| NORDIC BIOSCIENCE IMAGING A/S Patent applications |
| Patent application number | Title | Published |
|---|
| 20110142307 | VERTEBRAL FRACTURE PREDICTION - The risk of future fracture or deformity of vertebrae of a spine may be estimated by processing an image of at least one vertebra of a spine to compare data representing the appearance of the at least one vertebra with a statistical model of a corresponding part of a spine, the statistical model being formed from data representing images of spines for which information about the degree of fracture or deformity of each spine at a subsequent time is known, and deriving a measure of the similarity between the at least one vertebra of the spine and the model, which measure is representative of the likelihood that the spine will subsequently sustain a fracture or become deformed. | 06-16-2011 |
| 20110013819 | BREAST TISSUE DENSITY MEASURE - A method of processing a mammogram image to derive a value for a parameter useful in detecting differences in breast tissue in subsequent images of the same breast or relative to a control group of such images, said derived parameter being an aggregate probability score reflecting the probability of the image being a member of a predefined class of mammogram images, comprises computing for each of a multitude of pixels within a large region of interest within the image a pixel probability score assigned by a trained statistical classifier according to the probability of said pixel belonging to an image belonging to said class, said pixel probability being calculated on the basis of a selected plurality of features of said pixels, and computing said parameter by aggregating the pixel probability scores over said region of interest. Saud features may include the 3-jet of said pixels. | 01-20-2011 |
| 20100232671 | OPTIMISED REGION OF INTEREST SELECTION - A statistical framework for identifying regions of discrimination between two groups of imaged objects involves determining a weight map defining the regions of discrimination by minimizing the sample size required to discriminate the two groups in a numerical optimization scheme. | 09-16-2010 |
| 20100220907 | Pathology indicating measure related to cartilage structure and automatic quantification thereof - A method for the analysis of three dimensional scan data representing an articular cartilage is provided to extract a quantitative parameter indicative of joint pathology. A measure representative of cartilage homogeneity is derived from this three dimensional image data. The measured value is compared with similar measured values previously established in respect of healthy joints and/or joints characterised by a pathology. | 09-02-2010 |
| 20100135549 | VERTEBRAL FRACTURE PREDICTION - A method of processing data derived from an image of at least part of a spine is provided for estimating the risk of a future fracture in vertebrae of the spine. Position data relating to at least four neighbouring vertebrae of the spine is processed. The curvature of the spine at least two of the neighbouring vertebrae is calculated. The different curvature values are computed to obtain a value representative of the degree of irregularity in curvature of the spine and using the degree of irregularity, an estimate of the risk of a future fracture in vertebrae of the spine is provided. A higher degree of irregularity indicates a higher risk of future fracture. | 06-03-2010 |
| 20100093014 | SCREENING FOR BONE ANABOLIC FACTORS - A method for screening for modulators of the secretion by an osteoclast of a wnt or a wnt signal enhancer comprises exposing osteoclasts in culture to a compound to be screened, exposing a wnt sensitive detection system to conditioned medium from said osteoclast culture, and determining whether a wnt signal is present in said medium by assaying for wnt mediated activation of bone formation by osteoblasts or by wnt mediated activation of LRP5 and or LPR6 signalling in a cell by detection of β catenin or detection of translocation of disheveled, axin, or Frat1 to the cell membrane of said cell. | 04-15-2010 |
| 20090299769 | Prognostic osteoarthritis biomarkers - A computer based calculation of a prognostic index I of osteoarthritis based on biochemical and imaging based biomarkers a mathematical combination of said values, wherein a first imaging based biomarker is a measure of the quantity of a cartilage in a joint compartment, a second imaging based biomarker relating to the quality of said cartilage in said joint compartment, and wherein a value of said first biomarker indicative of a larger quantity of cartilage affects the index to make it predictive of more disease progression, and a value of said second biochemical marker indicative of a greater departure from the quality of disease free cartilage affects the index to make it predictive of more risk of disease progression, exemplified by | 12-03-2009 |
