| MICROBIA, INC. Patent applications |
| Patent application number | Title | Published |
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| 20110021843 | PRODUCTION OF CAROTENOIDS IN OLEAGINOUS YEAST AND FUNGI - The present invention provides systems for producing engineered oleaginous yeast or fungi that express carotenoids | 01-27-2011 |
| 20110014669 | Production of 1,4 Butanediol in a Microorganism - A biological method for the conversion of L-glutamate to 1,4-butanediol that involves a decarboxylation step and avoids production of 4-hydroxybutyrate as an intermediate is described. The method includes: (a) conversion of L-glutamate to L-glutamate 5-phosphate; (b) conversion of L-glutamate 5-phosphate to L-glutamate 5-semialdehyde; (c) conversion of L-glutamate 5-semialdehyde to 5-hydroxy-L-norvaline; (d) conversion of 5-hydroxy-L-norvaline to 5-hydroxy-2-oxopentanoate; (e) conversion of 5-hydroxy-2-oxopentanoate to 4-hydroxybutanal; and (f) the conversion of 4-hydroxybutanal to 1,4-butanediol. | 01-20-2011 |
| 20090253634 | Methods and Compositions for the Treatment of Gastrointestinal Disorders - The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastnoesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), and disorders and conditions associated with constipation, e.g. constipation associated with use of opiate pain killers, post-surgical constipation (post-operative ileus), and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor. | 10-08-2009 |
| 20090186834 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS - Various azetidinone, pyrrolidine, imidazolidine, and oxazolidine derivatives are described, as are pharmaceutical compositions containing these compounds and methods of treatment of diseases using these compounds. Other embodiments are also described. | 07-23-2009 |
| 20090131395 | BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS - The invention relates to a chemical genus of 4-biphenyl-1-phenylazetidin-2-ones useful in the treatment of hypercholesterolemia and other disorders. The compounds have the general formula I: | 05-21-2009 |
| 20090099355 | Processes for Production of 4-(Biphenylyl)Azetidin-2-One Phosphonic Acids - The present invention relates to processes for the production of 4-(biphenylyl)azetidin-2-one phosphonic acid derivatives of formula | 04-16-2009 |
| 20090054319 | Methods and Compositions for the Treatment of Hypertension and Gastrointestinal Disorders - The use of guanylin potentiating agents for treating various disorders, including hypertension as well as IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, chronic intestinal pseudo-obstruction, colonic pseudo-obstruction, Crohn's disease, duodenogastric reflux, dyspepsia, functional dyspepsia, nonulcer dyspepsia, a functional gastrointestinal disorder, functional heartburn, gastroesophageal reflux disease (GERD), gastroparesis, inflammatory bowel disease, irritable bowel syndrome, post-operative ileus, ulcerative colitis, chronic constipation, and disorders and conditions associated with constipation is described. | 02-26-2009 |
| 20090005321 | Phenylazetidinone Derivatives - Various azetidinone derivatives are described, as are pharmaceutical compositions containing these compounds and methods of treatment of diseases using these compounds. Other embodiments are also described. | 01-01-2009 |
| 20080287663 | Process For Production Of 4-Biphenylyazetidin-2-Ones - The present invention relates to processes for the production of 4-biphenylylazetidin-2-one derivatives of formula | 11-20-2008 |
| 20080200669 | Processes For Production of Phenolic 4-Biphenylylazetidin-2-Ones - The present invention relates to processes for the production of phenolic 4-biphenylylazetidin-2-one derivatives of formula | 08-21-2008 |
