MITSUBISHI KAGAKU IATRON, INC. Patent applications |
Patent application number | Title | Published |
20130011856 | CARTRIDGE FOR AUTOMATIC MEASUREMENT AND MEASURING DEVICE USING THE SAME - An object of the present invention is to provide a cartridge for automatic measurement used in an automatic measuring device, capable of automatically performing measurement including heat treatment of a sample, and a measuring device using the cartridge. | 01-10-2013 |
20100304503 | PROCESS FOR PRODUCING POLYMER PARTICLES - A process for producing polymer particles having an antigen or an antibody introduced into the surface thereof, by carrying out miniemulsion polymerization using a monomer, a radical polymerization initiator, an emulsifier, and a hydrophobe in the presence of the antigen or antibody to thereby produce the polymer particles, is disclosed. According to the process, it is possible to provide a reagent for immunological analysis having an excellent detection sensitivity and capable of avoiding a nonspecific reaction which occurs in conventional methods. | 12-02-2010 |
20100197042 | REAGENT AND METHOD FOR IMMUNOLOGICAL ANALYSIS - A reagent for immunological analysis, comprising a suspension of latex particles having an antigen or an antibody specific for a substance to be analyzed introduced into the surface of the latex particles, produced by polymerizing a monomer in the presence of the antigen or antibody to thereby synthesize the latex particles; and a method for immunological analysis, comprising the step of bringing, in a liquid, (1) a sample suspected of containing a substance to be analyzed, into contact with (2) latex particles having an antigen or an antibody specific for the substance introduced into the surface of the latex particles, produced by polymerizing a monomer in the presence of the antigen or antibody to thereby synthesize the latex particles; are disclosed. The reagent and the method have an excellent detection sensitivity, and can avoid a nonspecific reaction which occurs in conventional methods. | 08-05-2010 |
20090220990 | METHOD AND KIT FOR DETECTING CONDITION IN PATIENT WITH DISTURBANCE OF CONSCIOUSNESS - A method for detecting a condition in a patient with disturbance of consciousness, by analyzing an amount and/or activity of a von Willebrand factor-cleaving protease, and a kit for detecting a condition in a patient with disturbance of consciousness, comprising an antibody or a fragment thereof which specifically binds to a von Willebrand factor-cleaving protease, or a von Willebrand factor or a fragment thereof, are disclosed. Examples of the detection of a condition include a detection of cerebrovascular disease, a detection of arteriosclerotic vascular disease, and a detection or prediction of severity. | 09-03-2009 |
20090215198 | Immunological Latex Turbidimetry Method and Reagent Therefor - An immunological latex turbidimetry method for analyzing an antigen or antibody in a sample, comprising steps of:
| 08-27-2009 |
20090075298 | METHOD OF ANALYZING ENZYME - A method of analyzing an enzyme, comprising (1) bringing a sample suspected of containing an enzyme to be analyzed into contact with an enzyme substrate which is immobilized on an insoluble carrier and can be cleaved by the enzyme, in a liquid, (2) separating the insoluble carrier from the liquid, and (3) analyzing a substrate or a fragment thereof which remains on the insoluble carrier and/or a fragment of the substrate which is released from the insoluble carrier into the liquid; and a kit for analyzing an enzyme, comprising at least an enzyme substrate which is immobilized on an insoluble carrier and can be cleaved by the enzyme, are disclosed. | 03-19-2009 |
20090068682 | IMMUNOLOGICAL ASSAY FOR PLASMIN-DIGESTED PRODUCTS OF STABILIZED FIBRIN - A method of immunologically analyzing plasmin-digested products of stabilized fibrin, characterized by using a combination of a monoclonal antibody (a) which does not react with stabilized fibrin, fibrinogen, and plasmin-digested products of fibrinogen, but reacts with a neoantigen which is newly exposed in a D domain by digesting stabilized fibrin with plasmin, and a monoclonal antibody (b) which recognizes a site different from that recognized by the monoclonal antibody (a), and specifically reacts with plasmin-digested products of stabilized fibrin, wherein one of the monoclonal antibodies (a) and (b) is carried on a magnetic particle, and the other is labeled with an enzyme, and a chemiluminescent substrate is used as a substrate for the enzyme, is disclosed. | 03-12-2009 |
20090004750 | Method of Diagnosing Cerebral Infarction - A method of diagnosing cerebral infarction comprising the step of measuring the concentration of nick β2 glycoprotein I in a body fluid sample; and a method of diagnosing cerebral infarction comprising the steps of measuring the nicked β2 glycoprotein I concentration (N) and the total β2 glycoprotein I concentration (T) in a body fluid sample, calculating the ratio (N/T) of the nicked β2 glycoprotein I concentration (N) to the total β2 glycoprotein I concentration (T), and using the ratio as an indicator, are disclosed. | 01-01-2009 |
20090004673 | Method for Determining Condition of Disseminated Intravascular Coagulation - A method for determining a condition of disseminated intravascular coagulation (DIC), by analyzing the amount and/or enzyme activity of a von Willebrand factor (vWF)-cleaving protease (ADAMTS13) (preferably also the amount of vWF) in a patient suffering from DIC, and a kit for determining a condition of DIC, comprising an antibody or a fragment thereof which specifically binds to ADAMTS13, are disclosed. According to the present invention, a differential diagnosis of patients with thrombotic thrombocytopenic purpura (TTP) can be carried out from among patients with DIC, which could not be distinguished on the basis of only clinical findings or known markers. | 01-01-2009 |
20080318323 | Apparatus for Multiple Automatic Analysis of Biosamples, Method for Autoanalysis, and Reaction Cuvette - A biosample multiple autoanalyzer characterized by including: (1) a sample supply unit having a plurality of biosamples; (2) a first measuring unit fitted with a first optical measuring means capable of detachably holding, in a mutually independent fashion, a plurality of reaction cuvettes independent from each other; (3) a sample transport means capable of transporting the biosamples from the sample supply unit to the reaction cuvettes on the first measuring unit; (4) a second measuring unit fitted with a second optical measuring means capable of detachably holding, in a mutually independent fashion, a plurality of reaction cuvettes independent from each other; (5) a cuvette transfer means capable of transferring the reaction cuvettes on the first measuring unit to the second measuring unit; (6) a reagent supply unit having reagents for use in measuring by the first measuring unit and measuring by the second measuring unit; and (7) a reagent transport means capable of transporting reaction reagents, in a mutually independent fashion, from the reagent supply unit to the reaction cuvettes on the first measuring unit and/or second measuring unit, and characterized by being arranged such that the reaction cuvettes on the second measuring unit are dispensed with the biosamples on the first measuring unit, subsequently transferred from the first measuring unit to the second measuring unit by the cuvette transfer means, and retained thereon, and such that different measurements are carried out by the first measuring unit and the second measuring unit. | 12-25-2008 |