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Nodality, Inc., A Delaware Corporation

Nodality, Inc., A Delaware Corporation Patent applications
Patent application numberTitlePublished
20100233733MULTIPLE MECHANISMS FOR MODULATION OF THE PI3 KINASE PATHWAY - An embodiment of the present invention is a method for measuring the post translational states and expression levels of proteins in the PI3K and/or mTor for use in diagnosis, prognosis and drug screening applications.09-16-2010
20100209929MULTIPLE MECHANISMS FOR MODULATION OF JAK/STAT ACTIVITY - An embodiment of the present invention is a method for subjecting a hematopoetic cell to a JAK/STAT inhibitor, determining the activity of gain-of-function mutations of a Jak family kinase, determining the expression levels and activity of JAK/STAT regulatory proteins, correlating the expression levels and the activity of JAK/STAT regulatory proteins with the activity of gain-of-function mutations of a Jak family kinase and with a response to the JAK/STAT inhibitor, and then classifying the cells. A further embodiment of the invention includes determining the clinical outcome based on the cell classification, determining a method of treatment, determining dosing and scheduling of at least one of the JAK/STAT inhibitors or other compounds.08-19-2010
20100105074HIGH THROUGHPUT FLOW CYTOMETRY SYSTEM AND METHOD - The invention provides systems, compositions, kits and methods for automated processing of biological samples and analysis using a flow cytometer.04-29-2010