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MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN

MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN Patent applications
Patent application numberTitlePublished
20110189141MULTIPLE TARGET T CELL RECEPTOR - The present invention is directed to a functional T cell receptor (TCR) fusion protein (TFP) recognizing and binding to at least one MHC-presented epitope, and containing at least one amino acid sequence recognizing and binding an antigen. The present invention is further directed to an isolated nucleic acid molecule encoding the same, a T cell expressing said TFP, and a pharmaceutical composition for use in the treatment of diseases involving malignant cells expressing said tumor-associated antigen.08-04-2011