| MED INSTITUTE, INC. Patent applications |
| Patent application number | Title | Published |
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| 20120130470 | STENT WITH PROTECTED BARBS - An endoluminal prosthesis is described and comprises a stent ( | 05-24-2012 |
| 20110313512 | Side Branch Stent Graft - A stent graft has a tubular side arm which can be angled proximally and distally and from side to side. The wall of the stent graft in the vicinity of the side arm has a loose fold of the graft material and the side arm is fastened to the loose fold of graft material. The tubular side arm has an inner end and an outer end and is fastened into the loose fold of graft material by a circumferential fastening around the tubular side arm between the inner end and the outer end so that the tubular side arm extends partially within the tubular body of the stent graft and partially outside the tubular body of the stent graft. The loose fold of graft material can be formed by the graft material defining a recess in the wall of the stent graft. To enable movement or angulation proximally and distally and from side to side the loose fold of graft material is provided both proximally and distally of the tubular side arm and circumferentially to each side of the tubular side arm. | 12-22-2011 |
| 20110251588 | Infusion Mechanism And Method - An infusion mechanism for treating an intraluminal site in a patient includes an infusion catheter having an elongate body with a proximal body end defining at least one fluid supply orifice, and a distal body end. The elongate body defines a high head loss lumen in fluid communication with a first set of side ports defining a proximal infusion zone. The elongate body further defines a low head loss lumen in fluid communication with a second set of side ports defining a distal infusion zone. | 10-13-2011 |
| 20110196479 | COATED IMPLANTABLE MEDICAL DEVICE - A coated implantable medical device includes a structure adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer posited on one surface of the structure; and at least one layer of a bioactive material posited on at least a portion of the coating layer. Preferably the structure is a stent graft. | 08-11-2011 |
| 20110160844 | INTRAVASCULAR DEVICE ATTACHMENT SYSTEM HAVING BIOLOGICAL MATERIAL - An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system includes an intravascular device and biological attachment material connected to the intravascular device. The biological attachment material is configured to attach the intravascular device to the vessel wall. | 06-30-2011 |
| 20110153007 | Taxane Coatings for Implantable Medical Devices - This disclosure relates to implantable medical devices coated with a taxane therapeutic agent, such as paclitaxel, in one or more solid form(s) having varying dissolution rates. Particularly preferred coatings comprise amorphous and/or solvated solid forms of taxane therapeutic agents that provide durable coatings that release the taxane over a desired period of time, which can be varied in the absence of a polymer by selecting the type and amount of solid forms of the taxane therapeutic agent in the coating. Other preferred embodiments relate to methods of coating medical devices and methods of treatment. The coatings can provide a sustained release of the taxane therapeutic agent within a body vessel without containing a polymer to achieve the desired rate of paclitaxel elution. | 06-23-2011 |
| 20110144689 | Occlusion Device - An occlusion device includes a tubular expandable body with a frame that has a plurality of interconnected members configured to expand within a body vessel and to collapse for delivery or retrieval of the device. The occlusion device further includes a hydrophilic polyurethane hydrogel layer attached to the interconnected members of the tubular expandable body. The polyurethane hydrogel layer expands upon exposure to an aqueous environment. | 06-16-2011 |
| 20110125249 | Stent Graft and Introducer Assembly - A stent graft ( | 05-26-2011 |
| 20110118821 | LOW PROFILE NON-SYMMETRICAL STENT - Various stents and stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system may comprise proximal and distal components, each comprising a graft having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component may comprise a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices may be greater than the radius of curvature of at least one of the distal apices. The distal component may comprise a proximal z-stent coupled to the graft, where the proximal end of the graft comprises at least scallop formed therein that generally follows the shape of the proximal z-stent. Further, the distal component may comprise at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component. | 05-19-2011 |
| 20110106120 | INTRAVASCULAR DEVICE ATTACHMENT SYSTEM HAVING TUBULAR EXPANDABLE BODY - An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system includes a tubular expandable body defining a lumen therethrough. The tubular expandable body is configured to move between an expanded state to contact the body vessel and a collapsed state for delivery or retrieval. The tubular expandable body is configured to contact the vessel wall along the length of the tubular expandable body in the expanded state when deployed in the body vessel. An intravascular device is held to the exterior side of the tubular expandable body and is configured to contact the vessel wall when the tubular expandable body is in the expanded state and the system is deployed within a body vessel. | 05-05-2011 |
| 20110106115 | INTRAVASCULAR DEVICE ATTACHMENT SYSTEM HAVING STRUTS - An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system has an intravascular device having a first end and a second end. The intravascular device defines a longitudinal axis along a length thereof. Several struts are connected to one or more ends of the intravascular device. Each strut is configured to move along a strut path relative to the longitudinal axis between an expanded state for engaging the vessel wall and a collapsed state for delivery or retrieval. Each strut has a free end configured to engage the vessel wall in the expanded state. | 05-05-2011 |
| 20110009945 | METHOD FOR DEPLOYING A STENT DELIVERY SYSTEM HAVING A BLOWMOLDED HOLDER - A method for deploying a stent delivery system having a blowmolded holder is provided. The stent is configured to expand from a first diameter to a second diameter. The holder is blowmolded to an inner surface of the compressed state. The holder contacts the inner surface and at least portions of side surfaces of the stent, and the holder and the stent have an interference fit therebetween. The deployment method includes delivering the compressed stent placed on the blowmolded holder and the holder into a predetermined deployment side. The deployment method further includes releasing the stent from interference with the holder and expanding the stent from the compressed stent to the expanded stent. | 01-13-2011 |
| 20110009848 | FLUID INJECTION DEVICE - A medical device is provided. The device includes a cannula with a lumen defined therethrough and an upper portion, a right side portion, a bottom portion, and a left side portion each substantially equally spaced from their respective neighboring portion around the circumferential surface of the cannula. The cannula additionally includes a plurality of apertures disposed through the distal end portion to provide communication from the lumen and a visually perceptible indicator that is configured to allow the cannula to be positioned at an appropriate rotational position within the patient. A plurality of injection needles are disposed within the lumen and a first handle is fixed with respect to the cannula and a second handle is disposed in conjunction with the first handle and fixed to the proximal portion of each of the plurality of needles, the first handle is translatable with respect to the second handle to translate the plurality of needles from a first position where the distal portions of each of the plurality of needles are disposed within the lumen of the cannula, and a second position where the distal portion of each of the plurality of needles extends out of the lumen through their respective aperture. | 01-13-2011 |
| 20100323052 | NEEDLE-TO-NEEDLE ELECTROSPINNING - The disclosure relates to a method and apparatus for coating a medical device. The method includes providing an electrospinning apparatus and simultaneously electrospinning at least one solution onto a first surface and an opposing second surface. The apparatus comprises a first spinneret and a second spinneret. An energy source is electrically coupled to the first spinneret and the second spinneret. The first spinneret and second spinneret comprise a reservoir and an orifice fluidly coupled to the reservoir. The first spinneret orifice is located substantially opposite the second spinneret orifice. | 12-23-2010 |
| 20100292778 | EXPANDABLE STENT COMPRISING END MEMBERS HAVING AN INTERLOCKING CONFIGURATION - An expandable stent for use in a body vessel comprises a thin-walled tubular framework including two or more circumferentially adjacent end members extending in a longitudinal direction from an end of the framework. In a delivery configuration of the tubular framework, the end members have an interlocking configuration. Each end member has a first interlocking side and a second interlocking side, where the first interlocking side has a circumferentially directed protrusion and the second interlocking side has a circumferentially directed recess. The protrusion of a first end member mates with the recess of a second end member. In an expanded configuration of the tubular framework, the end members are disengaged from the interlocking configuration. Each end member may be an eyelet including an opening for a radiopaque rivet. A method of preparing the expandable stent for delivery into a body vessel is also described. | 11-18-2010 |
| 20100249899 | PARARENAL STENT GRAFT - A stent graft for endovascular introduction into the pararenal region of the descending aorta. The stent graft has an elongate tubular body ( | 09-30-2010 |
| 20100161027 | STENT AND STENT-GRAFT HAVING ONE OR MORE CONFORMANCE STRUTS - A stent includes a main body having proximal and distal ends, and at least one conformance strut coupled to the proximal end of the main body. A portion of the at least one conformance strut extends proximal to a proximal end of a graft material in a compressed delivery configuration, and further is aligned inside the proximal end of the graft material in an expanded deployed configuration. In the deployed configuration, the proximal conformance strut may at least partially encircle the graft material just distal to the proximal end of the graft material, which may reduce the likelihood of infolding at the proximal edge of the graft material and potential endoleaks. | 06-24-2010 |
| 20100152835 | Tapered Stent and Flexible Prosthesis - The disclosure relates to a tapered stent and flexible prosthesis. The stent has a first longitudinal region and a second longitudinal region. The second region is substantially parallel to and spaced axially apart from the first region. A plurality of struts is disposed intermediate the first region and the second region and circumferentially connects the first region and the second region. The first region has a longitudinal length that is greater than the second region longitudinal length. The struts have varying longitudinal lengths that gradually decrease from the first region to the second region. The flexible prosthesis comprises at least two alternating tapered stents. | 06-17-2010 |
| 20100148409 | METHOD FOR MANUFACTURING A STENT DELIVERY SYSTEM - A method for manufacturing a stent delivery system having a holder and at least one stent configured to expand from a first diameter to a second diameter is provided. The manufacturing method includes compressing the stent to the first diameter, inserting the stent into a first tube, placing a second tube inside the first tube and inside an inner diameter of the stent. The second tube is airtight. The manufacturing method also includes applying pressure and heat suitable to the second tube, thereby blowmolding the second tube against the stent. | 06-17-2010 |
| 20100106257 | GRAFT PROSTHESIS, MATERIALS AND METHODS - A graft prostheses ( | 04-29-2010 |
| 20100106256 | GRAFT PROSTHESIS, MATERIALS AND METHODS - A graft prostheses ( | 04-29-2010 |
| 20100104658 | GRAFT PROSTHESIS, MATERIALS AND METHODS - A graft prostheses ( | 04-29-2010 |
| 20100104617 | GRAFT PROSTHESIS, MATERIALS AND METHODS - A graft prostheses ( | 04-29-2010 |
| 20100049296 | Implantable medical device coatings with biodegradable elastomer and releasable taxane agent - A coated medical device, such as a stent, that elutes a taxane agent in a controlled manner is provided. In one embodiment, the taxane agent is paclitaxel and at least a portion of the paclitaxel is present in a dihydrate solid form. The medical device may be coated with a layer including a taxane agent and a layer of bioabsorbable elastomer over the layer including the taxane agent. Methods of manufacturing and using the coated medical device are also provided. | 02-25-2010 |
| 20100016953 | Anchoring Barb for Attachment to a Medical Prosthesis - Disclosed is an anchoring element for an implantable prosthesis that includes a barb, wherein the anchoring element, which includes a basal portion, comprises a thin layer of material, such as a cannula or sheet of metal, that extends or wraps at least partially around the strut of the prosthesis to which it is attached. The barb is configured to extend outward from the basal portion to penetrate adjacent tissue. The anchoring element is either permanently affixed to the strut, such as by laser or spot welding, crimping, or some other method of bonding, or allowed to slide longitudinally over the strut between two points or stops in order to relieve any excessive loads placed upon the barb that could cause fracture. The anchoring element and strut may be configured to limit axial rotation of the barb, while still allowing longitudinal movement. In another embodiment, the slidable anchoring element may be manipulated following initial deployment to reorient the barb toward the implantation site. | 01-21-2010 |
| 20090258050 | Controlled Drug Delivery Using a Zein Layer Modified with Levulinic Acid - The disclosure relates to medical devices coated with zein admixed with levulinic acid. The medical device may further include a therapeutic agent in contact with zein admixed with levulinic acid. Zein admixed with levulinic acid allows the therapeutic agent to be retained on the device during delivery and also controls the elution rate of the therapeutic agent following implantation. The disclosure further relates to methods of delivering a therapeutic agent on said medical devices as well as their use especially in the form of stents for prevention of restenosis. | 10-15-2009 |
| 20090248144 | ENDOLUMINAL DEVICE WITH EXTRACELLULAR MATRIX MATERIAL AND METHODS - An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material. The bioremodelable material is disposed on an exterior surface in at least one band adjacent at least one of the proximal and distal openings. | 10-01-2009 |
| 20090248134 | STENT WITH POLISHED EYELET - A stent for use in a stent graft comprising a strut region comprising at least two struts, the struts having at least one radius of curvature; a bend connecting the at least two struts and forming an eyelet region, where the strut region and the eyelet region are electropolished and the eyelet region is locally polished; and an eyelet positioned in the eyelet region, having at least one radius of curvature greater than zero is provided. A method of manufacturing the same also is provided. | 10-01-2009 |
| 20090204202 | STENT DESIGNS FOR USE WITH ONE OR MORE TRIGGER WIRES - The present embodiments provide a stent for use in a medical procedure that comprises a series of proximal apices disposed at a proximal end of the stent and a series of distal apices disposed at a distal end of the stent. A trigger wire is adapted to be coupled to at least one of the proximal apices to restrain a proximal end of the stent during delivery. In a first embodiment, a first proximal apex comprises a bore for receiving the trigger wire, and a second proximal apex, disposed adjacent to the first proximal apex, comprises at least one barb. The trigger wire therefore is only coupled to selected ones of the proximal apices. In an alternative embodiment, a first proximal apex comprises a first bore and a second, adjacent proximal apex comprises a second bore, such that a single trigger wire may be disposed through the first and second bores to restrain the first and second proximal apices during delivery. | 08-13-2009 |
| 20090171451 | IMPLANTABLE DEVICE HAVING COMPOSITE WEAVE - An implantable device having a composite weave graft is disclosed. The device comprises a graft body forming a lumen defining a longitudinal axis and comprising proximal and distal ends. The graft body comprises a composite of low dernier yarns and polymeric yarns configured for low profile delivery and radial elongation relative to the longitudinal axis during use. The graft body has a first portion and a second portion extending from the first portion. The first portion comprises at least one expandable stent radially attached thereto for support and the second portion having corrugations for enhanced kink resistance. | 07-02-2009 |
| 20090171437 | LOW PROFILE NON-SYMMETRICAL STENT - A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition. | 07-02-2009 |
| 20090151819 | METHOD FOR BONDING COMPONENTS OF MEDICAL DEVICES - A method of bonding a first component of a medical device to a second component of the medical device, where at least one of the components comprises a shape memory material, includes positioning the components in close proximity to each other to obtain an assembled configuration, and heating the assembled configuration at a temperature in the range of from about 800° C. to about 1100° C. to obtain a diffusion bond at a region of contact between the two components. The assembled configuration is formed into a desired set shape and heat-set at a temperature in the range of from about 350° C. to about 550° C. to impart a memory of the desired set shape to the shape memory materials without substantially impairing the diffusion bond. | 06-18-2009 |
| 20090149938 | Lubrication Apparatus for a Delivery and Deployment Device - A delivery and deployment device comprises a sheath having a proximal end, a distal end, and a lumen disposed therebetween; a dilator having a distal end slidingly disposed within the sheath lumen; a valve assembly comprising a valve housing affixed to the sheath and a valve disposed within the housing between the sheath and the dilator; and a valve lubrication mechanism disposed between the valve and the dilator. | 06-11-2009 |
| 20090142505 | Needle-to-Needle Electrospinning - The disclosure relates to a method and apparatus for coating a medical device. The method includes providing an electrospinning apparatus and simultaneously electrospinning at least one solution onto a first surface and an opposing second surface. The apparatus comprises a first spinneret and a second spinneret. An energy source is electrically coupled to the first spinneret and the second spinneret. The first spinneret and second spinneret comprise a reservoir and an orifice fluidly coupled to the reservoir. The first spinneret orifice is located substantially opposite the second spinneret orifice. | 06-04-2009 |
| 20090105797 | EXPANDABLE STENT - A stent includes a radially expandable tubular structure having a first end, a second end, and a primary strut arrangement extending over substantially an entire length thereof. The primary strut arrangement includes a plurality of rows of struts. The struts are interconnected within each row in a sinusoidal arrangement about a circumference of the tubular structure. Crests and troughs in the sinusoidal arrangement include connection points of the struts. A plurality of longitudinal struts connect neighboring rows of struts at the connection points. In each row, four circumferentially adjacent struts are disposed between every two longitudinal struts joined to the row. One of the two longitudinal struts extends in a direction of the first end to a first neighboring row, and the other of the two longitudinal struts extends in a direction of the second end to a second neighboring row. | 04-23-2009 |
| 20090099638 | MOTORIZED DEPLOYMENT SYSTEM - A motorized delivery system and method for deploying an endoluminal prosthesis is disclosed. The system comprises a delivery device and an electrical drive system. The prosthesis is disposed between an inner dilator and an elongate sheath. To deploy the prosthesis, the electrical drive system is actuated. One or more gear-pulley arrangements rotate to cause retraction of the sheath in relation to the inner dilator. | 04-16-2009 |
| 20090061072 | MANDREL AND METHOD FOR COATING OPEN-CELL IMPLANTABLE ENDOVASCULAR STRUCTURES - Methods of coating a medical device are provided to improve coating uniformity and reduce coating irregularities while reducing direct coating of the luminal surface of the medical device. Preferably, methods of coating a tubular medical device include the steps of: positioning the tubular medical device around a mandrel coating assembly, mounting the tubular medical device on the mandrel coating assembly and spraying a coating solution including a therapeutic agent and a solvent onto the abluminal surface of the tubular medical device mounted on the mandrel coating assembly. The mandrel coating assembly may include an axial member of a diameter that is less than the diameter of the lumen of the tubular medical device and at least one annular projection extending from the axial member to an outer surface having a diameter greater than or substantially equal to the diameter of the lumen of the medical device. Improved coating uniformity may be achieved by providing an annular space between the luminal surface of the medical device and an axial member. Coating on the luminal surface may be minimized by providing an axial member having an outer diameter that is greater than the maximum width or length of the spray contacting the axial member after passing through the openings in the medical device. | 03-05-2009 |
| 20090024137 | Prosthesis Delivery and Deployment Device - A device for delivering and deploying a prosthesis is described and comprises an elongate sheath having a sheath lumen and a delivery catheter slidably disposed within the sheath lumen. A deployment assist mechanism may be coupled to the delivery catheter and the sheath and configured to apply a retraction force to the delivery catheter and the sheath. Additional devices, systems, and methods of delivering and deploying a prosthesis are described. | 01-22-2009 |
| 20080286325 | CYCLODEXTRIN ELUTION MEDIA FOR MEDICAL DEVICE COATINGS COMPRISING A TAXANE THERAPEUTIC AGENT - The present disclosure provides methods of measuring the release of a taxane therapeutic agent from a medical device as a function time in contact with a suitable elution medium. The method preferably comprises the step of contacting a coated medical device comprising a taxane therapeutic agent with an elution medium comprising a cyclodextrin to provide an elution profile indicative of the composition or configuration of a medical device coating comprising a taxane therapeutic agent. The elution profile can provide information about the medical device coating that is useful in lot release testing. | 11-20-2008 |
| 20080243103 | Medical Device for Delivering a Bioactive and Method of Use Thereof - A device and method for delivering a bioactive to the uterine wall. In one embodiment, the device comprises a balloon having the bioactive present within the material of the balloon or on an outside surface of the balloon. Another embodiment provides a method comprising inserting the balloon into the uterus, inflating the balloon so that the outside surface of the balloon exerts pressure on uterine wall and delivering the bioactive to the uterine wall. | 10-02-2008 |
