| Mitsubishi Tanabe Pharma Corporation Patent applications |
| Patent application number | Title | Published |
|---|
| 20120135947 | OIL-IN-WATER EMULSION COMPOSITION CONTAINING DIFLUPREDNATE AND TOBRAMYCIN - The present invention provides an oil-in-water emulsion composition for topical administration, containing (a) tobramycin, (b) difluprednate, (c) water, (d) oil and (e) an emulsifier. Moreover, it provides a method for stabilizing tobramycin, which includes mixing (a) tobramycin, (b) difluprednate, (c) water, (d) oil and (e) an emulsifier to form an oil-in-water emulsion. The present invention can provide an oil-in-water emulsion composition containing tobramycin, which can maintain tobramycin content stably even when a non-ionic surfactant is added. | 05-31-2012 |
| 20120135534 | ADSORPTION TEST METHOD OF SPHERICAL CARBON ADSORBENT - The present invention relates to an adsorption test method of a spherical carbon adsorbent, particularly Kremezin, which includes evaluating a test solution containing one or more kinds of particular uremic toxins or related compounds for the adsorbability, namely, adsorption titer, adsorption speed and/or adsorption selectivity, of the spherical carbon adsorbent. | 05-31-2012 |
| 20120129812 | NOVEL THYROID HORMONE BETA RECEPTOR AGONIST - Provided is a heterocyclic derivative showing a thyroid hormone β receptor agonist action, which is effective for the prophylaxis or treatment of the diseases relating to the action. A compound represented by the formula [I]: | 05-24-2012 |
| 20120095216 | 3-[1,4]OXAZEPANE-4-PYRIMIDONE DERIVATIVES - A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: | 04-19-2012 |
| 20120064570 | NOVEL CELL PENETRATING PEPTIDE - According to the present invention, it is possible to provide a novel cell penetrating peptide that transports proteins into cells and/or into nuclei at higher frequency than conventional cell penetrating peptides, and a pharmaceutical containing the peptide. | 03-15-2012 |
| 20110294786 | SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES - A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 12-01-2011 |
| 20110282058 | SALT OF PROLINE DERIVATIVE, SOLVATE THEREOF, AND PRODUCTION METHOD THEREOF - The present invention provides 3-{(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin- | 11-17-2011 |
| 20110263571 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE - Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I) | 10-27-2011 |
| 20110257392 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF - The present invention relates to a production method of an optically active morpholine compound represented by the formula 10, which includes the following steps: | 10-20-2011 |
| 20110251385 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF - The present invention relates to a production method of an optically active morpholine compound represented by the formula 10, which includes the following steps: | 10-13-2011 |
| 20110224220 | SUBSTITUTED TRICYCLIC DERIVATIVES - Compounds of formula (I): | 09-15-2011 |
| 20110144138 | SUBSTITUTED PYRIMIDO ISOQUINOLINE DERIVATIVES - Pyrimido isoquinoline derivatives represented by formula (I): | 06-16-2011 |
| 20110144133 | SUBSTITUTED PYRIMIDONE DERIVATIVES - Pyrimidone derivatives of formula (I) | 06-16-2011 |
| 20110144132 | SUBSTITUTED PYRIMIDIN-4-ONE DERIVATIVES - A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 06-16-2011 |
| 20110144114 | SUBSTITUTED TRIAZINONE DERIVATIVES - Triazinone derivatives represented by formula (I) | 06-16-2011 |
| 20110144092 | SUBSTITUTED ALKYL PYRIMIDIN-4-ONE DERIVATIVES - A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 06-16-2011 |
| 20110136828 | SUBSTITUTED N-OXIDE PYRAZINE DERIVATIVES - N-oxide pyrazine derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 06-09-2011 |
| 20110130419 | NOVEL SALT OF ISOQUINOLINE COMPOUND AND CRYSTAL THEREOF - The invention provides a salt of (R)-3-[2-(2-hydroxymethylpyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one and a crystal thereof. (R)-3-[2-(2-Hydroxymethylpyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one monophosphate is a compound which is chemically stable, has high solubility, and shows less weight change due to humidity as compared to a free form and monohydrochloride dihydrate, and is superior as a bulk drug for pharmaceutical products. | 06-02-2011 |
| 20110068037 | PLASTIC CONTAINER COMPRISING CYCLIC POLYOLEFIN LAYER - The present invention provides and a plastic container and multilayered films, which comprises a heat-sealable seal layer, a cyclic polyolefin layer, and an outermost layer, wherein the seal layer comprises polypropylene, the cyclic polyolefin layer comprises a cyclic polyolefin polymer or a cyclic polyolefin copolymer, and the outermost layer comprises a layer containing polypropylene, and which further comprises a resin composition layer comprises a blended product of a propylene polymer and a styrene elastomer. The plastic container of the present invention can suppresses a reduction in the medicament content of a liquid-state medicament and is excellent in terms of shock resistance, handling ability during the filling of the container with the medicament, and the moldability and transparency of the container. | 03-24-2011 |
| 20110039835 | SUBSTITUTED ARYLAMIDE DIAZEPINOPYRIMIDONE DERIVATIVES - The disclosure relates to a series pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 02-17-2011 |
| 20110034440 | HOMOCYSTEINE SYNTHASE INHIBITOR - The invention provides a homocysteine synthase inhibitor useful for the prophylaxis or treatment of diseases involving homocysteine synthase. The homocysteine synthase inhibitor is a compound of the formula (I) | 02-10-2011 |
| 20110034435 | PYRIMIDINE, PYRIDINE AND TRIAZINE DERIVATIVES AS MAXI-K CHANNEL OPENERS - A compound of formula (A); wherein ring A is an aromatic ring or a heteroaromatic ring; R | 02-10-2011 |
| 20110021773 | 6-PYRIMIDINYL-PYRIMID-4-ONE DERIVATIVE - A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: | 01-27-2011 |
| 20110015187 | SUBSTITUTED HETEROARYLAMIDE DIAZEPINOPYRIMIDONE DERIVATIVES - The disclosure relates to a series pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 01-20-2011 |
| 20110015177 | SUBSTITUTED ARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES - The disclosure relates to a series pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 01-20-2011 |
| 20110015176 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES - The disclosure relates to a series pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 01-20-2011 |
| 20100320215 | PLASTIC CONTAINER COMPRISING CYCLIC POLYOLEFIN LAYER - The present invention provides and a plastic container and multilayered films, which comprises a heat-sealable seal layer, a cyclic polyolefin layer, and an outermost layer, wherein the seal layer comprises polypropylene, the cyclic polyolefin layer comprises a cyclic polyolefin polymer or a cyclic polyolefin copolymer, and the outermost layer comprises a layer containing polypropylene, and which further comprises a resin composition layer comprises a blended product of a propylene polymer and a styrene elastomer. The plastic container of the present invention can suppresses a reduction in the medicament content of a liquid-state medicament and is excellent in terms of shock resistance, handling ability during the filling of the container with the medicament, and the moldability and transparency of the container. | 12-23-2010 |
| 20100305159 | CRYSTALLINE FORM OF PIPERIDINE COMPOUND - The present invention is to provide a crystalline form of (2R,4S)-1-{N-(3,5-bistrifluoromethylbenzyl)-N-methyl}aminocarbonyl-2-(4-fluoro-2-methylphenyl)-4-(2-hydroxyethylaminocarbonyloxy)piperidine or a solvate thereof. | 12-02-2010 |
| 20100305139 | METHOD OF TREATING ABNORMAL LIPID METABOLISM - The present invention provides a pharmaceutical agent for the treatment and/or prophylaxis of abnormal blood glucose and lipid metabolism associated with eating, for which a sufficient treatment method or a therapeutic drug has not been found. | 12-02-2010 |
| 20100286127 | ANTITUMOR AGENT - The present invention relates to a novel antitumor agent containing a compound that inhibits binding between acetylated histone and a bromodomain-containing protein, preferably a thienotriazolodiazepine compound represented by the following formula (I) | 11-11-2010 |
| 20100228026 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF - The invention provides a sulfonyl malonamide derivative, or a pharmacologically acceptable salt thereof or a solvate thereof, that has therapeutic and/or preventive effect(s) on various diseases due to its agonist action at AT | 09-09-2010 |
| 20100226974 | ANTIBODY RECOGNIZING ANTIGEN - The invention provides antibodies against a non-muscular myosin heavy chain type A or a mutant thereof, and F(ab′) | 09-09-2010 |
| 20100184221 | METHOD FOR ISOLATION OF CELL, SERUM-FREE CULTURE MEDIUM FOR CELL, AND METHOD FOR CULTURE OF CELL - The present invention provides a method for isolating cells, in particular, stem cells, which method comprises the steps of: dissociating cells from a tissue of animal origin; seeding and incubating the cells in a culture vessel with no surface treatment; and selecting cells adhered to the vessel. | 07-22-2010 |
| 20100179157 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION - The present invention provides a novel therapeutic drug for cerebral infarction, which contains a piperazine compound as an active ingredient. | 07-15-2010 |
| 20100152261 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND - A nitrogen-containing heterocyclic derivative represented by the following general formula (I), or a hydrate or solvate thereof, which has a selective antagonistic action on the muscarinic M | 06-17-2010 |
| 20100113775 | 2-SUBSTITUTED-6-HETEROCYCLIC PYRIMIDONE DERIVATIVES AS TAU PROTEIN KINASE 1 INHIBITORS - A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein each R | 05-06-2010 |
| 20100087461 | ARYLAMIDE PYRIMIDONE COMPOUNDS - The present invention discloses a series of pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 04-08-2010 |
| 20100087460 | ARYLAMIDE PYRIMIDONE DERIVATIVES - The present invention discloses a series of pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 04-08-2010 |
| 20100087449 | HETEROARYLAMIDE PYRIMIDONE COMPOUNDS - The present invention discloses a series of pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 04-08-2010 |
| 20100081677 | HETEROARYLAMIDE PYRIMIDONE DERIVATIVES - The present invention discloses a series of pyrimidone derivatives represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 04-01-2010 |
| 20100063055 | CONDENSED TETRAHYDROQUINOLINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES - The problem of the present invention is to provide a compound having a GR selective binding activity, which shows less action on other nuclear receptors such as progesterone receptor (PR), mineralocorticoid receptor (MR) and the like. The present invention provides a condensed tetrahydroquinoline compound represented by the following formula (I) | 03-11-2010 |
| 20100048487 | NOVEL CELL PENETRATING PEPTIDE - According to the present invention, it is possible to provide a novel cell penetrating peptide that transports proteins into cells and/or into nuclei at higher frequency than conventional cell penetrating peptides, and a pharmaceutical containing the peptide. | 02-25-2010 |
| 20100041643 | THIENOTRIAZOLODIAZEPINE COMPOUND AND MEDICINAL USE THEREOF - [Solving means] A thienotriazolodiazepine compound of the following formula (I) | 02-18-2010 |
| 20090325207 | NOVEL PHOSPHODIESTERASE AND GENE THEREOF - The present invention is to provide a novel phosphodiesterase and a gene thereof, specifically, Type 11 phosphodiesterase (PDE11) and a gene thereof, more specifically, a phosphodiesterase selected from (A) a protein having an amino acid sequenced shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39, and (B) a protein having an amino acid sequence shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: in which one or several amino acids are deleted, substituted or added, and having an activity of hydrolyzing a cyclic nucleotide, and a gene thereof, and a method of characterizing, identifying and selecting a phosphodiesterase inhibitor by using the same. | 12-31-2009 |
| 20090306088 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES - A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof are disclosed and claimed. | 12-10-2009 |
| 20090292125 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES - The present invention is to provide a process for preparing optically active tetrahydroquinoline derivatives which can be used for the treatment and/or prevention of diseases such as arteriosclerotic diseases, dyslipidemia and the like, and a process for preparing synthetic intermediates thereof. | 11-26-2009 |
| 20090281121 | SUBSTITUTED 8-PIPERIDINYL-2-PYRIDINYL-PYRIMIDO[1,2-a] PYRIMIDIN-6-ONE AND 8-PIPERIDINYL-2-PYRIMIDINYL-PYRIMIDO[1,2-a] PYRIMIDIN-6-ONE DERIVATIVES - The invention relates to a pyrimidone derivative represented by formula (I) or a salt thereof: | 11-12-2009 |
| 20090281095 | THIOMORPHOLINE COMPOUND AND PROCESS FOR PREPARING THE SAME - The present invention discloses a thiomorpholine compound represented by the formula [I]: | 11-12-2009 |
| 20090156804 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF - The present invention relates to a production method of an optically active morpholine compound represented by the formula 10, which includes the following steps: | 06-18-2009 |
| 20090137530 | Amine Compound and Use Thereof for Medical Purposes - A novel amine compound represented by the following formula (I), which is superior in immunosuppressive action, rejection suppressive action and the like, and shows reduced side effects such as bradycardia and the like, or a pharmaceutically acceptable acid addition salt thereof, or hydrates thereof, or solvate, as well as a pharmaceutical composition containing this compound and a pharmaceutically acceptable carrier. | 05-28-2009 |
| 20090110655 | PROPHYLACTIC AND/OR THERAPEUTIC DRUG FOR NONALCOHOLIC STEATOHEPATITIS - The present invention provides a method for the treatment of nonalcoholic steatohepatitis with a pharmaceutically acceptable anion exchange resin such as, for example, colestimide. | 04-30-2009 |
| 20090088449 | 4-ACYLAMINOPYRIDINE DERIVATIVE MEDIATED NEUROGENESIS - The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The invention includes methods based on use of a 4-acylaminopyridine derivative to stimulate or activate the formation of new nerve cells. | 04-02-2009 |
| 20090088442 | PROPHYLACTIC/THERAPEUTIC AGENT FOR ABNORMALITIES OF SUGAR/LIPID METABOLISM - The present invention provides a pharmaceutical agent for the treatment and/or prophylaxis of abnormal blood glucose and lipid metabolism associated with eating, for which a sufficient treatment method or a therapeutic drug has not been found. | 04-02-2009 |
| 20090082311 | 2-Aminobutanol Compound and Use Thereof for Medical Purposes - The present invention provides a novel compound having few side effects such as bradycardia and the like and having superior peripheral blood lymphocyte-decreasing effect. | 03-26-2009 |
| 20090082256 | CONCOMITANT PHARMACEUTICAL AGENTS AND USE THEREOF - A concomitant agent to be used simultaneously or separately, comprising a combination of (a) 3-{(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl}thiazolidine, a salt of the compound with an organic or inorganic and mono- or di-basic acid or a solvate thereof, and | 03-26-2009 |
| 20090076276 | ISOQUINOLINE COMPOUND AND PHARMACEUTICAL USE THEREOF - The present invention relates to an isoquinoline compound represented by the following formula (I), an optically active form thereof, a pharmaceutically acceptable salt thereof, a water adduct thereof, a hydrate thereof and a solvate thereof, as well as an agent for the prophylaxis and/or treatment of a disease caused by hyperreactivity of poly(ADP-ribose)polymerase, containing the compound, and a poly(ADP-ribose)polymerase inhibitor containing the compound. In addition, this compound is useful as an agent for the prophylaxis and/or treatment of cerebral infarction, particularly as an agent for the prophylaxis and/or treatment of acute cerebral infarction. Furthermore, this compound is useful as a prophylactic and/or therapeutic agent that improves neurological symptoms associated with cerebral infarction, particularly acute cerebral infarction. | 03-19-2009 |
| 20090053300 | MONOCLONAL ANTIBODY, GENE ENCODING THE ANTIBODY, HYBRIDOMA, PHARMACEUTICAL COMPOSITION, AND DIAGNOSTIC REAGENT - Disclosed is a monoclonal antibody which has a heavy chain variable region containing amino acid sequences depicted in SEQ ID NOs:74, 76 and 78 and a light chain variable region containing amino acid sequences depicted in SEQ ID NOs:80, 82 and 84. The monoclonal antibody can be used as a cancer therapeutic agent which acts selectively on a cancer tissue of non-small lung cancer, pancreatic cancer, gastric cancer or the like. | 02-26-2009 |
| 20090036427 | SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES - A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: | 02-05-2009 |
| 20090029994 | Trisubstituted amine compound - The present invention relates to a compound of the general formula (1): | 01-29-2009 |
| 20090023729 | Trisubstituted amine compound - The present invention relates to a compound of the general formula (1): | 01-22-2009 |
