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MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (MED) BERLIN-BUCH

MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (MED) BERLIN-BUCH Patent applications
Patent application numberTitlePublished
20100104556EPITOPE-TAG FOR SURFACE-EXPRESSED PROTEINS AND USES THEREOF - The present invention relates to a method for selecting a host cell population expressing a functional fusion protein comprising at least one epitope-providing amino acid sequence (epitope-tag) and the amino acid sequence of a protein that is expressed on the surface of said host cell. Preferably, the amino acid sequence comprises an alpha or beta chain of a T-cell receptor. The present invention further relates to uses of said functional T-cell receptor (TCR) alpha or beta chain fusion protein in medicine, in particular in adoptive transfer.04-29-2010