Nanopass Technologies Ltd.
|Nanopass Technologies Ltd. Patent applications|
|Patent application number||Title||Published|
|20140350514||SYSTEMS AND METHODS FOR INTRADERMAL DELIVERY OF THERAPEUTICS USING MICRONEEDLES - Methods are disclosed for delivering a substance to the skin of a human subject. The methods include, obtaining a substance, such as hormones, for example, Insulin; and delivering the substance into an intradermal space within the skin of the human subject through a plurality of microneedles. The microneedles are of a height of approximately 400 micrometers to approximately 750 micrometers.||11-27-2014|
|20130110043||Microneedle Intradermal Drug Delivery Device with Auto-Disable Functionality||05-02-2013|
|20110238038||INTRADERMAL MINI - NEEDLE INTERFACE AND ASSOCIATED DEVICES AND METHODS - An intradermal mini-needle interface has a penetration limiter providing a skin contact edge and a hollow hypodermic needle having a beveled penetrating portion protruding forward beyond the skin contact edge by no more than 3 mm. At least one skin contact surface defines a skin contact plane parallel to, or at a shallow angle to, the needle axis. The skin contact plane intersects the skin contact edge substantially at a base of the penetrating portion. Preferably, the penetration limiter is asymmetric under rotation about the needle axis.||09-29-2011|
|20110073560||Microneedle Structure And Production Method Therefor - A method for processing a wafer to form a plurality of hollow microneedles projecting from a substrate includes forming, by use of a dry etching process, a number of groups of recessed features, each including at least one slot deployed to form an open shape having an included area and at least one hole located within the included area. The internal surfaces of the holes and the slots are then coated with a protective layer. An anisotropic wet etching process is then performed in such a manner as to remove material from outside the included areas while leaving a projecting feature within each of the included areas. The protective layer is then removed to reveal the microneedles.||03-31-2011|
|20100224590||METHOD FOR PRODUCING MICRONEEDLE STRUCTURES EMPLOYING ONE-SIDED PROCESSING - A method for forming a hollow microneedle structure includes processing the front side of a wafer to form at least one microneedle projecting from a substrate and a through-bore passing through the microneedle and through a thickness of the substrate. An entire length of the through-bore is formed by a dry etching process performed from the front side of the wafer. Most preferably, upright surfaces of the microneedle structure and the through bore of the structure are formed by dry etching performed via a single mask with differing depths obtained by harnessing aspect ratio limitations of the dry etching process.||09-09-2010|
|20100106105||Microneedle Structure And Production Method Therefor - A method for processing a wafer to form a plurality of hollow microneedles projecting from a substrate includes forming, by use of a dry etching process, a number of groups of recessed features, each including at least one slot deployed to form an open shape having an included area and at least one hole located within the included area. The internal surfaces of the holes and the slots are then coated with a protective layer. An anisotropic wet etching process is then performed in such a manner as to remove material from outside the included areas while leaving a projecting feature within each of the included areas. The protective layer is then removed to reveal the microneedles.||04-29-2010|
|20090247953||MICRONEEDLE ADAPTOR FOR DOSED DRUG DELIVERY DEVICES - An adapter for achieving intradermal dosed delivery of a liquid by use of a dosed drug delivery device including a reservoir having a pierceable septum, the adapter having a connector including an attachment configuration for attachment to the dosed drug delivery device and a hollow needle deployed for piercing the septum. A liquid delivery interface, linked to the connector, includes a straight skin contact edge and one or more hollow microneedle adjacent thereto. The microneedle projects away from the skin contact edge. A flow path arrangement interconnects the needle and the at least one hollow microneedle.||10-01-2009|
|20090157094||DEVICE FOR SUPERFICIAL ABRASIVE TREATMENT OF THE SKIN||06-18-2009|
|20090069788||System And Method For Delivering Fluid Into Flexible Biological Barrier - A system and method for delivering fluid into a flexible biological barrier employs a microneedle structure wherein a final position of microneedles (||03-12-2009|
|20090054842||Enhanced penetration system and method for sliding microneedles - A microneedle device for transporting fluid through a surface of a biological barrier, the device including a fluid transport configuration, an abutment member and a displacement device. The fluid transport configuration includes a substrate having a substantially planar surface having a plurality of microneedles projecting therefrom. The abutment member has an abutment surface for abutting the biological barrier. The displacement device is configured for generating a relative lateral sliding movement between the surface of the biological barrier and the fluid transport configuration in a sliding direction of the microneedles The microneedles are arranged so that a leading microneedle defines an effective area which is effective void of another microneedle. The effective area is defined as an area marked out by translating the base area of the leading microneedle, by the height of the leading microneedle, in a direction opposite to the sliding direction.||02-26-2009|
|20090012494||INTRADERMAL DELIVERY OF BIOLOGICAL AGENTS - The present invention relates to methods for intradermally delivering one or more biologically active agents such as vaccines and therapeutic agents into the dermis layer of the skin of a subject to obtain systemic delivery or an immune response using a microneedle drug delivery device containing the agent to be delivered. The methods employ a microneedle device with a row of hollow microneedles. The microneedles penetrate the skin of the subject and assume an anchored state in which the microneedles are anchored in the skin and project laterally from the device. A pivotal motion is then performed with the device so that the skin in which the microneedles are engaged is lifted above the initial plane of the surface of the skin while the biologically active agent is delivered. The methods of the invention elicit increased humoral and/or cellular response as compared to conventional vaccine delivery routes, facilitating dose sparing.||01-08-2009|
|20090011158||MICRONEEDLE STRUCTURES AND CORRESPONDING PRODUCTION METHODS EMPLOYING A BACKSIDE WET ETCH - A method for forming a hollow microneedle structure includes processing the front side of a wafer to form at least one microneedle projecting from a substrate with a first part of a through-bore, formed by a dry etching process, passing through the microneedle and through a part of a thickness of the substrate. The backside of the wafer is also processed to form a second part of the through-bore by a wet etching process.||01-08-2009|
Patent applications by Nanopass Technologies Ltd.