National University Corporation Hokkaido Universit Patent applications |
Patent application number | Title | Published |
20130004936 | SUPERCOOLING PROMOTING AGENT - The present invention discloses a supercooling promoting agent comprising a tannin for producing practical water which does not freeze. As the tannin, a hydrolyzable tannin such as 2,3,6-tri-O-galloyl-α,β-D-hamamelose, 1,2,6-tri-O-galloyl-β-D-glucose, and a vitrification liquid, each of which contains the supercooling promoting agent are useful as a solution or the like for storing a biological material at low temperature. | 01-03-2013 |
20120208219 | METHOD FOR ASSAYING CHOLESTEROL IN ApoE-CONTAINING HDL - This invention provides a method for separately or simultaneously quantifying cholesterol in a total amount of HDL-C, cholesterol in an HDL subfraction of apoE-containing HDL-C, and cholesterol in an HDL subfraction of apoE-deficient HDL-C. The method comprises enzymatically and separately quantifying cholesterol in apoE-containing HDL and cholesterol in apoE-deficient HDL by adding a surfactant selected from the group consisting of a surfactant with an apoE-containing HDL response rate/apoE-deficient HDL response rate ratio of 0.7 to less than 1.3, a surfactant with an apoE-containing HDL response rate/apoE-deficient HDL response rate ratio of less than 0.7, and a surfactant with an apoE-containing HDL response rate/apoE-deficient HDL response rate ratio of 1.3 or more to a test sample, allowing cholesterol esterase and cholesterol oxidase to react therewith, and quantifying the hydrogen peroxide generated. | 08-16-2012 |
20120115776 | ADIPONECTIN-CONTAINING EATING BEHAVIOR CONTROL AGENT FOR ORAL ADMINISTRATION - Disclosed is a technique that facilitates the oral ingestion of adiponectin in a large quantity and enables the expansion of the range of use applications of adiponectin. Specifically disclosed is an appetite control agent for oral administration, which comprises adiponectin as an active ingredient. Particularly, the appetite control agent comprises a transformant capable of expressing adiponectin. Also specifically disclosed is a food composition for controlling appetite, which comprises the appetite control agent. | 05-10-2012 |
20110275108 | METHOD FOR RELEASING REDUCING GLYCAN BY AMMONIUM SALT - An objective of the present invention is to provide a glycan releasing method which can be applied to construction of a system for automation of glycan analysis, and particularly a glycan releasing method capable of analyzing an O-linked glycan. The objective could be achieved as a result of finding that the pH is lowered by using an ammonium salt or ammonium ion in the absence of concentrated aqueous ammonia, not using concentrated aqueous ammonia, thus drastically avoiding an undesired side reaction such as a peeling reaction or the like. Therefore, the present invention provides a method of producing an O-linked glycan from a glycan-binding substance having the O-linked glycan, the method includes the steps of (A) bringing an ammonium salt or ammonium ion into contact with the glycan-binding substance in the absence of concentrated aqueous ammonia (for example, under the conditions of the pH of about 7 or higher and lower than about 11); (B) neutralizing the reaction solution obtained in step (A); and (C) collecting the released glycan. | 11-10-2011 |
20110243517 | UNCOUPLED MULTI-CORE FIBER - A multi-core fiber of the present invention employs the multi-core fiber mode, which corresponds to the “uncoupled” operation aspect in which individual cores are used independently for single-mode transmission, to perform space division multiplexing transmission using a multi-core fiber in which multiple single-mode cores are stored in one optical fiber. More specifically, the multi-core fiber of the present invention forms an uncoupled multi-core fiber that makes individual cores correspond to single-mode, independent transmission channels. | 10-06-2011 |
20110188855 | COUPLED SYSTEM MULTI-CORE FIBER, COUPLING MODE MULTIPLEXER AND DEMULTIPLEXER, SYSTEM FOR TRANSMISSION USING MULTI-CORE FIBER AND METHOD FOR TRANSMISSION USING MULTI-CORE FIBER - The multi-core fiber of the present invention uses a multi-core fiber configuration, compatible with the “coupled” operation mode in which coupling between cores is positively utilized, to carry out mode division multiplexing transmission via a multi-core fiber that contains multiple single-mode cores in one optical fiber. The multi-core fiber of the present invention uses a configuration in which mode multiplexing transmission is carried out using a multi-core fiber that contains multiple single-mode cores in one optical fiber, wherein multiple cores are strongly coupled intentionally to form a coupled multi-core fiber that makes the coupled modes correspond, one to one, to the transmission channels. | 08-04-2011 |
20110091956 | BIOMOLECULE-IMMOBILIZED CARRIER AND METHOD FOR IMMOBILIZING BIOMOLECULE ON CARRIER - Provided are a biomolecule-immobilized carrier obtained by immobilizing a biomolecule having a membrane-binding peptide containing a C terminal polypeptide of fucosyltransferase derived from | 04-21-2011 |
20100142677 | DYNAMIC TUMOR RADIATION TREATMENT APPARATUS AND PROGRAM - It is intended to provide a dynamic tumor radiation treatment apparatus and program for detecting the position of a tumor with high accuracy without imposing a burden on the patient, continuously detecting a tumor with high detection efficiency, and effectively irradiating only a malignant tumor with radiation to reduce the radiation exposure dose. A computer functioning by a dynamic tumor radiation treatment program includes gamma ray detecting means | 06-10-2010 |
20090142781 | Non-Liquid Phase Type Chemiluminescent Enzyme Immunoassay Method and Assay Kit - A chemiluminescent enzyme immunoassay method whereby a target substance such as a protein is assayed. This chemiluminescent enzyme immunoassay method comprises: the step of capturing an immune complex containing an enzyme-labeled antibody, which is labeled with an enzyme acting a chemiluminescent substrate, and the target substance on a support having no solution layer; the step of overlaying a support membrane containing the chemiluminescent substrate on the immune complex having been captured above; and the step of measuring the luminescence dose caused by the reaction between the enzyme-labeled antibody and the chemiluminescent substrate to thereby quantify the target substance. Since a highly sensitive chemiluminescent enzyme immunoassay is conducted by using a non-liquid phase type reaction system in the chemiluminescent enzyme immunoassay method as described above, multiple items can be assayed by using only a small amount of a specimen and, furthermore, the target substance can be assayed at a high sensitivity thereby without resorting to any troublesome procedures such as pipetting a reagent. | 06-04-2009 |
20090136563 | Method for Coating Particle with Lipid Film - A method for coating an object, i.e. a particle, with two sheets of lipid film having a space formed there between. In the method for coating a particle having a positive electrostatic-charging property with two sheets of lipid film, the particle having a positive electrostatic-charging property is brought into contact with a plurality of SUV type liposomes having a negative electrostatic-charging property to form a complex having a negative electrostatic-charging property containing the particle having a positive electrostatic-charging property and the SUV type liposomes having a negative electrostatic-charging property coupled electrostatically with the particle having a positive electrostatic-charging property, and then the complex having a negative electrostatic-charging property is treated with cation. | 05-28-2009 |
20080197281 | Electron Microscopic Method and Electron Microscope Using Same - There is provided an electron microscopic method capable of realizing a high resolution based on the principle of the phase retrieval method. An electron microscope ( | 08-21-2008 |