| Medivir AB Patent applications |
| Patent application number | Title | Published |
|---|
| 20120123119 | ACYCLIC NUCLEOSIDE DERIVATIVES - Methods and novel intermediates for the preparation of and the treatment with acyclic nucleoside derivatives of the formula: | 05-17-2012 |
| 20120115807 | COMBINATION OF ALOVUDINE AND ZIDOVUDINE IN A MOLAR RATIO OF 1:100 TO 1:350 - Co-administration of alovudine and zidovudine at ratios considerably in excess of the prior art completely or substantially abolishes the mitochondrial toxicity of alovudine in mitochondrial DNA depletion experiments. The invention thus provides pharmaceutical compositions comprising alovudine and zidovudine in a molar ratio in the range 1:100 to 1:350 and methods for the treatment or prophylaxis of multiply resistant HIV comprising the simultaneous or consequential administration of alovudine and zidovudine in the characteristic molar ratio. | 05-10-2012 |
| 20120015994 | (2,5-DIOXOIMIDAZOLIDIN-I-YL)-N-HYDROXY-ACETAMIDES AS METALLOPROTEINASE INHIBITORS - The invention provides compounds of the formula (I) | 01-19-2012 |
| 20110230436 | Uracyl Cyclopropyl Nucleotides - Compounds of the formula I: | 09-22-2011 |
| 20110172410 | ANTIVIRAL NUCLEOSIDES - 4-Amino-1-((2R,3S,4S,5R)-5-azido-4-hydroxy-5-hydroxymethyl-3-methyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one (22) and prodrugs thereof are hepatitis C(HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting HCV and treating HCV-mediated diseases, processes for making the compounds and synthetic intermediates employed in the process. | 07-14-2011 |
| 20110112294 | 1-[2', 3' -DIDEOXY-3' C- (HYDROXYMETHYL) - BETA-D-ERYTHRO-PENTOFURANOSYL] CYTOSINE DERIVATIVES AS HIV INHIBITORS - Compounds of the formula I | 05-12-2011 |
| 20110112089 | Cysteine Protease Inhibitors - A compound of the formula II | 05-12-2011 |
| 20110105524 | CYSTEINE PROTEASE INHIBITORS - Compounds of the formula II: | 05-05-2011 |
| 20110092460 | CYCLOPROPYL POLYMERASE INHIBITORS - Compounds of formula I: | 04-21-2011 |
| 20110039862 | Protease Inhibitors - Compounds of the formula II: | 02-17-2011 |
| 20110021459 | DUTPASE INHIBITORS - Deoxyuridine derivatives of the formula | 01-27-2011 |
| 20110015148 | ANTIVIRAL NUCLEOSIDES - 4-Amino-1-((2R,3S,4S,5R)-5-azido-4-hydroxy-5-hydroxymethyl-3-methyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one (22) and prodrugs thereof are hepatitis C (HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting HCV and treating HCV-mediated diseases, processes for making the compounds and synthetic intermediates employed in the process. | 01-20-2011 |
| 20100166706 | HCV NS-3 SERINE PROTEASE INHIBITORS - Methods drawn to peptidomimetic compounds which inhibit the NS3 protease of the hepatitis C virus (HCV), are described. The compounds have the formula (VI) where the variable definitions are as provided in the specification. The compounds comprise a carbocyclic P2 unit in conjunction with a novel linkage to those portions of the inhibitor more distal to the nominal cleavage site of the native substrate, which linkage reverses the orientation of peptidic bonds on the distal side relative to those proximal to the cleavage site. | 07-01-2010 |
| 20100130735 | ANTIVIRAL NUCLEOSIDES - 4-Amino-1-((2R,3S,4S,5R)-5-azido-4-hydroxy-5-hydroxymethyl-3-methyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one (22) and prodrugs thereof are hepatitis C(HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting HCV and treating HCV-mediated diseases, processes for making the compounds and synthetic intermediates employed in the process. | 05-27-2010 |
| 20100075924 | DUTPASE INHIBITORS - Deoxyuridine derivatives of the formula | 03-25-2010 |
| 20100041728 | HCV INHIBITING MACROCYCLIC PHENYLCARBAMATES - Compounds of the formula 1: | 02-18-2010 |
| 20100003216 | HCV NS-3 Serine Protease Inhibitors - Compounds of the formula | 01-07-2010 |
| 20090281140 | Macrocyclic inhibitors of hepatitis c virus - Inhibitors of HCV replication of formula (I) | 11-12-2009 |
| 20090270429 | ANTIVIRAL FORMULATION - A topical antiviral composition comprising acyclovir, penciclovir and/or omaciclovir in a glucocorticoid-free pharmaceutical carrier comprising 15 to 25 weight % propylene glycol and 10 to 25 weight % isopropyl C | 10-29-2009 |
| 20090215846 | (2,5-DIOXOIMIDAZOLIDIN-I-YL)-N-HYDROXY-ACETAMIDES AS METALLOPROTEINASE INHIBITORS - The invention provides compounds of the formula (I) wherein the variables are as defined in the specification. The compounds of the invention are inhibitors of metalloproteinase MMP-12 and are among other things useful for the treatment of obstructive airway diseases, such as chronic obstructive pulmonary disease (COPD). | 08-27-2009 |
| 20090076041 | ACYCLIC NUCLEOSIDE DERIVATIVES - Methods and novel intermediates for the preparation of and the treatment with acyclic nucleoside derivatives of the formula: | 03-19-2009 |
| 20090023758 | Macrocyclic Inhibitors of Hepatitis C Virus - Compounds of the formula (I): and N-oxides, salts and stereoisomers thereof wherein A is OR | 01-22-2009 |
