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MARINUS PHARMACEUTICALS, INC.

MARINUS PHARMACEUTICALS, INC. Patent applications
Patent application numberTitlePublished
20110040112METHOD FOR MAKING 3A-HYDROXY, 3B- SUBSTITUTED-5A-PREGNAN-20-ONES - Applicants have discovered a method for the stereoselective and regioselective synthesis of 3α-hydroxy, 3β-methyl-5α-pregnan-20-one (ganaxolone) comprising reacting 5α-pregnane-3,20-dione; with an organometallic methylating agent in an inert solvent to provide a compound of the formula02-17-2011