| 20080255767 | Method and Device For Detection of Splice Form and Alternative Splice Forms in Dna or Rna Sequences - The invention relates to a method and a device for detection of splice sites in DNA or RNA sequences comprising three steps: a) examining a training set of sequences comprising DNA or RNA sequences with known splice sites by an automated, discriminative training device for detecting splicing patterns, especially in a predetermined window around the known splice sites; b) scanning a sequence comprising DNA or RNA sequences containing unknown splice sites for the occurrence of the splicing patterns detected in step a); and c) calculation of a cumulative splice score in dependence of a maximization of the margin between the true splice forms and all wrong splice forms in the sequence. The invention also relates to a method and a device for detection of splice forms and alternative splice forms in DNA or RNA sequences. | 10-16-2008 |
