| NATIONAL UNIVERSITY OF IRELAND, GALWAY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120109179 | Intravasculature Devices and Balloons for Use Therewith - An inflatable device ( | 05-03-2012 |
| 20120101007 | SILVER NANOPLATES - A sensor for detecting of an analyte in a solution phase comprises a plurality of functionalised silver nanoplates wherein a functionalising agent is directly bonded to the surfaces of the nanoplates. The nanoplates provide a detectable wavelength shift change in their local surface plasmon resonance spectrum in response to the binding of an analyte. Two or more of the nanoplates may be electromagnetically coupled. | 04-26-2012 |
| 20120095441 | STEM CELL DELIVERY DEVICE FOR ORTHOBIOLOGICS APPLICATIONS - A method and apparatus for thawing and delivery of cryogenically frozen biological material, such as stem cells includes a housing for receiving a pouch of frozen cells, a heating element against which the pouch is placed for applying defrosting heat to the pouch, and a squeezing apparatus for applying a squeezing force to the pouch after or upon thawing of the cells. The squeezing force may be applied by a roller pressing the pouch against the heating element, which forces the thawed cells from a needle or tube connected to the housing and/or to the pouch. A rechargeable battery in the housing supplies power to the heating element and the squeezing apparatus. | 04-19-2012 |
| 20120040906 | PROTEIN TARGETS IN DISEASE - MicroRNAs have been shown to be critically involved in control of cell survival and cell death decisions. By identifying microRNAs implicated in Endoplasmic Reticulum stress-induced cardiomyocyte apoptosis, it is envisaged that protein targets involved in same can be identified through specifically selected microRNAs. The microRNAs targeted are miR-351, miR-322, miR-125, miR-424 and miR-7a. Furthermore, the potential application of these identified proteins in the treatment of cardiovascular disease, in particular congestive heart failure, is disclosed. | 02-16-2012 |
| 20110311969 | Diagnostic Kit for Aspergillus Fumigatus Species - The use of the Ayg1 gene or an RNA transcript of the Ayg1 gene or fragments thereof as target regions in a diagnostic assay for the eukaryotic organism | 12-22-2011 |
| 20110276066 | Multichannel collagen nerve conduit for nerve repair - The present invention relates to the fabrication of multichannel nerve conduits for use in the repair of nerve injury. In particular, the invention relates to collagen multichannel nerve conduits which are suitable for use in repair of peripheral nerves. | 11-10-2011 |
| 20110238154 | Intravascular Treatment Device - A collapsible treatment device ( | 09-29-2011 |
| 20110217750 | Dendrimers and Dendrimer Applications - An activatable functionalised N | 09-08-2011 |
| 20110200552 | CYTOKINE DESIGN - The present invention relates to novel cytokines, which have a modified selectivity/specificity for their cognate receptors. In particular, the invention relates to a variant TRAIL protein, which has superior selectivity for the death receptor 4 (TRAIL-RI) over the death receptor 5 (TRAIL-R2). In addition, the invention relates to a variant TRAIL protein which exhibits superior selectivity for the death receptor 4 (TRAIL-R1) over the decoy receptors DcR1 (TRAIL-R3) and DcR2 (TRAIL-R4). | 08-18-2011 |
| 20110165265 | TRAIL VARIANTS FOR TREATING CANCER - The present invention relates to the use of a mutant TRAIL protein to treat various cancers in mammals. The invention provides a variant TRAIL protein, which has superior selectivity for the death receptor 5, for treating a mammal diagnosed with cancer. | 07-07-2011 |
| 20110064408 | OPTICAL SIGNAL PROCESSING - A central terminal for an optical communications network, comprises a light source, an optical splitter for separating light from said source into first and second signals, each being of the same wavelength, a modulator for encoding said first signal received from said splitter, a first output port coupled to said modulator for outputting said encoded first signal, and a second output port coupled to said splitter for outputting said second signal as an unencoded second signal. An endpoint terminal and method of communication are also disclosed. | 03-17-2011 |
| 20100310528 | Vector System for Site-Specific Integration - The integration system comprises at least one vector capable of expressing at least one exogenous gene, the vector comprising a coding sequence for an attP gene region and a coding sequence for at least one therapeutic molecule and an integrase. The integration system has an application in bacterial metabolic engineering and in gene therapy. | 12-09-2010 |
| 20100299717 | System for Annotation-Based Access Control - A system for annotation-based access control stores a network of interconnected data entities including Person, Resource and Policy entities, each Resource entity designated as being owned by a Person entity. The system enables a user to: define Annotations and to associate the Annotations with stored entities, each Annotation comprising terms defining the sharing of a Resource with Person entities; define Policies having associated Annotation(s); define Actions for each Policy, an action being performed on a Resource; and assign a Policy including an Annotation referring to a Person, a Person Annotation, to selected Resources. The system responds to a request from a user associated with a Person entity to perform an Action on a Resource if the Person satisfies Policies assigned to the Resource i.e. if a Resource is assigned a Policy having a Person Annotation and the Person entity has an Annotation corresponding to the Person Annotation. | 11-25-2010 |
| 20100150877 | Osteopontin for the Prediction and Treatment of Cardiovascular Diseases - Osteopontin for the prediction and treatment of cardiovascular diseases The present invention relates to the use of endothelial progenitor cells (EPCs) and osteopontin for the treatment of cardiovascular diseases or complications. The invention also relates to the use of EPC osteopontin levels as a marker of the risk of the development of these cardiovascular complications. In particular, the invention provides compositions and methods based on osteopontin and the genes encoding osteopontin. | 06-17-2010 |
| 20100143910 | NUCLEIC ACIDS PROBES FOR DETECTION OF YEAST AND FUNGAL SPECIES - The present invention use of to a portion of the RPS7 gene or its corresponding mRNA in a diagnostic assay for fungal and yeast species and sequences for use in such assays and methods. | 06-10-2010 |
| 20100137990 | Porous Substrates for Implantation - A porous substrate or implant for implantation into a human or animal body constructed from a structural material and having one or more regions which when implanted are subjected to a relatively lower mechanical loading. The region(s) are constructed with lesser mechanical strength by having a lesser amount of structural material in said region(s) relative to other regions. This is achieved by controlling pore volume fraction in the regions. A spacer is adapted to define an open-cell pore network by taking a model of the required porous structure, and creating the spacer to represent the required porous structure using three-dimensional modelling. Material to form the substrate about the spacer in infiltrated the scaffold structure formed. | 06-03-2010 |
| 20100119504 | Marker Sequences for Labour - The invention relates to markers which find use in the diagnosis of labour or pre-term labour, to assays comprising such markers, to methods of identifying therapeutic agents which can prolong pregnancy, using these markers and to methods of treatment of pre-term labour, methods of prolonging gestation, or methods of suppressing labour contractility based on the markers. | 05-13-2010 |
| 20100062038 | Markers, Antibodies and Recombinant scFvs for Mesenchymal Stem Cell Sub-populations and Osteoclasts - Abstract Markers, antibodies and recombinant scFvs for Mesenchymal Stem Cell sub-populations and osteoclasts. The present invention relates to specific epitopes of surface membrane bound glycoproteins expressed by mesenchymal stem cells and pre-osteoclasts and relates to antibodies such as monoclonal antibodies and recombinant scFv or fragments thereof, raised to the particular epitope and their use in identifying, isolating, and characterization of mesenchymal stem cell sub-populations such as that termed “Stromal Progenitor Cells” (SPCs) in bone marrow and identifying, isolating, and characterization of pre-osteoclasts in peripheral blood. By binding to a specific epitope on the cell surface, limbin/EVC-2 detection and separation by conventional cell sorting methodologies are facilitated. | 03-11-2010 |
| 20090306932 | Similarity index: a rapid classification method for multivariate data arrays - Similarity Index: a rapid classification method for multivariate data arrays The present invention is directed to a method of determining the similarity between a first multivariate data set and a second multivariate data set. The method is versatile and can be applied to a number of different multivariate data sets, for example, a spectroscopy multivariate data set. In particular, the method may be applied to rapidly assess the similarity between fluorescence spectroscopy multivariate data sets. The method comprises the steps of representing the data of a first and a second multivariate data set in matrix form to yield a multivariate data matrix, wherein each multivariate data matrix has the same dimensions. Subsequently, the magnitude of an additive and subtractive combination of each multivariate data matrix is calculated. The concept of a penalty parameter is introduced to set a detectable limit of variance between said first multivariate data set and said second multivariate data set. The penalty parameter is ascribed a value and is used in combination with the magnitude of an additive and subtractive combination of each multivariate data matrix to determine a similarity value. The determined similarity value indicates the variance between said first multivariate data set and said second multivariate data set. | 12-10-2009 |
| 20090246764 | Method for the detection of group B Streptococcus (GBS) (Streptococcus agalactiae) in mammals - A method for the detection of all strains of Group B Streptococcus (GBS) ( | 10-01-2009 |
| 20090140697 | BATTERY CHARGER AND METHOD - The present invention relates to a method for compensating for temperature effects in a pulsed battery-charging scheme with an average charging current less than the root-mean-square (rms) current. The method comprises varying the ratio of the average charging current to rms current as a function of the battery ambient temperature. The method may also comprise varying an upper threshold charging voltage as a function of the battery ambient temperature. | 06-04-2009 |
| 20090037220 | Portable medical monitoring and diagnostic system - A patient care distribution and management system is provided. The system allows for the seamless roaming of a patient within a particular medical facility or between medical facilities. The system includes body area network (BAN) management agents which process data within specified parts of a defined operational remit of a medical facility, a BAN hub agent associated with each patient that communicates with a BAN management agent and stores patient data delivered thereto by medical telemetry monitor diagnostic devices (MTMDDs) connected to each patient. The essential feature of the system is that the BAN hub agent has relatively little processing power compared to the BAN management agent which feeds it with patient monitoring rules to monitor the patient condition and to enable the BAN hub agent to set off alarms etc. as required. | 02-05-2009 |
| 20080205712 | Separating Directional Lighting Variability in Statistical Face Modelling Based on Texture Space Decomposition - A technique for determining a characteristic of a face or certain other object within a scene captured in a digital image including acquiring an image and applying a linear texture model that is constructed based on a training data set and that includes a class of objects including a first subset of model components that exhibit a dependency on directional lighting variations and a second subset of model components which are independent of directional lighting variations. A fit of the model to the face or certain other object is obtained including adjusting one or more individual values of one or more of the model components of the linear texture model. Based on the obtained fit of the model to the face or certain other object in the scene, a characteristic of the face or certain other object is determined. | 08-28-2008 |
