| MEDICURE INTERNATIONAL INC. Patent applications |
| Patent application number | Title | Published |
|---|
| 20120029447 | TRANSDERMAL PHARMACEUTICAL PREPARATION AND ADMINISTRATION OF TIROFIBAN - The present invention provides a titratable transdermal drug delivery system comprising an effective dose of an antithrombotic agent, such as tirofiban, or a pharmaceutically acceptable salt thereof. The dosage of the drug delivered is proportional to the size of the patch applied and achieves 60-85% platelet inhibition. The system enables and individualized treatment for patients. Also provided are methods for the treatment of various disorders where platelet inhibition is desired. | 02-02-2012 |
| 20090215727 | INHIBITION OF ATP-MEDIATED, P2X7 DEPENDENT PATHWAYS BY PYRIDOXAL-5-PHOSPHATE AND VITAMIN B6 RELATED COMPOUNDS - P5P can be used as effective treatments for the modulation of P2X7, IL-1β, and inflammation response, and for diseases in which prevention of P2X7-dependent pathways or prevention of release of IL-1β is desirable, such as epithelial cancer, leukemia, brain tumors, spinal cord injury, tuberculosis, Alzheimer's Disease, neurodegenerative diseases, autosomal recessive polycystic kidney disease, diabetes, including type I diabetes, prostate cancer, and osteoporosis, bone formation and resorption. | 08-27-2009 |
| 20090018106 | INTRAVENOUS FORMULATIONS OF PYRIDOXAL 5'- PHOSPHATE AND METHOD OF PREPARATION - The present invention provides a lyophilized formulation of pyridoxal 5′-phosphate and a method of making the same. The present invention also provides an injectable formulation of pyridoxal 5′-phosphate reconstituted from the lyophilized formulation. The present invention further provides uses of the lyophilized and injectable formulations. | 01-15-2009 |
| 20080306108 | Substituted Pyridoxines As Anti-Platelet Agents - Compounds with antiplatelet aggregation characteristics for the treatment of cardiovascular and cardiovascular related disease, are described. The methods are directed to administering pharmaceutical compositions comprising a pyridoxine analogue. | 12-11-2008 |
| 20080214504 | Vitamin B6 Related Compounds and Methods for Recovery From Trauma - The present invention includes a method of promoting recovery from trauma in a patient in need thereof comprising administration of a therapeutically effective amount of a vitamin B6 related compound (excluding vitamin B6), preferable compounds include pyridoxal-5′-phosphate, 3-acylated analogues of pyridoxal, 3-acylated analogues of pyridoxy-4,5-animal, and pyridoxine phosphate analogues. | 09-04-2008 |
| 20080213364 | Formulations of Pyridoxal-5'-Phosphate and Methods of Preparation - The present invention provides pharmaceutical compositions for oral administration comprising pyridoxal-5′-phosphate wherein the compositions contain an amount of pyridoxal-5-phosphate of at least 50% w/w and methods of preparing the pharmaceutical compositions. The present invention also provides a pre-blend for the manufacture of a pyridoxal 5′-phosphate oral dosage form comprising pyridoxal 5′-phosphate and microcrystalline cellulose, wherein the pre-blend contains an amount pyridoxal-5-phosphate greater than or equal to 80% w/w. | 09-04-2008 |
