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Metabasis Therapeutics, Inc.

Metabasis Therapeutics, Inc. Patent applications
Patent application numberTitlePublished
20120093729NOVEL PHOSPHORUS-CONTAINING PRODRUGS - Novel cyclic phosphoramidate prodrugs of drugs of formula I04-19-2012
20120046364Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use - The present invention relates to sulfonic acid containing compounds of formula IB, in which G, R02-23-2012
20120039845NUCLEOSIDE PRODRUGS AND USES THEREOF - Compounds having the formula I or II, wherein R02-16-2012
20110294758NOVEL ACTIVATORS OF GLUCOKINASE - The present invention provides for novel compounds of Formulas I and II and pharmaceutically acceptable salts and co-crystals thereof which have glucokinsae activator activity. The present invention further provides for pharmaceutical compositions comprising the same as well as methods of treating, preventing, delaying the time to onset or reducing the risk for the development or progression of a disease or condition for which one or more glucokinase activator is indicated, including Type 1 and 2 diabetes, impaired glucose tolerance, insulin resistance and hyperglycemia. The present invention also provides for processes of making the compounds of Formulas I and II, including salts and co-crystals thereof, and pharmaceutical compositions comprising the same.12-01-2011
20110009356NOVEL PHOSPHORUS-CONTAINING PRODRUGS - Novel cyclic phosphoramidate prodrugs of drugs of formula I01-13-2011
20100081634Novel Phosphorus-Containing Thyromimetics - The present invention relates to compounds of phosphonic acid-containing T3 mimetics and monoesters thereof, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as well as their preparation and uses for preventing and/or treating metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndrome x and diabetes.04-01-2010
20090232879Thyromimetics for the Treatment of Fatty Liver Diseases - The present invention is directed toward the use of thyromimetic compounds that are thyroid receptor ligands, pharmaceutically acceptable salts thereof, and to prodrugs of these compounds for preventing, treating, or ameliorating fatty liver diseases such as steatosis, non-alcoholic fatty liver disease, and non-alcoholic steatohepatitis.09-17-2009
20090131370Novel Nucleoside Derivatives - Compounds of Formulae I-XVI, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of viral diseases including hepatitis C viral infection, cancer, diabetes, and other diseases are described: formula (I).05-21-2009

Patent applications by Metabasis Therapeutics, Inc.