| MASSACHUSETTS EYE & EAR INFIRMARY Patent applications |
| Patent application number | Title | Published |
|---|
| 20120123383 | VESTIBULAR STIMULATOR - A method for providing relief from Meniere's disease, includes reversibly disabling vestibular function following detection of an attack of Meniere's disease following detection of an attack of Meniere's disease. | 05-17-2012 |
| 20120000474 | VESTIBULAR CANAL PLUG - An apparatus to reduce the sensitivity of the vestibular system to stimulation. The apparatus comprises a plugging device configured to constrain the movement of endolymph fluid within a semicircular canal, and a control module coupled to the plugging device that causes the plugging device to maintain a set actuated position. | 01-05-2012 |
| 20110305674 | Pathways to Generate Hair Cells - This disclosure relates to methods and compositions for modulating (e.g., increasing) Atoh1 activity (e.g., biological activity) and/or expression (e.g., transcription and/or translation) in vivo and/or in vitro, e.g., in a biological cell and/or in a subject. The methods and compositions described herein can be used in the treatment of diseases and/or disorders that would benefit from increased Atoh1 expression in a biological cell. | 12-15-2011 |
| 20110184703 | SENSOR SIGNAL ALIGNMENT - Methods and systems, including computer readable mediums, are provided for transforming a measurement made relative to a first reference frame into a corresponding measurement relative to a second reference frame. Sensor signals that are produced by sensors in response to the sensors' motion relative to the first reference frame are transformed using a transformation matrix. The transformation generates corrected sensor signals that are relative to the axes of the second reference frame. | 07-28-2011 |
| 20110092843 | AERODYNAMIC TISSUE DRIVER - A method for assessing mechanical properties of a selected tissue includes defining an expansion chamber adjacent to the selected tissue and passing pressurized air into the expansion chamber. The method also includes providing an opening through which the pressurized air can escape the expansion chamber, the opening being disposed such that, while escaping from the expansion chamber, air passes by the selected tissue, thereby causing the selected tissue to vibrate. | 04-21-2011 |
| 20110054356 | VESTIBULOGRAM - An apparatus for determining a subject's threshold for perceiving acceleration includes a motion platform to execute motions and to receive a response to the executed motions from a subject on the motion platform and a feedback system in communication with the motion platform to receive the subject's responses, and to determine a next motion. The next motion has at least one feature determined based on the response of the subject to the executed motions. The apparatus also includes a controller connected to the motion platform and the feedback system to cause the motion platform to execute the motions defined by a motion set | 03-03-2011 |
| 20100203029 | LYSYL OXIDASE-LIKE 1 (LOXL1) AND ELASTOGENESIS - Described are methods of treating and preventing conditions associated with a loss of elastic fibers. Also provided herein are methods of screening for agents useful in treating such conditions, and animal models of conditions associated with a loss of elastic fibers. | 08-12-2010 |
| 20100179631 | SENSOR SIGNAL ALIGNMENT - Methods and systems, including computer readable mediums, are provided for transforming a measurement made relative to a first reference frame into a corresponding measurement relative to a second reference frame. Sensor signals that are produced by sensors in response to the sensors' motion relative to the first reference frame are transformed using a transformation matrix. The transformation generates corrected sensor signals that are relative to the axes of the second reference frame. | 07-15-2010 |
| 20090232780 | COMPOUNDS THAT ENHANCE ATOH1 EXPRESSION - This invention generally provides compounds, pharmaceutical compositions, and methods for their use, which include methods that result in increased expression in an Atoh1 gene (e.g., Hath1) in a biological cell. More specifically, the invention relates to the treatment of diseases and/or disorders that would benefit from increased Atoh1 expression, e.g., a hearing impairment or imbalance disorder associated with a loss of auditory hair cells, or a disorder associated with abnormal cellular proliferation. | 09-17-2009 |
| 20090159086 | CRICOTHYROTOMY DEVICE - A cricothyrotomy syringe has a hollow body, a needle connector at an end of the body, an aperture at an opposite end of the body, a plunger in the aperture, the plunger having a seal that forms a liquid tight seal with an inner surface of the body and the plunger moveable within the body between an extended position and a compressed position and a ventilator adaptor extending from a side of the body, where an interior of the ventilator adaptor is in fluid communication with an interior of the body when the plunger is in the extended position. | 06-25-2009 |
| 20090098093 | GENERATION OF INNER EAR CELLS - Methods for generating cells of the inner ear, e.g., hair cells and supporting cells, from stem cells, e.g., mesenchymal stem cells, are provided, as well as compositions including the inner ear cells. Methods for the therapeutic use of the inner ear cells for the treatment of hearing loss are also described. | 04-16-2009 |
| 20090082859 | POLARIZATION-SENSITIVE VISION PROSTHESIS - A vision prosthesis includes a first detector disposed to detect a polarization state of light reflected from a retina, and a controller in communication with the first detector. The controller is configured to receive, from the detector, a measurement signal indicative of the polarization state. In response thereto, the controller generates a control signal for causing a change to an optical property of an optical system in optical communication with the retina. | 03-26-2009 |
| 20080249621 | VISION PROSTHESIS ORIENTATION - A vision prosthesis includes an optical element having a surface that is shaped to be positioned near a cornea of an eye, and a magnetic element embedded in the optical element. | 10-09-2008 |
