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National Research Council of Canada, A Crown Corporation incorporated as a Company under

National Research Council of Canada, A Crown Corporation incorporated as a Company under Patent applications
Patent application numberTitlePublished
20090162422Single-domain brain-targeting antibody fragments derived from LLAMA antibodies - A phage-displayed library of llama single heavy domain antibodies (sdAbs) was enriched for species that selectively bind to and are internalized by human cerebromicrovascular endothelial cells (HCEC). From the enriched library, two sdAbs were selected, sequenced, subcloned, and expressed as fusion proteins with c-myc-His06-25-2009