MUSCULOSKELETAL TRANSPLANT FOUNDATION Patent applications |
Patent application number | Title | Published |
20150037436 | ACELLULAR SOFT TISSUE-DERIVED MATRICES AND METHODS FOR PREPARING SAME - An acellular soft tissue-derived matrix includes a collagenous tissue that has been delipidated and decellularized. Adipose tissue is among the soft tissues suitable for manufacturing an acellular soft tissue-derived matrix. Exogenous tissuegenic cells and other biologically-active factors may be added to the acellular matrix. The acellular matrix may be provided as particles, a slurry, a paste, a gel, or in some other form. The acellular matrix may be provided as a three-dimensional scaffold that has been reconstituted from particles of the three-dimensional tissue. The three-dimensional scaffold may have the shape of an anatomical feature and serve as a template for tissue repair or replacement. A method of making an acellular soft tissue-derived matrix includes steps of removing lipid from the soft tissue by solvent extraction and chemical decellularization of the soft tissue. | 02-05-2015 |
20140276957 | SOFT TISSUE REPAIR ALLOGRAFTS AND METHODS FOR PREPARING SAME - Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. One allograft is made from decellularized dermal tissue and constitutes a collagen matrix having substantially uniform density and porosity. Another allograft is a hybrid bilayer tissue form that is made from decellularized dermal and adipose tissues. Methods for making both allografts are also disclosed. | 09-18-2014 |
20140058527 | CARTILAGE REPAIR MIXTURE CONTAINING ALLOGRAFT CHONDROCYTES - The invention is directed toward a sterile cartilage defect implant material comprising milled lyophilized allograft cartilage pieces ranging from 0.01 mm to 1.0 mm in size in a bioabsorbable carrier taken from a group consisting of sodium hyaluronate, hyaluronic acid and its derivatives, gelatin, collagen, chitosan, alginate, buffered PBS, Dextran or mixed polymers with allograft chondrocytes added in an amount ranging from 2.5×10 | 02-27-2014 |
20140039628 | ALLOGRAFT INTERVERTEBRAL IMPLANT AND METHOD OF MANUFACTURING THE SAME - The present invention is directed to an allograft intervertebral implant sized and configured for insertion between adjacent vertebral bodies in a spinal fusion surgery. The implant is preferably manufactured from two or more pieces of allograft bone joined together by a joint, more preferably a dovetail joint. The dovetail joint being sized and configured to substantially follow the exterior shape or surface of the intervertebral implant. | 02-06-2014 |
20130096680 | Instrumentation for repair of meniscus tissue - The invention is directed toward an instrumentation kit used to replace a damaged human knee joint meniscus with an allograft meniscus implant. The kit includes a workstation having a base and upright end sections with a clamping assembly is mounted on the end sections and a movable cutting guide mounted to a side wall of each end section. The tibia is then drilled with a drill to a desired depth and length and a groove is formed in the tibia with an osteotome so that the width is the same as the width of the bone base of the meniscus implant which has been trimmed in the workstation. | 04-18-2013 |
20130030534 | ALLOGRAFT INTERVERTEBRAL IMPLANT AND METHOD OF MANUFACTURING THE SAME - The present invention is directed to an allograft intervertebral implant sized and configured for insertion between adjacent vertebral bodies in a spinal fusion surgery. The implant is preferably manufactured from two or more pieces of allograft bone joined together by a joint, more preferably a dovetail joint. The dovetail joint being sized and configured to substantially follow the exterior shape or surface of the intervertebral implant. | 01-31-2013 |
20130011446 | CERAMIC COMPOSITION FOR FILLING BONE DEFECTS - The invention is directed toward a sterile formable implant composition for application to a bone defect site comprising bioactive glass particles in an aqueous carrier solution, the bioactive glass particles being added to a viscous carrier at a concentration ranging from about 68% to about 76% (w/w), the carrier comprising a mixture of glycerol and polyethylene glycol ranging from 24% to 32% (w/w) with the ratio of glycerol to polyethylene glycol ranging from about 45:55 to about 65:35. | 01-10-2013 |
20120297550 | PROCESS FOR STERILIZING ACELLULAR SOFT TISSUE WITH IRRADIATION - The present invention relates to a process for preparing skin removed from a human donor, removal of cellular components and sterilizing the decellularized skin. The process comprises the following steps: | 11-29-2012 |
20110070284 | BIOLOGIC MATRICES COMPRISING ANTI-INFECTIVE METHODS AND COMPOSITIONS RELATED THERETO - Described herein are methods and compositions related to biologic matrices comprising at least one anti-infective. In certain embodiments, the invention relates to a biologic matrix comprising a slowed release anti-infective agent. In a particular embodiment, the invention relates to an acellular dermal matrix comprising a slowed release antiinfective agent, wherein the anti-infective agent is triclosan. In further embodiments, the the biologic matrix is suitable for use in surgical procedures, such as, for example, for the replacement of damaged or inadequate integumental tissue or for the repair, reinforcement or supplemental support of soft tissue defects. | 03-24-2011 |
20100323440 | PROCESS FOR STERILIZING ACELLULAR SOFT TISSUE UNDER PRESSURE - The present invention relates to a process for preparing skin removed from a human donor, removal of cellular components and sterilizing the decellularized skin. The process comprises the following steps:
| 12-23-2010 |
20100304487 | SOFT TISSUE PROCESSING - The present invention is a process for preparing soft tissue such as tendons, ligaments, cartilage, fascia, dermis, human valves and human veins for implant in a human and removes cellular components and forms an decellular matrix having as major components collagens and elastins while sterilizing the tissue. The process comprises the following steps: | 12-02-2010 |
20100296969 | PROCESS FOR STERILIZING ACELLULAR SOFT TISSUE UNDER VACUUM - The present invention is a process for preparing skin removed from a human donor, removal of cellular components and sterilizing the decellularized skin. The process comprises the following steps:
| 11-25-2010 |
20100291532 | PROCESS FOR STERILIZING ACELLULAR SOFT TISSUE WITH IRRADIATION - The present invention relates to a process for preparing skin removed from a human donor, removal of cellular components and sterilizing the decellularized skin. The process comprises the following steps:
| 11-18-2010 |