LONZA COLOGNE GmbH Patent applications |
Patent application number | Title | Published |
20160030482 | COMPOSITIONS AND METHODS FOR ENHANCING THE THERAPEUTIC POTENTIAL OF STEM CELLS - The invention encompasses compositions and method of treating a vascular disease such as peripheral artery disease, The methods involveāadministering to a patient in need thereof, an effective amount of a composition comprising a population of cells such as mesenchymal stem cells (MSCs) and a non-muscle myosin 0 antagonist such as blebbistatin. Non-muscle myosin II antagonists are disclosed to surprisingly and dramatically accelerate MSC-triggered regeneration of damaged tissues arid unexpectedly and drastically reduce severe complications of stem cell treatment. | 02-04-2016 |
20130295669 | METHOD FOR CONTROLLING BINDING OF CELLS TO A SUBSTRATE - The invention relates to a method for promoting the adhesion of cells to a substrate to which these cells usually have no or only low affinity, wherein the adhesion of the cells to the substrate is promoted by supplying the cells with the non-muscle myosin II inhibitor Blebbistatin so as to enable the cells to attach to surfaces to which they otherwise would not have sufficient affinity. Surprisingly, supplying the cells with the inhibitor enhances the capability of these cells to attach to surfaces to which they usually have no or only low affinity, for example, PTFE (TeflonĀ®). The invention further concerns uses of the non-muscle myosin II inhibitor Blebbistatin and devices having at least one surface which is coated with cells that have no or only low affinity to said surface. | 11-07-2013 |
20130260434 | METHOD AND ELECTRODE ASSEMBLY FOR TREATING ADHERENT CELLS - The invention relates to an electrode assembly | 10-03-2013 |
20130230895 | METHOD AND DEVICE FOR UNIFORMLY TREATING ADHERENT CELLS - The invention relates to a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes | 09-05-2013 |
20120087841 | CONTAINER WITH A PLURALITY OF REACTION SPACES AND ELECTRODES - The invention relates to a container ( | 04-12-2012 |
20120077245 | METHOD AND DEVICE FOR THE ELECTRICAL TREATMENT OF REACTION SPACES - The invention relates to a method for applying at least one electrical voltage pulse to at least one reaction space by at least partially discharging at least one charge storing unit for storing electrical charges. According to the invention the method comprises applying at least one voltage pulse to a reaction space by at least partially discharging a second charge storing unit and simultaneously charging or partially discharging a first charge storing. Furthermore, the invention relates to a device | 03-29-2012 |
20120067639 | A METHOD AND A DEVICE FOR THE ELECTRICAL TREATMENT OF A PLURALITY OF CONTAINERS - The invention relates to a method for the application of at least one voltage pulse to at least two containers fitted with electrodes, by means of which at least one voltage pulse is applied to at least one container, while at least one other container is subjected to a preparation or a post-processing. According to the invention the method comprises mutual exchange of the respective positions of the container to which a voltage pulse has already been applied and the further container. Furthermore, the invention relates to a device ( | 03-22-2012 |