| NEXT21 K.K. Patent applications |
| Patent application number | Title | Published |
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| 20120135955 | External Preparation Containing NSAIDs And Method For Producing The External Preparation - Disclosed is an external preparation containing nonsteroidal anti-inflammatory drugs (NSAIDs), which is suppressed in cytotoxicity induced by the NSAIDs. Also disclosed is a method for producing the external preparation. The present invention is based on the finding that skin disorders induced by nonsteroidal anti-inflammatory drugs (NSAIDs) can be suppressed when the NSAIDs form intermolecular compounds together with trehalose, which is an example of disaccharides. A disaccharide other than trehalose may be used therefor. | 05-31-2012 |
| 20120123542 | Artificial Bone Constituent Unit And Artificial Bone Constituent System - Provided are an artificial bone constructing unit which is capable of being built into a free shape according to build-up design, and effectively guiding bone replacement, and an artificial bone system. Specifically disclosed are an artificial bone constructing unit and an artificial bone constructing system, wherein in principal, the artificial bone constructing unit which constructs an artificial bone is so made into a block shape that when blocks are assembled, continuous holes through a plurality of blocks are formed. | 05-17-2012 |
| 20120122949 | ULTRA-HIGH STRENGTH INJECTABLE HYDROGEL AND PROCESS FOR PRODUCING THE SAME | 05-17-2012 |
| 20120097169 | Resin Product For Medical Use And Respiration-Assisting Tube - Disclosed is a respiration-assisting tube whereby tissue damages in vivo can be prevented and, as a result, inflammatory reactions and infections can be avoided. The respiration-assisting tube is developed based on the finding that adhesion of cells to a respiration-assisting tube can be inhibited by coating the respiration-assisting tube with a polymer containing 2-methacryloyloxyethyl phosphorylcholine (MPC). Also, the respiration-assisting tube is developed based on the finding that, by coating a respiration-assisting tube with a polymer containing MPC, mucosa peeling and tissue damages, which occur after using the respiration-assisting tube, can be prevented and, as a result, inflammatory reactions can be avoided. | 04-26-2012 |
| 20110301116 | NSAIDS-INDUCED GASTROINTESTINAL MUCOSAL DISORDER ALLEVIATOR AND MANUFACTURING METHOD THEREOF - [Problems] The object of the present invention is to provide a Medical Drugs which reduce damage of gastrointestinal mucosal induced by NSAIDs. | 12-08-2011 |
| 20110183000 | ARTIFICIAL BONE MATERIAL HAVING CONTROLLED CALCIUM ION ELUTION - Disclosed is an artificial bone material having controlled calcium ion elution, which does not induce cytotoxicity or any inflammatory response. It is found that the elution of a calcium ion from an artificial bone material for transplantation which contains a calcium-containing substance can be prevented effectively by subjecting the carrier to a surface treatment or adding a surface-treating agent to the carrier. It is also found that the induction of cytotoxicity can be prevented and the induction of an inflammatory response can also be prevented by using the above-mentioned carrier having controlled calcium ion elution. | 07-28-2011 |
| 20110166672 | BONE DEFECT FILLER NOT ADSORBING BONE GROWTH FACTOR AND NOT INHIBITING THE ACTIVITY OF THE SAME - An object of the invention is to provide a bone filling material capable of promoting the bone regeneration effect of a growth factor such as platelet rich plasma (PRP). | 07-07-2011 |
| 20100262259 | PROCESS FOR PRODUCING BONE GRAFTING MATERIAL, BONE GRAFTING MATERIAL, THREE-DIMENSIONAL SUPPORT FOR CELL CULTURE, AND SEPARATION SUPPORT FOR CHROMATOGRAPHY - A novel method for producing a bone filling material is provided. The method comprises the steps of: (a) kneading ingredient comprising calcium-based material and material comprising binder; (b) molding a predetermined shape of the mixture obtained in step (a) with an injection molding machine having a mold; (c) removing the binder contained in the mold formed in step (b) (i.e., degreasing) to obtain a degreased body; (d) and heating and sintering the degreased body obtained in step (c) to obtain a sintered body. | 10-14-2010 |
| 20100227804 | GEL-FORMING COMPOSITION FOR MEDICAL USE, ADMINISTRATION DEVICE FOR THE COMPOSITION, AND DRUG RELEASE CONTROLLING CARRIER - It is an object of the present invention to provide a gel-forming composition which permits on-site administration and can form a gel exhibiting prescribed strength and sustained drug release, devices for the administration thereof, and a kit for medical use. A gel-forming composition which is composed of the first composition comprising a drug, a first gelling agent represented by the general formula (I) and the like, and the first diluent and the second composition comprising the second gelling agent represented by the general formula (I) and the like and the second diluent; and application devices and kits for medical use, which can hold the gel-forming composition. X | 09-09-2010 |
| 20100069455 | BONE MODEL, BONE FILLER AND PROCESS FOR PRODUCING BONE FILLER - A method for producing a bone filler basically comprising: a bone model producing step (step 1) for producing a bone model; a figure forming material filling step (step 2) for filling a figure forming material into a bone defect site of the bone model obtained in the bone model producing step; and a bone filler producing step (step 3) for producing a bone filler which is to be filled in a bone defect site based on the figure forming material filled in the bone defect site of the bone model in the figure forming material filling step. | 03-18-2010 |
| 20100035837 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR VASOCONSTRICTION - An object of the present invention is to provide an agent for treating or preventing vasospasm. An object of the present invention is to provide an agent for treating or preventing cerebral vasospasm as well as arterial vasospasm. Further, an object of the present invention is to provide an agent for treating or preventing cerebral ischemia and cerebral infarction. | 02-11-2010 |
| 20100003301 | Bone Defect Filler, Release-Controlled Carrier, And Their Production Methods - A bone filling material having controlled release of a pharmaceutical agent such as a growth factor, and a drug release controlling carrier having controlled release of a pharmaceutical agent is provided by inactivating a functional group which can strongly bind to the pharmaceutical agent of the bone filling material with a blocking agent. The bone filling material and the drug release controlling carrier of the present invention comprises: a calcium-based material such as hydroxyapatite, carbonate apatite, fluorapatite, chlorapatite, β-TCP, and α-TCP; a blocking agent of the calcium-based material such as serine and dextran; and a pharmaceutical agent. | 01-07-2010 |
| 20090298033 | FIGURE-FORMING COMPOSITION, PROCESS FOR PRODUCTION OF FIGURES IN THREE DIMENSIONS BY USING THE COMPOSITION AND PROCESS FOR PRODUCTION OF THREE-DIMENSIONAL STRUCTURES - It is an object of the present invention to provide a figure-forming composition which enables the initiation of hardening even with a small amount of water and can attain a prescribed hardness, and which is suitable particularly for the production of three-dimensional living body models for surgical training by a rapid prototype process; and provide a three dimensional figure and a three-dimensional structure which are formed by using the composition. The figure-forming composition, for example, comprises a calcium-based material such as hemihydrate gypsum and polyvinyl alcohol resin, wherein the content of the polyvinyl alcohol resin is 2 to 20 weight parts when the total weight of the calcium-based material and the polyvinyl alcohol resin is 100 weight parts. | 12-03-2009 |
