MONELL CHEMICAL SENSES CENTER Patent applications |
Patent application number | Title | Published |
20140093978 | Human Salty Taste Receptor And Methods Of Modulating Salty Taste Perception - Methods for identifying modulators of the epithelial sodium ion channel and for identifying modulators of salty taste perception are described. Also featured are isolated human salty taste receptors, artificial lipid bilayers comprising an epithelial sodium ion channels, and kits for practicing the claimed methods. | 04-03-2014 |
20130280371 | Compositions and Methods for Providing or Modulating Sweet Taste or Methods of Screening Therefor - The present invention provides methods for identifying a molecule that provides or enhances a sweet taste in the mouth and compositions containing such molecules. The methods involve determining the effect of a variety of known or new compounds on expression or functional activity of a glucose-transporter protein of the activity of an ATP-gated K+ channel (K | 10-24-2013 |
20130209625 | METHODS AND COMPOSITIONS FOR STIMULATING A FELIDAE T1R RECEPTOR - Provided herein are methods for stimulating the T1R1/T1R3 receptor comprising contacting the receptor with pyrophosphate and one or more amino acids. Also provided, is a Felidae food product comprising pyrophosphate and one or more amino acids. Methods for determining the pyrophosphate-augmented activity of a test compound on the T1R1/T1R3 receptor are also described, as well as methods for adjusting the food formulation for Felidae. | 08-15-2013 |
20130078351 | COMPOUNDS AND METHODS FOR ENHANCING SALTY TASTE - The present invention is directed to compounds that increase the saltiness intensity of sodium chloride in human taste. Compositions and foods comprising these compounds are also described. | 03-28-2013 |
20120184828 | MRI COMPATIBLE AND AIR-ACTUATED OLFACTOMETER - An olfactometer is disclosed. Such an olfactometer may include a control unit, an odor box, and a nose piece in communication with the odor box. The control unit may include a reservoir, and a compressor for supplying pressurized air to the reservoir. The odor box may include at least one compressed air actuated valve, and at least one odor canister in communication with the valve. A compressed air flow and a breathable air flow are both released from the reservoir and directed to the valve. The compressed air flow actuates the valve to thereby direct the breathable air to the odor canister to odorize the breathable air. The odorized breathable air is then directed to the nose piece. | 07-19-2012 |
20120184459 | Taste Receptors Of The T1R Family From Domestic Cat - The present invention relates to the discovery of several genes of the domestic cat ( | 07-19-2012 |
20120183975 | Taste Receptors Of The T1R Family From Domestic Dog - The present invention relates to the discovery of several genes of the domestic dog ( | 07-19-2012 |
20110269235 | METHODS FOR CULTURING MAMMALIAN TASTE CELLS - The invention provides methods of culturing mammalian taste cells, including taste receptor cells. Cells are maintained for a duration of up to three months and longer while maintaining molecular and functional characteristics of mature taste cells. The cells are cultured on coated cell culture vessels and, from first replacement of medium onwards, the medium is replaced in intervals of at least 5 days. The invention further provides isolation and culturing methods of taste cells wherein the time that the cells are exposed to isolation solution and proteolytic enzymes is minimized and the cells are cultured in coated culture vessels with the medium replaced in intervals of at least 5 days from first replacement onwards. The invention further provides cultured taste cells, transfection and assay methods, and taste cell assay buffers with an osmolarity of about 300-320 and pH of about 7.0-7.3. | 11-03-2011 |
20110236313 | HUMAN SALTY TASTE RECEPTOR AND METHODS OF MODULATING SALTY TASTE PERCEPTION - Methods for identifying modulators of the epithelial sodium ion channel and for identifying modulators of salty taste perception are described. Also featured are isolated human salty taste receptors, artificial lipid bilayers comprising an epithelial sodium ion channels, and kits for practicing the claimed methods. | 09-29-2011 |
20100319075 | STG Promoter And Its Use As A Marker For Taste And Oocyte Cells - The present invention relates to a polynucleotide vector comprising the Simian taste-bud specific gene (STG) promoter operatively linked to a reporter gene. In preferred embodiments, the STG promoter is the murine ortholog of the STG promoter. In other preferred embodiments, the STG promoter is the human ortholog of the STG promoter. In some preferred embodiments, the reporter gene is green fluorescent protein (GFP). Additionally provided are vectors comprising the STG promoter operatively linked to a cre-recombinase gene. | 12-16-2010 |
20100254927 | OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS - Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants. Methods of making deodorant compositions are also provided wherein a cross-adapting agent, alone or in combination with other such agents, are included in an amount effective to reduce perception of malodor. | 10-07-2010 |
20090233379 | Taste Receptors Of The T1R Family From Domestic Dog - The present invention relates to the discovery of several genes of the domestic dog ( | 09-17-2009 |
20090205061 | Taste Receptors Of The T1R Family From Domestic Cat - The present invention relates to the discovery of several genes of the domestic cat ( | 08-13-2009 |
20080307536 | Voltage-Gated, Ph-Sensitive Anion Channel And Its Novel Splice Variant Involved In Taste Sensation - The invention provides a novel splice-variant of the ClC-4 protein, termed ClC-4A. ClC-4A is expressed in taste bud cells and is involved in sour taste perception. The invention provides ClC-4A polynucleotides and ClC-4A polypeptides, vectors, host cells and ClC-4A specific antibodies as well as designing high potency taste stimuli, determining taste preferences in animals, developing breed-specific foods, and modifying the taste of foods and medications. | 12-11-2008 |
20080274912 | Single Walled Carbon Nanotubes Functionally Adsorbed to Biopolymers for Use as Chemical Sensors - Chemical field effect sensors comprising nanotube field effect devices having biopolymers such as single stranded DNA functionally adsorbed to the nanotubes are provided. Also included are arrays comprising the sensors and methods of using the devices to detect volatile compounds. | 11-06-2008 |