| LEICA BIOSYSTEMS NUSSLOCH GMBH Patent applications |
| Patent application number | Title | Published |
| 20120134894 | APPARATUS FOR HANDLING SPECIMEN SLIDES - An apparatus ( | 05-31-2012 |
| 20120134893 | APPARATUS FOR HANDLING SPECIMEN SLIDES - An apparatus ( | 05-31-2012 |
| 20120090726 | Method and Apparatus for Safety-Compliant Emptying and Filling of a Reagent Container - An apparatus for safety-compliant emptying and filling of a reagent container ( | 04-19-2012 |
| 20120009620 | Method for Reducing Entrainment in a Staining Device - During operation of a staining device ( | 01-12-2012 |
| 20120009101 | Automatic Calibration of a Staining Device - A sensor device ( | 01-12-2012 |
| 20120006807 | STAINING DEVICE HAVING AUTOMATIC MAINS VOLTAGE DETECTION AND VOLTAGE CHANGEOVER - A staining device for staining samples has a heating device including a first heating element and a second heating element. A switch arrangement allows the two heating elements to be connected in parallel or in series. A power connection supplies power to the heating elements. A sensor is designed and located to detect a current supplied to the heating elements. A switching unit is coupled to the sensor and determines a voltage causing the current. Depending on the voltage, the switching unit connects the heating elements in parallel or in series. | 01-12-2012 |
| 20120003679 | SENSOR MODULE, TISSUE PROCESSOR, AND METHOD FOR OPERATING A TISSUE PROCESSOR - A sensor module ( | 01-05-2012 |
| 20110265497 | Microtome Cassette Clamp Having An Air Channel For Dissipating The Heat Of A Cooling Element, And Microtome - A device for cooling a tissue sample on a microtome includes a cooling element ( | 11-03-2011 |
| 20110197731 | Vibrating Microtome With Automated Measurement Of Vertical Runout - In a vibrating microtome ( | 08-18-2011 |
| 20110114719 | System and Method for the Unequivocal Allocation of Histological Cassettes and Specimen Slides | 05-19-2011 |
| 20110091961 | Tissue Processor For Treating Tissue Samples - A tissue processor for treating tissue samples comprises a process chamber ( | 04-21-2011 |
| 20110087448 | Device For Processing Tissue Samples | 04-14-2011 |
| 20110045565 | APPARATUS AND METHOD FOR ACCELERATED TISSUE INFILTRATION BY MEANS OF MICROWAVE EXCITATION - A tissue infiltration apparatus, system and method are described, allowing accelerating infiltration of the tissue sample with a variety of reagents fluids. The apparatus comprises a reaction chamber adapted to receive a tissue sample and a dielectric fluid to be infiltrated into a tissue sample. The reaction chamber comprises a bottom and a circumferential wall with a window section that is transparent for microwave irradiation. A holding element holds the tissue sample over a predetermined time period at a distance of 3PD of the dielectric fluid from the window section is provided. PD is the penetration depth of the microwaves into the dielectric fluid and defined as the depth where the initial microwave field intensity has been reduced to 1/e. A microwave system irradiates microwave irradiation through the window section into the reaction chamber. | 02-24-2011 |
| 20110041599 | Method for Operating a Tissue Processor - A method for operating a tissue processor is described. During the operation of a tissue processor a reagent is fed from a container into a retort of the tissue processor, which retort does not contain any tissue samples. Thereafter, the reagent is returned into the container. During feeding, returning and/or in between feeding and returning a measured value is detected by a sensor of the tissue processor. This value is representative of a concentration of the reagent. During this feeding, this returning and/or in between no tissue sample is placed in the retort. | 02-24-2011 |
| 20100323395 | Method For Automatically Processing Tissue Samples In A Tissue Processor - In the automatic processing of tissue samples in a tissue processor, the tissue samples are placed in a retort of the tissue processor. The tissue samples are exposed to a fixation reagent (FIX) in the retort. Afterwards, the tissue samples are exposed to a dehydrating reagent (ALK). Thereafter, the retort is cleared with an intermedium (INT) for removing the dehydrating reagent (ALK). Finally, the tissue samples are treated with a carrier material (CAR). Between the clearing of the retort with the intermedium (INT) and the treatment of the tissue samples with the carrier material (CAR), the retort is cleared with a carrier material protecting reagent (CARPRO) in which the intermedium (INT) and the carrier material (CAR) can be mixed. | 12-23-2010 |
| 20100263390 | Freezing Microtome And Method For Producing Microscopable Thin Sections - A freezing microtome for the production of microscopable thin sections of tissue samples ( | 10-21-2010 |
| 20100248301 | Tissue Embedding Apparatus, And Method For Operating A Tissue Embedding Apparatus - The present invention relates to a tissue embedding apparatus ( | 09-30-2010 |
| 20100216222 | Tissue Infiltration Device - The present invention relates to a tissue infiltration device ( | 08-26-2010 |
| 20100216221 | DEVICE WITH WHICH A HISTOLOGICAL SECTION GENERATED ON A BLADE OF A MICROTOME CAN BE APPLIED TO A SLIDE - A device for applying a histological section to a slide is described. The histological section is generated by a cutting action performed by a blade of a microtome. The device comprises a positioning device having a component that is rotatably mounted to a bearing and has a receptacle for receiving and holding the slide, wherein the positioning device is designed such that the slide received in the receptacle can be rotated about an axis of rotation of the rotatably mounted component. | 08-26-2010 |
| 20100180742 | Device And Method For Braking A Shaft Of A Microtome - The present invention relates to a device for braking or locking a shaft ( | 07-22-2010 |
| 20100175525 | Device And Method For Controlling A Brake Of A Microtome - The present invention relates to a device for controlling a brake of a microtome. The microtome ( | 07-15-2010 |
| 20100170336 | Device For Treating Specimens And Method For Determining The Fill Level Of Reagent Containers - The invention relates to a device ( | 07-08-2010 |
| 20100147120 | Method For Automatically Feeding A Specimen To Be Thinly Cut To The Knife Of A Microtome - A method for the automatic and contact-free relative approach between a specimen ( | 06-17-2010 |
| 20100118133 | METHOD AND DEVICE FOR PRODUCING THIN SECTIONS OF A SAMPLE BY MEANS OF AN IMAGE RECOGNITION SYSTEM - A method and a device for producing thin sections of a sample by means of a microtome is described, in which a camera acquires at least one image of a surface generated by sectioning of the sample. With the aid of an evaluation device, the image of the surface is evaluated in terms of predefined characteristic values of a section quality. As a function of the characteristic values that are identified, a decision is then made as to whether the section of the sample is accepted or not. | 05-13-2010 |
| 20100112625 | METHOD AND APPARATUS FOR PROCESSING TISSUE SAMPLES USING A SENSOR - An apparatus and a method for processing tissue samples are described. The apparatus comprises: at least one retort for accommodating tissue samples; at least one container for storing alcohol or xylene; a valve adapted to connect the at least one retort with the at least one container depending on an operating position of the valve; and at least a first sensor that is arranged in flow direction between the container and the retort for measuring a value of a parameter that represents a purity level of the alcohol or xylene; wherein the first sensor and the valve are configured to replace the alcohol or xylene depending on the value of the parameter that represents the purity level. The method comprises for the alcohol or xylene conducting between the container and the retort; automatically measuring the purity level and replacing depending on the purity level. | 05-06-2010 |
| 20100112624 | METHOD FOR OPERATING A TISSUE PROCESSOR, AND TISSUE PROCESSOR - A method for operating a tissue processor and a respective tissue processor for performing this method are described for the processing tissue samples. The tissue processor comprises at least one retort for receiving the tissue samples and at least one container for receiving a process medium. The process medium is transferred at least one of from the container into the retort and from the retort into the container. A value is automatically measured in the course of transferring the process medium, the value representing a characteristic property of the process medium. The process medium is identified based on the value. | 05-06-2010 |
| 20100101385 | METHOD AND APPARATUS FOR OPERATING A MICROTOME - A method and apparatus for operating a microtome are described. According to the method, a specific type of a sample to be sectioned is detected, at least one stored sectioning parameter value is determined as a function of the specific type of the sample that was detected, said value being allocated to the specific type of the sample and defines a specific setting of the microtome, and the setting the microtome as defined by the determined sectioning parameter value is performed automatically. | 04-29-2010 |
| 20100099199 | METHOD AND APPARATUS FOR ASCERTAINING REAGENT QUALITY - A method for determining reagent quality in a device having multiple treatment stations for the treatment of at least one of cytological and histological prepared specimens and an apparatus for performing this method are described. The method comprises providing a carrier element that comprises at least one test material; transferring and treating the carrier element having test material according to a predefined sequence in a plurality of the treatment stations together with the specimens; and evaluating the test material by means of an evaluation device after treatment in the last treatment station in sequence. The described method and apparatus achieve that reagent quality can be determined automatically and the reagents can be replaced at an optimum point in time. | 04-22-2010 |
| 20100099133 | METHOD AND APPARATUS FOR THE TREATMENT OF SPECIMENS - A method and an apparatus for the treatment of cytological and histological specimens are described. A treatment program comprising multiple treatment parameters is predetermined. The specimens are introduced in accordance with the predetermined treatment program sequentially into a plurality of treatment stations by means of a transport device. At least one of the process data time and number of specimens subject to simultaneous treatment in one particular treatment station and number of the treatment stations during execution of the treatment program are determined. These process data are evaluated for optimizing the treatment program as to at least one of processing time, number of treatment stations and sequence of treatment stations. | 04-22-2010 |
| 20100086964 | APPARATUS AND METHOD FOR IDENTIFYING AT LEAST ONE SPECIMEN SLIDE - An apparatus and method for tagging a specimen slide are described. The apparatus comprises a receiving region for receiving at least one cassette magazine, a reading unit for reading the machine-readable coded information of a cassette identifier of a cassette, and a tagging unit for generating a machine-readable coded information for tagging the specimen slide with a specimen slide identifier that depends on the cassette identifier. Data are transferred from the microtome to the apparatus via the data transfer path as soon as the cassette is inserted into the microtome, and only then can the machine-readable coded information for tagging the specimen slide be applied onto the specimen slide by the tagging unit. | 04-08-2010 |
| 20100083777 | Apparatus and Method for Storing at Least One Specimen Slide and at Least One Cassette - An apparatus for storing at least one specimen slide and at least one cassette comprising a sample that is embedded in a sample block and that is to be processed, a microtome comprising this apparatus, and a method for handling multiple cassettes and multiple specimen slides are described. A cassette magazine receives at least one cassette having at least one sample block. A slide magazine receives at least one specimen slide. At least one connecting element for connecting the cassette magazine and the slide magazine mechanically with each other is provided. This allows handling at least one cassette and at least one specimen slide together in a simple and efficient manner. | 04-08-2010 |
| 20100068095 | DEVICE FOR MANIPULATING AT LEAST ONE SPECIMEN SLIDE - A device for manipulating at least one specimen slide. The device includes a first sensor unit operable to sense a first rotation of a first component of the device about at least one first axis of a three-dimensional coordinate system. A second sensor unit is operable to sense a second rotation of a second component of the device about the at least one first axis of the coordinate system, the coordinate system being independent of a position of the first component and of a position of the second component. A positioning unit is operable to position the second component relative to the first component. | 03-18-2010 |
| 20100068094 | APPARATUS FOR TREATING PREPARED SPECIMENS - An apparatus is described for treating prepared specimens. The apparatus comprises at least two container rows arranged in parallel to each other, each comprising a plurality of reagent containers and a transport mechanism for transporting at least one transport container that receives at least one carrier holding at least one prepared specimen. The transport mechanism is movable along an X and Z axis. A rotation unit is provided comprising holding arms and at least one holding element. The container rows are received rotatably at the ends of the holding arms of the at least one holding element that is connected to a rotation shaft such that it co-rotates with the rotation shaft that extends parallel to the X axis. The rotation unit is adapted to assume at least one working position allowing the transport mechanism to have access to the reagent container. | 03-18-2010 |
| 20100064867 | MICROTOME FOR PRODUCING SECTIONS OF SPECIMENS - The invention relates to a microtome and a method for producing sections of a specimen. The microtome has a knife for sectioning the specimen, and a cooling apparatus for cooling a gaseous coolant. The cooling apparatus generates a coolant flow of the gaseous coolant. The specimen is arranged in the coolant flow. | 03-18-2010 |
| 20100058913 | MICROTOME HAVING A CASSETTE CHANGING APPARATUS - A microtome is described, having a cassette changing apparatus that comprises a stationary guide bar. The latter guides a second slider that is a guide for the first slider. The first and the second slider are coupled to one another in such a way that a movement of the second slider along the stationary guide bar operates a movement of the first slider along with the second slider and additionally relative to the second slider. | 03-11-2010 |
| 20100058777 | APPARATUS FOR COOLING CASSETTE MAGAZINES CONTAINING TISSUE SAMPLES - An apparatus for cooling cassette magazines containing tissue samples is described. The apparatus comprises a housing, a cooling device, and a transport apparatus for transporting one or more cassette magazines within the housing. The cassette magazines are introduced into the apparatus via an input chute and can be removed via an output chute. | 03-11-2010 |
| 20100055788 | METHOD AND APPARATUS FOR INFILTRATING TISSUE SAMPLES WITH PARAFFIN - A method and an apparatus are described for infiltrating tissue samples with carrier material, preferably paraffin. A supply of carrier material is kept ready for use in a supply station. From there, the carrier material can be delivered into at least a first and a second container. In these first and second containers carrier materials of differing degrees of purity are kept ready for use, respectively, for performing various infiltration steps on tissue samples. By means of the described method and apparatus the tissue processor can be operated with as little interruptions as possible and an ease in operation is achieved. | 03-04-2010 |
| 20100055777 | TISSUE PROCESSOR - A tissue processor is described that comprises a retort for processing histological samples using various reagents, a plurality of exchangeable reagent supply containers that each comprise at least one container opening, a system of conduits, a control device for conveying reagents out of the reagent supply containers through at least one reagent conduit into the retort, and system bottles. The reagent supply containers and the system bottles are connected via the pertinent reagent conduits to at least one valve. The valve is electrically connected to the control device such that at least one of filling and emptying of the system bottles with reagents from the reagent supply containers is controlled. This design allows differently dimensioned reagent supply containers while at the same time minimizing the space requirement for the reagent containers. | 03-04-2010 |
| 20100055663 | METHOD FOR CONTROLLING A TISSUE PROCESSOR AND TISSUE PROCESSOR - A method for controlling a tissue processor and a tissue processor for processing tissue samples is described. A retort is provided comprising a cover that can be opened and closed by an operator. The retort cover is closed prior to tissue processing. The actuation state of a first and a second operating element can be determined. An operator is prompted to confirm unlocking of the closed retort cover by actuating a second operating element. The tissue processing is interrupted when an actuation of the second operating element is determined and the closed retort cover is unlocked and is continued after the retort cover is once again locked. After having completed tissue processing the retort cover is unlocked. By means of the described method and tissue processor improper intervention during ongoing tissue processing is prevented. | 03-04-2010 |
| 20090235799 | Knife Holder For Microtome Blades - A knife holder ( | 09-24-2009 |
| 20090148264 | OBJECT BLOCK MAGAZINE - A magazine having compartments for receiving cassettes has an outer housing having an open top and an open front side. An inner housing within the outer housing encloses an interior space and defines a plurality of compartments. The inner housing has opposing sidewalls, and spring elements form the compartments. A generally U-shaped feed element is mounted on the inner housing movably reciprocally in the longitudinal direction over a depth of the compartment so that the feed element moves a cassette from one compartment to an adjacent compartment. | 06-11-2009 |
| 20090146335 | Cassette Changing Device - A cassette changing device for a microtome has a housing having a loading opening, a transfer opening and an unloading opening. The openings are arranged with respect to each other linearly in the housing. A slide is disposed in the housing linearly movably between a first position and a second position and has a first receiving compartment and a second receiving compartment. The first and second compartments are aligned with respect to each other so that, in the first position of the slide, the first compartment and the second compartment are respectively aligned with a first two of the openings and, in the second position of the slide, the first compartment and the second compartment are respectively aligned with a second two of the openings. | 06-11-2009 |
| 20080286859 | Apparatus For Producing Thin Sections - An apparatus for producing flat thin sections of a specimen ( | 11-20-2008 |
| 20080199955 | Tissue Infiltration Apparatus - A tissue infiltration apparatus ( | 08-21-2008 |