resulting in less opportunity for seedlings to originate in the landscape setting. 5. Bright pink flower color, unknown in any other butterfly bush variety. | 02-26-2009 |
| 20090023842 | PORPHYRIN AND CONDUCTIVE POLYMER COMPOSITIONS FOR USE IN SOLID-STATE ELECTRONIC DEVICES - Compositions comprising porphyrinic macrocycles and conjugated polymers such as polythiophene for use in organic electronic devices including solar cells are presented. Covalent linkage of a porphyrinic macrocycle to a polymer allows tuning of electronic and spectroscopic properties of conjugated polymers and can improve the heat stability of the system relative to a blended comparison. A composition comprising: at least one polymer comprising at least one porphyrinic macrocycle covalently linked to at least one conjugated polymer, wherein the porphyrinic macrocycle is metal-free is also presented. Inks can be formulated. Methods of making are provided. | 01-22-2009 |
| 20090005311 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS ENCODING FRUCTO-OLIGOSACCHARIDE UTILIZATION COMPOUNDS AND USES THEREOF - Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed. | 01-01-2009 |
| 20090005261 | PURIFICATION OF IMMUNOGLOBULINS USING AFFINITY CHROMATOGRAPHY AND PEPTIDE LIGANDS - An immunoglobulin binding peptide having the general formula, from amino terminus to carboxy terminus, of Z-R | 01-01-2009 |
| 20080293133 | Textiles for use in bioreactors for expansion and maintenance of cells - A bioreactor for three-dimensional culture of liver cells is disclosed. The device is characterized by the use of textile vasculatures. A model and method for optimizing vasculature parameters is also disclosed. Liver acinar structure and physiological parameters are mimicked by sandwiching cells in the space between the two innermost woven textile hollow fibers, and creating radial flow of media from an outer compartment, through the cell mass compartment, and to an inner compartment. The theoretical optimum hydraulic permeability for the two innermost semi-permeable membranes is determined based on physiological hepatic sinusoidal blood flow and pressures. Experimental studies using a flow rate and pressure monitoring systems in conjunction with phase-contrast velocity-encoded MRI confirm theoretical results. Novel woven vascular tubes with optimum hydraulic permeability are disclosed for culturing hepatocytes in the multi-coaxial bioreactor. | 11-27-2008 |
| 20080269501 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces - A method of making a phosphono-substituted dipyrromethane comprises reacting an aldehyde or acetal having at least one phosphono group substituted thereon with pyrrole to produce a phosphono-substituted dipyrromethane; and wherein the phosphono is selected from the group consisting of dialkyl phosphono, diaryl phosphono, and dialkylaryl phosphono. Additional methods, intermediates and products are also described. | 10-30-2008 |
| 20080233615 | NUCLEIC ACID ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR - Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 09-25-2008 |
| 20080221319 | METHOD OF MAKING PORPHYRINS - A method of making a compound of Formula I: | 09-11-2008 |
| 20080216256 | Heterobifunctional reactive dyes comprising a cysteamine linking group - The presently disclosed subject matter relates to heterobifunctional reactive dyes comprising nitrogen-containing heterocycles substituted by both halogen and vinyl sulfone moieties. In particular, the presently disclosed subject matter relates to reactive dye compounds comprising two or more halo-substituted, nitrogen-containing heterocycles and an asymmetric bridging group, wherein at least one of the two or more halo-substituted, nitrogen-containing heterocycles further comprises a vinyl sulfone substituent. In some embodiments, the bridging group has a structure based on cysteamine or cysteine. The heterobifunctional reactive dyes have high substrate affinity and can be applied to substrates, such as cotton fibers, under low salt conditions and with reduced dye material waste. | 09-11-2008 |
| 20080202541 | Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes - Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in | 08-28-2008 |
